ES2061610T3 - Nuevos derivados hidrogenados de antibiotico a/16686. - Google Patents

Nuevos derivados hidrogenados de antibiotico a/16686.

Info

Publication number
ES2061610T3
ES2061610T3 ES88119001T ES88119001T ES2061610T3 ES 2061610 T3 ES2061610 T3 ES 2061610T3 ES 88119001 T ES88119001 T ES 88119001T ES 88119001 T ES88119001 T ES 88119001T ES 2061610 T3 ES2061610 T3 ES 2061610T3
Authority
ES
Spain
Prior art keywords
antibiotic
hydrogenated derivatives
new hydrogenated
factors
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88119001T
Other languages
English (en)
Inventor
Romeo Ciabatti
Bruno Cavalleri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of ES2061610T3 publication Critical patent/ES2061610T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)

Abstract

LA INVENCION ES CONCERNIENTE A TETRAHIDRODERIVADOS DE FACTORES A1, A2, A3, A 1, A 2, A 3 DE ANTIBIOTICO A 16686 Y MEZCLAS DE ELLOS. LOS TETRAHIDRODERIVADOS SON PRODUCIDOS POR HIDROGENACION DE LOS FACTORES ANTES MENCIONADOS PREFERIBLEMENTE POR HIDROGENACION CATALITICA. LOS COMPUESTOS TIENEN CATIVIDAD ANTIBACTERIANA, EN PARTICULAR, CONTRA UN ANCHO ESPECTRO DIFUSO DE BACTERIAS GRAM POSITIVAS Y TIENE USOS PARTICULARES PARA TRATAMIENTO TOPICO DE HERIDAS INFECTADAS Y ACNE
ES88119001T 1987-12-23 1988-11-15 Nuevos derivados hidrogenados de antibiotico a/16686. Expired - Lifetime ES2061610T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878729989A GB8729989D0 (en) 1987-12-23 1987-12-23 Novel hydrogenated derivatives of antibiotic a/16686

Publications (1)

Publication Number Publication Date
ES2061610T3 true ES2061610T3 (es) 1994-12-16

Family

ID=10628943

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88119001T Expired - Lifetime ES2061610T3 (es) 1987-12-23 1988-11-15 Nuevos derivados hidrogenados de antibiotico a/16686.

Country Status (11)

Country Link
US (1) US5108988A (es)
EP (1) EP0321696B1 (es)
JP (1) JP2507573B2 (es)
KR (1) KR890009964A (es)
AT (1) ATE99329T1 (es)
CA (1) CA1338848C (es)
DE (1) DE3886718T2 (es)
DK (1) DK690288A (es)
ES (1) ES2061610T3 (es)
GB (1) GB8729989D0 (es)
IE (1) IE883840L (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621911D0 (en) * 1986-09-11 1986-10-15 Lepetit Spa Increasing ratio of components of anti-biotic complex
GB8729989D0 (en) * 1987-12-23 1988-02-03 Lepetit Spa Novel hydrogenated derivatives of antibiotic a/16686
GB8808658D0 (en) * 1988-04-13 1988-05-18 Lepetit Spa Aglycons of a/16686 antibiotics
EP0912604B1 (en) 1996-04-23 2001-11-14 Biosearch Italia S.p.A. Improved chemical process for preparing amide derivatives of antibiotic A 40926
EP0976394A1 (en) * 1998-07-30 2000-02-02 Biosearch Italia S.p.A. New injectable formulations
AU2003212278A1 (en) * 2002-03-08 2003-09-22 Vicuron Pharmaceuticals Inc. A process for the production of ramoplanin-like amide derivatives
US7317001B2 (en) 2002-06-06 2008-01-08 Oscient Pharmaceuticals Corporation Use of ramoplanin to treat diseases associated with the use of antibiotics
WO2004017925A2 (en) * 2002-08-23 2004-03-04 Genome Therapeutics Corporation Methods and reagents for preventing bacteremias
US20040127403A1 (en) * 2002-09-06 2004-07-01 Francesco Parenti Methods for treating and preventing Gram-positive bacteremias
US20050043223A1 (en) * 2003-04-25 2005-02-24 Leach Timothy S. Methods for reducing or preventing transmission of nosocomial pathogens in a health care facility
US8252339B2 (en) * 2006-04-11 2012-08-28 Massachusetts Institute Of Technology Medical treatment applications of swellable and deformable microspheres
NZ616764A (en) * 2009-12-14 2014-11-28 Univ Basel Mannose derivatives as antagonists of bacterial adhesion

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA801629B (en) * 1979-04-07 1981-03-25 Lepetit Spa Antibiotic a/16686 and process for the preparation thereof
EP0046201B1 (en) * 1980-08-16 1984-04-11 Gruppo Lepetit S.P.A. Antibiotic a/16686 factor a2, the process for the preparation thereof, and the co-produced antibiotic a/16686 factors a1 and a3
GB8729989D0 (en) * 1987-12-23 1988-02-03 Lepetit Spa Novel hydrogenated derivatives of antibiotic a/16686

Also Published As

Publication number Publication date
US5108988A (en) 1992-04-28
DK690288D0 (da) 1988-12-12
GB8729989D0 (en) 1988-02-03
ATE99329T1 (de) 1994-01-15
DE3886718D1 (de) 1994-02-10
IE883840L (en) 1989-06-23
KR890009964A (ko) 1989-08-05
EP0321696B1 (en) 1993-12-29
CA1338848C (en) 1997-01-14
DK690288A (da) 1989-06-24
JPH01211600A (ja) 1989-08-24
DE3886718T2 (de) 1994-04-28
EP0321696A3 (en) 1990-07-11
JP2507573B2 (ja) 1996-06-12
EP0321696A2 (en) 1989-06-28

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