ES2061576T3 - Modificacion polimorfica de buspirona farmaceuticamente util. - Google Patents

Modificacion polimorfica de buspirona farmaceuticamente util.

Info

Publication number
ES2061576T3
ES2061576T3 ES88113970T ES88113970T ES2061576T3 ES 2061576 T3 ES2061576 T3 ES 2061576T3 ES 88113970 T ES88113970 T ES 88113970T ES 88113970 T ES88113970 T ES 88113970T ES 2061576 T3 ES2061576 T3 ES 2061576T3
Authority
ES
Spain
Prior art keywords
buspirona
pharmaceutically useful
polymorphic modification
useful
polymorphic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88113970T
Other languages
English (en)
Inventor
Jack C Simms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22225222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2061576(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2061576T3 publication Critical patent/ES2061576T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Body Structure For Vehicles (AREA)

Abstract

LA INVENCION SE REFIERE A LA FORMA CRISTALINA POLIMORFICA DE BAJO PUNTO DE FUSION DE HIDROCLORURO DE BUSFIRONA QUE TIENE UN PUNTO DE FUSION DE 188 (GRADOS) C. ES UTIL PARA TRATAR LA ANSIEDAD EN UN PACIENTE QUE NECESITE TAL TRATAMIENTO.
ES88113970T 1987-08-28 1988-08-26 Modificacion polimorfica de buspirona farmaceuticamente util. Expired - Lifetime ES2061576T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/090,984 US5015646A (en) 1987-08-28 1987-08-28 Pharmaceutically useful polymorphic modification of buspirone

Publications (1)

Publication Number Publication Date
ES2061576T3 true ES2061576T3 (es) 1994-12-16

Family

ID=22225222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88113970T Expired - Lifetime ES2061576T3 (es) 1987-08-28 1988-08-26 Modificacion polimorfica de buspirona farmaceuticamente util.

Country Status (22)

Country Link
US (1) US5015646A (es)
EP (1) EP0304941B1 (es)
JP (1) JP2716740B2 (es)
KR (1) KR970011297B1 (es)
AT (1) ATE101147T1 (es)
AU (1) AU618549B2 (es)
CY (1) CY1785A (es)
DE (1) DE3887598T2 (es)
DK (1) DK170821B1 (es)
ES (1) ES2061576T3 (es)
FI (1) FI883961L (es)
HK (1) HK74494A (es)
HU (1) HU201322B (es)
IE (1) IE63071B1 (es)
IL (1) IL87468A (es)
MY (1) MY104061A (es)
NO (1) NO883805D0 (es)
NZ (1) NZ225896A (es)
OA (1) OA08908A (es)
PT (1) PT88356B (es)
YU (1) YU46962B (es)
ZA (1) ZA886082B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
HU217129B (hu) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
CN1275126A (zh) 1998-06-19 2000-11-29 帝人株式会社 2－(3－氰基－4－异丁氧基苯基)－4－甲基－5－噻唑甲酸的多晶型体及其制备方法
US6465255B1 (en) * 1999-01-29 2002-10-15 The Regents Of The University Of California Method for identifying and probing phase transitions in materials
KR100433165B1 (ko) * 2000-10-10 2004-05-27 엔앤비텍 주식회사 가공란의 제조 방법, 상기 방법에 의하여 제조된 가공란,및 가공란을 제조하기 위한 장치
CL2004001034A1 (es) 2003-05-14 2005-03-28 Teijin Pharma Ltd Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r
SI1750766T1 (sl) 2004-05-11 2013-11-29 Emotional Brain B.V. Farmacevtske formulacije in njihove uporabe pri zdravljenju spolne disfunkcije pri Ĺľenskah
US20080015240A1 (en) * 2004-11-12 2008-01-17 Mitsuru Teramoto Acid Salt of Benzimidazole Derivative and Crystal Thereof
EP1790343A1 (en) 2005-11-11 2007-05-30 Emotional Brain B.V. Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction
EP1925307A1 (en) 2006-11-03 2008-05-28 Emotional Brain B.V. Use of 3-alpha-androstanediol in the treatment of sexual dysfunction
CN118702676B (zh) * 2024-07-09 2026-01-27 济南大学 一种盐酸丁螺环酮晶型ii的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4351939A (en) * 1980-10-16 1982-09-28 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen

Also Published As

Publication number Publication date
IL87468A0 (en) 1989-01-31
ZA886082B (en) 1989-04-26
DE3887598D1 (de) 1994-03-17
DK478788D0 (da) 1988-08-26
HK74494A (en) 1994-08-05
IL87468A (en) 1992-12-01
PT88356A (pt) 1989-06-30
US5015646A (en) 1991-05-14
CY1785A (en) 1995-10-20
EP0304941B1 (en) 1994-02-02
JP2716740B2 (ja) 1998-02-18
AU618549B2 (en) 1992-01-02
YU161688A (en) 1990-10-31
IE63071B1 (en) 1995-03-22
PT88356B (pt) 1995-03-31
DK170821B1 (da) 1996-01-29
HU201322B (en) 1990-10-28
FI883961A7 (fi) 1989-03-01
IE882528L (en) 1989-02-28
MY104061A (en) 1993-11-30
EP0304941A1 (en) 1989-03-01
KR890003740A (ko) 1989-04-17
FI883961L (fi) 1989-03-01
AU2107688A (en) 1989-03-02
DK478788A (da) 1989-03-01
DE3887598T2 (de) 1994-05-19
JPS6471816A (en) 1989-03-16
HUT47564A (en) 1989-03-28
OA08908A (en) 1989-10-31
YU46962B (sh) 1994-09-09
KR970011297B1 (ko) 1997-07-09
ATE101147T1 (de) 1994-02-15
FI883961A0 (fi) 1988-08-26
NO883805D0 (no) 1988-08-25
NZ225896A (en) 1991-04-26

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