ES2061880T3 - Composicion y metodo de granulacion. - Google Patents
Composicion y metodo de granulacion.Info
- Publication number
- ES2061880T3 ES2061880T3 ES89119580T ES89119580T ES2061880T3 ES 2061880 T3 ES2061880 T3 ES 2061880T3 ES 89119580 T ES89119580 T ES 89119580T ES 89119580 T ES89119580 T ES 89119580T ES 2061880 T3 ES2061880 T3 ES 2061880T3
- Authority
- ES
- Spain
- Prior art keywords
- formulation
- ingredients
- tablets
- granulation
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000005469 granulation Methods 0.000 title 1
- 230000003179 granulation Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000004615 ingredient Substances 0.000 abstract 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- WRUGWIBCXHJTDG-UHFFFAOYSA-L magnesium sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Mg+2].[O-]S([O-])(=O)=O WRUGWIBCXHJTDG-UHFFFAOYSA-L 0.000 abstract 1
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 abstract 1
- 235000019982 sodium hexametaphosphate Nutrition 0.000 abstract 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
EL INVENTO SE REFIERE A COMPOSICIONES GRANULANTES COMPUESTAS DE UNA SOLUCION ACUOSA DE HEPTAHIDRATO DE SULFATO DE MAGNESIO Y HEXAMETAFOSFATO DE SODIO. ESTE COMPUESTO PUEDE USARSE PARA PREPARAR GRANULOS O INGREDIENTES PARA SU INCLUSION EN CUAQUIER FORMULACION PARA LA CUAL LA DESINTEGRACION O DISPERSION SEAN FACTORES IMPORTANTES. ES UTIL PARA TABLETAS QUE CONTENGAN INGREDINTES QUE SEAN DIFICILES DE COMPRIMIR Y ES PARTICULARMENTE UTIL PARA LA FORMULACION DE TABLETAS DEGLUTIBLES DE UN INGREDIENTE SIMPLE NO SOLUBLE COMO EL CARBONATO DE CALCIO. LOS TIEMPOS DE DISGREGACION SE REDUCEN DE FORMA APECIABLE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/266,649 US4965072A (en) | 1988-11-03 | 1988-11-03 | Granulating composition and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2061880T3 true ES2061880T3 (es) | 1994-12-16 |
Family
ID=23015430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89119580T Expired - Lifetime ES2061880T3 (es) | 1988-11-03 | 1989-10-21 | Composicion y metodo de granulacion. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4965072A (es) |
| EP (1) | EP0367056B1 (es) |
| JP (1) | JP2921886B2 (es) |
| DE (1) | DE68912515T2 (es) |
| ES (1) | ES2061880T3 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU639137B2 (en) * | 1990-09-21 | 1993-07-15 | Merrell Dow Pharmaceuticals Inc. | Superior tasting pharmaceutical composition having porous particles and the process of preparing such pharmaceutical composition |
| UA37214C2 (uk) * | 1991-01-30 | 2001-05-15 | Дзе Веллкам Фаундейшн Лімітед | Таблетки, що диспергуються у воді, та спосіб їх виготовлення |
| US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| GB9215908D0 (en) * | 1992-07-27 | 1992-09-09 | Wellcome Found | Water dispersible tablets |
| US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5498425A (en) * | 1995-03-17 | 1996-03-12 | Block Drug Company, Inc. | Phosphosoda buffered saline laxative |
| US6043100A (en) * | 1996-04-19 | 2000-03-28 | Weaver; Kevin | Chip on tape die reframe process |
| US5807580A (en) * | 1996-10-30 | 1998-09-15 | Mcneil-Ppc, Inc. | Film coated tablet compositions having enhanced disintegration characteristics |
| US5843477A (en) * | 1997-09-30 | 1998-12-01 | Bayer Corporation | Lubricants for use in tabletting |
| US5955107A (en) * | 1997-12-12 | 1999-09-21 | Fmc Corporation | Pharmaceutical suspension tablet compositions |
| US8231899B2 (en) | 1998-09-10 | 2012-07-31 | Nycomed Danmark Aps | Quick release pharmaceutical compositions of drug substances |
| EA004032B1 (ru) * | 1998-09-10 | 2003-12-25 | Нюкомед Данмарк А/С | Фармацевтические композиции лекарственных веществ с быстрым высвобождением |
| US6887492B2 (en) | 2000-12-14 | 2005-05-03 | Leiner Health Services Corp. | Magnesium plus interactive agent delivery |
| EP2493454A2 (en) | 2009-10-28 | 2012-09-05 | McNeil-PPC, Inc. | Fast dissolving/disintegrating coating compositions |
| CN107668726A (zh) * | 2017-10-19 | 2018-02-09 | 安徽珠峰生物科技有限公司 | 一种含氨基酸鳌合钙的b族维生素片的薄膜包衣工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3297529A (en) * | 1964-11-25 | 1967-01-10 | Sutton Lab Inc | Magnesium sulfate stabilized choline salicylate |
| DE2158943A1 (de) * | 1970-12-03 | 1972-06-29 | Scherico Ltd., Luzern (Schweiz) | Moussierende Zubereitungen |
| US4201756A (en) * | 1972-07-31 | 1980-05-06 | Olin Corporation | Granular calcium hypochlorite coated with an inorganic salt |
| US4196851A (en) * | 1978-09-20 | 1980-04-08 | Treasure Masters Corp. | Scented sachet tablet |
| US4439453A (en) * | 1980-12-22 | 1984-03-27 | Monsanto Company | Directly compressible acetaminophen granulation |
| US4582709A (en) * | 1985-02-08 | 1986-04-15 | Warner-Lambert Company | Chewable mineral supplement |
-
1988
- 1988-11-03 US US07/266,649 patent/US4965072A/en not_active Expired - Lifetime
-
1989
- 1989-10-21 ES ES89119580T patent/ES2061880T3/es not_active Expired - Lifetime
- 1989-10-21 DE DE68912515T patent/DE68912515T2/de not_active Expired - Fee Related
- 1989-10-21 EP EP89119580A patent/EP0367056B1/en not_active Expired - Lifetime
- 1989-11-02 JP JP1285148A patent/JP2921886B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE68912515T2 (de) | 1994-09-29 |
| JPH02180814A (ja) | 1990-07-13 |
| JP2921886B2 (ja) | 1999-07-19 |
| EP0367056A2 (en) | 1990-05-09 |
| EP0367056A3 (en) | 1991-03-13 |
| US4965072A (en) | 1990-10-23 |
| EP0367056B1 (en) | 1994-01-19 |
| DE68912515D1 (de) | 1994-03-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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