ES2061944T3 - Conjugado de peptido inmunologicamente activo ppd (nanp)n util como vacuna antimalaria. - Google Patents

Conjugado de peptido inmunologicamente activo ppd (nanp)n util como vacuna antimalaria.

Info

Publication number
ES2061944T3
ES2061944T3 ES89201985T ES89201985T ES2061944T3 ES 2061944 T3 ES2061944 T3 ES 2061944T3 ES 89201985 T ES89201985 T ES 89201985T ES 89201985 T ES89201985 T ES 89201985T ES 2061944 T3 ES2061944 T3 ES 2061944T3
Authority
ES
Spain
Prior art keywords
ppd
conjugate
peptide conjugate
immunologically active
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89201985T
Other languages
English (en)
Inventor
Antonio Silvio Verdini
Antonello Pessi
Giudice Giuseppe Del
Paul Henry Lambert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eni Tecnologie SpA
Original Assignee
Eniricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche SpA filed Critical Eniricerche SpA
Application granted granted Critical
Publication of ES2061944T3 publication Critical patent/ES2061944T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE DESCRIBE UN CONJUGADO DE PEPTIDO INMUNOLOGICAMENTE ACTIVO, FORMADO A PARTIR DE LA UNION DE UN PEPTIDO SINTETICO, QUE TIENE UNA SECUENCIA DE AMINOACIDOS IGUAL O ANALOGA A LA DE POR LO MENOS UN EPITOPO INMUNODOMINANTE DE LA PROTEINA CIRCUNSPOROZOITICA DE PLASMODIUM, CON EL DERIVADO PROTEINICO PURIFICADO DE TUBERCULINA (PPD). DICHO CONJUGADO ES CAPAZ DE ESTIMULAR CON MUCHA EFICACIA LA PRODUCCION DE ANTICUERPOS ANTIESPOROZOITOS DE PLASMODIUM AUN EN AUSENCIA DE COADYUVANTES. LA RESPUESTA DEL ANTICUERPO A ESTE INMUNOGENO NO ESTA RESTRINGIDA GENITALMENTE Y ES ESPECIALMENTE EFICAZ CUANDO EL ANIMAL ESTA VACUNADO CON BACILO CALMETTE-GUERIN ANTES DE ADMINISTRAR EL CONJUGADO. DICHO CONJUGADO DE PEPTIDO ES ESPECIALMENTE UTIL EN LA PREPARACION DE VACUNAS ANTIMALARIA.
ES89201985T 1988-08-05 1989-07-28 Conjugado de peptido inmunologicamente activo ppd (nanp)n util como vacuna antimalaria. Expired - Lifetime ES2061944T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821666A IT1226728B (it) 1988-08-05 1988-08-05 Coniugato peptidico immunologicamente attivo utile come vaccino antimalaria e metodo di immunizzazione impiegante lo stesso

Publications (1)

Publication Number Publication Date
ES2061944T3 true ES2061944T3 (es) 1994-12-16

Family

ID=11185073

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89201985T Expired - Lifetime ES2061944T3 (es) 1988-08-05 1989-07-28 Conjugado de peptido inmunologicamente activo ppd (nanp)n util como vacuna antimalaria.

Country Status (5)

Country Link
EP (1) EP0353823B1 (es)
AT (1) ATE99955T1 (es)
DE (1) DE68912229T2 (es)
ES (1) ES2061944T3 (es)
IT (1) IT1226728B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2125467C (en) * 1993-07-06 2001-02-06 Heinz Dobeli Process for producing hydrophobic polypeptides, proteins or peptides
WO1998048824A1 (en) * 1997-05-01 1998-11-05 Emory University Bioactive peptides derived from cocaine and amphetamine regulated transcript protein

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849551A (en) * 1972-09-28 1974-11-19 Antonio L D Bcg as adjuvant in malaria vaccination
WO1985000975A1 (en) * 1983-08-19 1985-03-14 University Of Illinois Method and materials for development of immunological responses protective against malarial infection
ZA855232B (en) * 1984-07-23 1986-02-26 Univ New York Protective peptide antigen corresponding to plasmodium falciparum circumsporozoite protein
ES8800273A1 (es) * 1985-03-28 1987-11-01 Univ New York Perfeccionamientos en la fabricacion de conjugados de proteinas portadores de antigenos inmunogenicos para vacunas contra la malaria
IT1187710B (it) * 1985-07-25 1987-12-23 Eniricerche Spa Composizione peptidica utile per la preparazione di vaccini per la malaria e di kit diagnostici per la determinazione di affezioni malariche

Also Published As

Publication number Publication date
EP0353823A1 (en) 1990-02-07
EP0353823B1 (en) 1994-01-12
DE68912229D1 (de) 1994-02-24
IT1226728B (it) 1991-02-05
IT8821666A0 (it) 1988-08-05
DE68912229T2 (de) 1994-05-19
ATE99955T1 (de) 1994-01-15

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