ES2062940A1 - Gastrokinetic agent, process for its preparation and pharmaceutical compositions containing said agent - Google Patents
Gastrokinetic agent, process for its preparation and pharmaceutical compositions containing said agentInfo
- Publication number
- ES2062940A1 ES2062940A1 ES09300493A ES9300493A ES2062940A1 ES 2062940 A1 ES2062940 A1 ES 2062940A1 ES 09300493 A ES09300493 A ES 09300493A ES 9300493 A ES9300493 A ES 9300493A ES 2062940 A1 ES2062940 A1 ES 2062940A1
- Authority
- ES
- Spain
- Prior art keywords
- agent
- preparation
- pharmaceutical compositions
- compositions containing
- gastrokinetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002640 gastrokinetic effect Effects 0.000 title 1
- BYHKGNWKJMGHGE-UHFFFAOYSA-N 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1,3-benzothiazole Chemical compound C1=C2OCOC2=CC(CN2CCN(CC2)C=2SC3=CC=CC=C3N=2)=C1 BYHKGNWKJMGHGE-UHFFFAOYSA-N 0.000 abstract 1
- LLQMZXMBCQNMJV-UHFFFAOYSA-N 2-piperazin-1-yl-1,3-benzothiazole Chemical class C1CNCCN1C1=NC2=CC=CC=C2S1 LLQMZXMBCQNMJV-UHFFFAOYSA-N 0.000 abstract 1
- 230000005176 gastrointestinal motility Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
The invention discloses a new piperazinylbenzothiazole derivative, 2-[1-(4-piperonyl)piperazinyl]benzothiazole, having the formula (I) and pharmaceutically acceptable salts thereof, the processes for its preparation, its application as agents for stimulating gastrointestinal motility, and pharmaceutical compositions containing said derivative.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09300493A ES2062940B1 (en) | 1993-03-11 | 1993-03-11 | GASTROCINETIC AGENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT. |
| PCT/ES1994/000021 WO1994020494A1 (en) | 1993-03-11 | 1994-03-03 | Gastrokinetic agent, process for its preparation and pharmaceutical compositions containing said agent |
| AU62085/94A AU6208594A (en) | 1993-03-11 | 1994-03-03 | Gastrokinetic agent, process for its preparation and pharmaceutical compositions containing said agent |
| ZA941673A ZA941673B (en) | 1993-03-11 | 1994-04-10 | A gastrokinetic agent its method of preparation and pharmaceutical compositions containing it |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09300493A ES2062940B1 (en) | 1993-03-11 | 1993-03-11 | GASTROCINETIC AGENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2062940A1 true ES2062940A1 (en) | 1994-12-16 |
| ES2062940B1 ES2062940B1 (en) | 1995-06-16 |
Family
ID=8281067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09300493A Expired - Fee Related ES2062940B1 (en) | 1993-03-11 | 1993-03-11 | GASTROCINETIC AGENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT. |
Country Status (4)
| Country | Link |
|---|---|
| AU (1) | AU6208594A (en) |
| ES (1) | ES2062940B1 (en) |
| WO (1) | WO1994020494A1 (en) |
| ZA (1) | ZA941673B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4832699A (en) * | 1998-06-30 | 2000-01-17 | Neurogen Corporation | 1-(benzothiazol-2-yl)-4-(1-phenylmethyl)piperazines: dopamine receptor subtype specific ligands |
| US6291463B1 (en) | 1998-06-30 | 2001-09-18 | Neurogen Corporation | 1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1187680A (en) * | 1967-11-15 | 1970-04-15 | Science Union & Cie | New Heterocyclic Substituted Piperazines |
| ES411984A1 (en) * | 1972-02-29 | 1976-06-16 | Pierrel Spa | Nitrogen containing isoprenoid compounds |
| ES439870A3 (en) * | 1975-07-31 | 1977-03-16 | Rocador Sa | Procedure for the obtaining of new amides of piperonil-piperazine. (Machine-translation by Google Translate, not legally binding) |
| ES453269A1 (en) * | 1976-11-12 | 1977-11-16 | Boehringer Mannheim Gmbh | PROCEDURE FOR OBTAINING N-3,4-METHYLEDIOXYBENZYL-N '3, 7, 11-TRIMETHYL 2, 6, 10-DODECATRIENYLPIPERAZINE. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1595923A1 (en) * | 1965-02-20 | 1969-11-27 | Merck Ag E | 1-Aralkyl-4- (thiazolyl-2) -piperazines and processes for their preparation |
-
1993
- 1993-03-11 ES ES09300493A patent/ES2062940B1/en not_active Expired - Fee Related
-
1994
- 1994-03-03 WO PCT/ES1994/000021 patent/WO1994020494A1/en not_active Ceased
- 1994-03-03 AU AU62085/94A patent/AU6208594A/en not_active Abandoned
- 1994-04-10 ZA ZA941673A patent/ZA941673B/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1187680A (en) * | 1967-11-15 | 1970-04-15 | Science Union & Cie | New Heterocyclic Substituted Piperazines |
| ES411984A1 (en) * | 1972-02-29 | 1976-06-16 | Pierrel Spa | Nitrogen containing isoprenoid compounds |
| ES439870A3 (en) * | 1975-07-31 | 1977-03-16 | Rocador Sa | Procedure for the obtaining of new amides of piperonil-piperazine. (Machine-translation by Google Translate, not legally binding) |
| ES453269A1 (en) * | 1976-11-12 | 1977-11-16 | Boehringer Mannheim Gmbh | PROCEDURE FOR OBTAINING N-3,4-METHYLEDIOXYBENZYL-N '3, 7, 11-TRIMETHYL 2, 6, 10-DODECATRIENYLPIPERAZINE. |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA941673B (en) | 1994-10-12 |
| ES2062940B1 (en) | 1995-06-16 |
| AU6208594A (en) | 1994-09-26 |
| WO1994020494A1 (en) | 1994-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991102 |