ES2061996T3 - Regiones no esenciales de avipoxvirus. - Google Patents

Regiones no esenciales de avipoxvirus.

Info

Publication number
ES2061996T3
ES2061996T3 ES89306326T ES89306326T ES2061996T3 ES 2061996 T3 ES2061996 T3 ES 2061996T3 ES 89306326 T ES89306326 T ES 89306326T ES 89306326 T ES89306326 T ES 89306326T ES 2061996 T3 ES2061996 T3 ES 2061996T3
Authority
ES
Spain
Prior art keywords
fpv
viruses
dna
vaccine
avipoxviruses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89306326T
Other languages
English (en)
Inventor
Matthew Kckinley Binns
Michael Edward Griff Boursnell
Joan Iyabo Amiemenogh Campbell
Fiona Margaret Tomley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888815098A external-priority patent/GB8815098D0/en
Priority claimed from GB898904411A external-priority patent/GB8904411D0/en
Priority claimed from GB898907374A external-priority patent/GB8907374D0/en
Priority claimed from GB898910520A external-priority patent/GB8910520D0/en
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Application granted granted Critical
Publication of ES2061996T3 publication Critical patent/ES2061996T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A DNA DE VIRUS DE SIFILIS AVIAR (FPV), PROPORCIONANDO UNA REGION NO ESENCIAL PARA LA INSERCION DE GENES EXTRAÑOS EN EL, Y DE AHI LA CONSTRUCCION DE UN VECTOR PARA RECOMBINACION HOMOLOGA CON UN FPV TIPO SILVESTRE, CON LO QUE EL FPV RECOMBINANTE QUE RESULTA SE PUEDE UTILIZAR PARA VACUNAR ANIMALES, ESPECIALMENTE GALLINAS. EN ESTA INVENCION, LA REGION NO ESENCIAL CONSTA ESENCIALMENTE DE UN CORTE DE DNA DE LA SECUENCIA UNICA LARGA DE LA REPITICION INVERTIDA TERMINAL (TIR) DE FPV O DE LA REGION EN LA QUE EL FPV CORRESPONDE APROXIMADAMENTE A LOS GENES D8 Y D9 DEL FRAGMENTO D DE HIND III EN VIRUS DE VACUNAS.
ES89306326T 1988-06-24 1989-06-22 Regiones no esenciales de avipoxvirus. Expired - Lifetime ES2061996T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB888815098A GB8815098D0 (en) 1988-06-24 1988-06-24 Fowlpox virus non-essential regions
GB898904411A GB8904411D0 (en) 1989-02-27 1989-02-27 Fowlpox virus non-essential regions(2)
GB898907374A GB8907374D0 (en) 1989-03-31 1989-03-31 Fowlpox virus non-essential regions(3)
GB898910520A GB8910520D0 (en) 1989-05-08 1989-05-08 Fowlpox virus non-essential regions(4)

Publications (1)

Publication Number Publication Date
ES2061996T3 true ES2061996T3 (es) 1994-12-16

Family

ID=27450125

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89306326T Expired - Lifetime ES2061996T3 (es) 1988-06-24 1989-06-22 Regiones no esenciales de avipoxvirus.

Country Status (10)

Country Link
US (1) US5310671A (es)
EP (1) EP0353851B1 (es)
JP (1) JP2538367B2 (es)
AU (1) AU623913B2 (es)
DE (1) DE68912441T2 (es)
DK (1) DK304390A (es)
ES (1) ES2061996T3 (es)
GB (1) GB2220941B (es)
PT (1) PT90967B (es)
WO (1) WO1989012684A1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833975A (en) * 1989-03-08 1998-11-10 Virogenetics Corporation Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence
US5505941A (en) * 1981-12-24 1996-04-09 Health Research, Inc. Recombinant avipox virus and method to induce an immune response
US5174993A (en) * 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
US7767449B1 (en) 1981-12-24 2010-08-03 Health Research Incorporated Methods using modified vaccinia virus
US7045313B1 (en) 1982-11-30 2006-05-16 The United States Of America As Represented By The Department Of Health And Human Services Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA
DE10399032I1 (de) * 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
FR2632863B2 (fr) * 1987-10-29 1990-08-31 Transgene Sa Virus du fowlpox recombinant et vaccins derives de ces virus
DE3813093A1 (de) * 1988-04-19 1989-11-09 Immuno Ag Rekombinantes plasmid, verfahren zum herstellen eines rekombinanten avipoxvirus, rekombinantes avipoxvirus und dessen verwendung
US5093258A (en) * 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
EP0419666A4 (en) * 1988-12-29 1991-05-15 Nippon Zeon Co., Ltd. Promoter, plasmid containing the same, and recombinant avipoxvirus
AU625584B2 (en) * 1989-03-08 1992-07-16 Health Research Inc. Recombinant poxvirus host selection system
US5759552A (en) * 1991-03-07 1998-06-02 Virogenetics Corporation Marek's disease virus recombinant poxvirus vaccine
BE1004877A3 (fr) * 1991-05-27 1993-02-16 Solvay Virus de l'avipox recombinant, culture de cellules infectees par ce virus et vaccins pour la volaille derives de ce virus.
US5369025A (en) * 1991-06-28 1994-11-29 The United States Of America As Represented By The Secretary Of Agriculture Recombinant fowlpox vaccine for protection against Marek's disease
AU657144B2 (en) * 1991-07-09 1995-03-02 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Recombinant Marek's disease virus, process for preparing the same and vaccine containing the same
EP0597016A4 (en) * 1991-07-26 1996-04-24 Virogenetics Corp Infectious bursal disease virus recombinant poxvirus vaccine.
EP1380651A2 (en) * 1991-08-26 2004-01-14 Baxter Healthcare S.A. Recombinant fowlpox virus with intact FPV-tk-gene
FR2682966B1 (fr) * 1991-10-29 1994-12-02 Rhone Merieux Preparation d'antigenes et de vaccins du virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5443831A (en) * 1991-10-29 1995-08-22 University Of Delaware Gene encoding glycoprotein B of Infectious Laryngotracheitis Virus
US5869312A (en) * 1992-01-13 1999-02-09 Syntro Corporation Recombinant swinepox virus
US6033904A (en) * 1992-01-13 2000-03-07 Syntro Corporation Recombinant swinepox virus
US6127163A (en) * 1992-01-13 2000-10-03 Syntro Corporation Recombinant swinepox virus
DE69333728T2 (de) * 1992-01-13 2006-08-31 Virogenetics Corp. Redombinanter Poxvirus als Impfstoff gegen den Virus der Marek-Krankheit.
US6251403B1 (en) 1992-01-13 2001-06-26 Syntro Corporation Recombinant swinepox virus
US6497882B1 (en) 1992-01-13 2002-12-24 Syntro Corporation Recombinant swinepox virus
US6328975B1 (en) 1992-01-13 2001-12-11 Syntro Corporation Recombinant swinepox virus
EP0696204A4 (en) * 1993-02-26 1999-03-31 Syntro Corp Recombined chickenpox virus and its use
US5925358A (en) * 1993-02-26 1999-07-20 Syntro Corporation Recombinant fowlpox viruses and uses thereof
US6136318A (en) * 1993-02-26 2000-10-24 Cochran; Mark D. Recombinant fowlpox viruses and uses thereof
US6875856B2 (en) 1993-09-24 2005-04-05 Syntro Corporation Recombinant infectious laryngotracheitis virus and uses thereof
JPH09505726A (ja) * 1993-09-24 1997-06-10 シントロ・コーポレーション 組換え感染性喉頭気管炎ウイルス及びそれらの使用
US5882856A (en) * 1995-06-07 1999-03-16 Genzyme Corporation Universal primer sequence for multiplex DNA amplification
FR2757061B1 (fr) * 1996-12-16 1999-03-26 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire
US6335185B1 (en) 1998-02-03 2002-01-01 University Technologies International Inc. Bacteriophage vectors generated by bacteriophage/plasmid recombination
CA2375189C (en) * 1999-05-28 2010-02-09 The Government Of The United States Of America A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
US7897146B2 (en) 2003-11-17 2011-03-01 Crusade Laboratories Limited Treatment using herpes simplex virus
GB0326798D0 (en) 2003-11-17 2003-12-24 Crusade Lab Ltd Methods for generating mutant virus
JP2007511216A (ja) 2003-11-17 2007-05-10 クルセイド ラボラトリーズ リミテッド 変異ウイルス

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5174993A (en) * 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
ATE21840T1 (de) * 1982-01-18 1986-09-15 Stephen David Mills Halter fuer stopfen von giessgefaessen.
WO1986000528A1 (en) * 1984-07-05 1986-01-30 Genex Corporation Cloned gene and method for making and using the same
WO1988002022A1 (en) * 1986-09-22 1988-03-24 Commonwealth Scientific And Industrial Research Or Recombinant poxviruses
EP0284416B1 (en) * 1987-03-27 1995-02-22 Nippon Zeon Co., Ltd. Recombinant avipoxyvirus
DE10399032I1 (de) * 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
CA1340203C (en) * 1987-09-16 1998-12-15 Noboru Yanagida Recombinant apivoxvirus
FR2632863B2 (fr) * 1987-10-29 1990-08-31 Transgene Sa Virus du fowlpox recombinant et vaccins derives de ces virus
US5093258A (en) * 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
EP0419666A4 (en) * 1988-12-29 1991-05-15 Nippon Zeon Co., Ltd. Promoter, plasmid containing the same, and recombinant avipoxvirus

Also Published As

Publication number Publication date
GB2220941B (en) 1991-09-11
DE68912441T2 (de) 1994-05-11
DK304390D0 (da) 1990-12-21
EP0353851A1 (en) 1990-02-07
AU3853789A (en) 1990-01-12
GB2220941A (en) 1990-01-24
WO1989012684A1 (en) 1989-12-28
GB8914306D0 (en) 1989-08-09
US5310671A (en) 1994-05-10
DE68912441D1 (de) 1994-03-03
JPH03502524A (ja) 1991-06-13
AU623913B2 (en) 1992-05-28
PT90967B (pt) 1993-07-30
EP0353851B1 (en) 1994-01-19
DK304390A (da) 1990-12-21
JP2538367B2 (ja) 1996-09-25
PT90967A (pt) 1989-12-29

Similar Documents

Publication Publication Date Title
ES2061996T3 (es) Regiones no esenciales de avipoxvirus.
ES2124532T3 (es) Sistema vector-huesped utilizable en terapia genica.
MX9202512A (es) Virus de avipox recombinante, cultivo de celulas infectadas por este virusy vacunas para las aves de corral derivadas de este virus.
ES2664505T3 (es) Secuencias de serotipo 9 de virus adeno-asociado (AAV), vectores que las contienen, y usos de las mismas
ES8500322A1 (es) Un metodo de modificar un virus para conferirle una nueva funcion biologica.
ES2140418T3 (es) Flavivirus quimericos y/o flavivirus de crecimiento restringido.
DE69737058D1 (de) Rekombinante hunde-herpesviren
CY1120856T1 (el) Μεθοδοι παραδοσης γονιδιων
ES2143507T3 (es) Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia.
ES2165405T3 (es) Cepas de vacuna europeas del virus del sindrome reproductor y respiratorio porcino (prrsv).
ES2061708T3 (es) Virus recombinante de la viruela de la gallina, vectores de expresion de proteinas heterologas y vacunas para aves de corral derivadas de este virus.
ES2195998T3 (es) Sistemas de expresion de dna basados en alfavirus.
ES2053413T3 (es) Peptidos que inducen anticuerpos que neutralizan aislados de vih-1 geneticamente divergentes.
ES2075901T3 (es) Sistemas de expresion de virus recombinantes de arn con cadena negativa y vacunas.
CO4650230A1 (es) Vacuna viva recombinante aviaria, utilizando como vector el virus de la laringotraqueitis infecciosa aviaria
ATE420190T1 (de) Rekombinanter lebendimpfstoff, der katzenherpesvirus typ i enthält, insbesondere für die behandlung von infektiöser bauchfellentzündung bei katzen
CL2024002582A1 (es) Polipéptidos f y h del virus del moquillo canino (cdv), composición; y uso.
ES2056565T3 (es) Virus recombinante de la enfermedad de marek.
ES2109189A1 (es) Vectores basados en genomas virales defectivos recombinantes y su empleo en la formulacion de vacunas.
AR094725A1 (es) Parvovirus 5a porcino, métodos de uso y vacuna
CY1106570T1 (el) Σταθερες, εξασθενημενες μεταλλαγμενες μορφες ιου λυσσας και ζωντανια εμβολια αυτων
AR019250A1 (es) Formas atenuadas del virus de la diarrea viral bovina, molecula de acido nucleico, vector, uso, metodo para modificar el genoma viral de tipo salvaje, genoma modificado, vacuna, metodo para atenuar un virus bvd de tipo salvaje
ES2076930T3 (es) Moleculas de adn utiles en la proteccion de plantas.
ES2118242T3 (es) Vacunas anti virus de la inmunodeficiencia felina (fiv).
DE69110897D1 (de) Hemmung der viralen replikation.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 353851

Country of ref document: ES