ES2061678T3 - Nuevo procedimiento para la preparacion de un octapeptido. - Google Patents

Nuevo procedimiento para la preparacion de un octapeptido.

Info

Publication number
ES2061678T3
ES2061678T3 ES88309306T ES88309306T ES2061678T3 ES 2061678 T3 ES2061678 T3 ES 2061678T3 ES 88309306 T ES88309306 T ES 88309306T ES 88309306 T ES88309306 T ES 88309306T ES 2061678 T3 ES2061678 T3 ES 2061678T3
Authority
ES
Spain
Prior art keywords
formula
group
octapeptide
compound
carboxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88309306T
Other languages
English (en)
Inventor
Mauro Galantino
Romualdo Forino
Castiglione Roberto De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of ES2061678T3 publication Critical patent/ES2061678T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/065—Thymic humoral factor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PREPARAN UN OCTAPEPTIDO PROVISTO DE ACTIVIDAD HUMORAL TIMICA, DE FORMULA(A) H - LEN - GLU - ASP - GLY - LYS - PHE - LEN - OH, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, MEDIANTE CONDENSACION DE UN COMPUESTO DE FORMULA(B) (I) (EN LA QUE X ES UN GRUPO PROTECTOR DE AMINO, Y E Y''SON AMBOS OPCIONALES Y REPRESENTAN INDEPENDIENTEMENTE UN GRUPO PROTECTOR DE CARBOXI Y K ES UN GRUPO HIDROXI O HIDRAZIDO), CON UN COMPUESTO DE FORMULA(C) (II), (DONDE W ES UN GRUPO PROTECTOR DE AMINO, Y Q ES UN GRUPO PROTECTOR DE CARBOXI O UN GRUPO HIDROXI), DESPROTEGIENDO EL COMPUESTO RESULTANTE DE FORMULA(D) (III), (DONDE X, Y, Y'', W Y Q SON LOS ANTES DEFINIDOS), Y SI DESEA, CONVIRTIENDO EL PEPTIDO RESULTANTE DE FORMULA(A) EN UNA SAL SUYA FARMACEUTICAMENTE ACEPTABLE.
ES88309306T 1987-10-07 1988-10-06 Nuevo procedimiento para la preparacion de un octapeptido. Expired - Lifetime ES2061678T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878723484A GB8723484D0 (en) 1987-10-07 1987-10-07 Preparing octapeptide

Publications (1)

Publication Number Publication Date
ES2061678T3 true ES2061678T3 (es) 1994-12-16

Family

ID=10624894

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88309306T Expired - Lifetime ES2061678T3 (es) 1987-10-07 1988-10-06 Nuevo procedimiento para la preparacion de un octapeptido.

Country Status (7)

Country Link
EP (1) EP0311391B1 (es)
JP (1) JPH01128998A (es)
AT (1) ATE99321T1 (es)
AU (1) AU606460B2 (es)
DE (1) DE3886655T2 (es)
ES (1) ES2061678T3 (es)
GB (1) GB8723484D0 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8723485D0 (en) * 1987-10-07 1987-11-11 Erba Farmitalia Solution synthesis of octapeptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8723485D0 (en) * 1987-10-07 1987-11-11 Erba Farmitalia Solution synthesis of octapeptide

Also Published As

Publication number Publication date
JPH01128998A (ja) 1989-05-22
EP0311391A3 (en) 1990-05-16
AU2339188A (en) 1989-04-13
AU606460B2 (en) 1991-02-07
ATE99321T1 (de) 1994-01-15
EP0311391A2 (en) 1989-04-12
GB8723484D0 (en) 1987-11-11
DE3886655D1 (de) 1994-02-10
EP0311391B1 (en) 1993-12-29
DE3886655T2 (de) 1994-04-14

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