ES2063015T3 - Proceso para la produccion de nuevos antibioticos, benanomicinas a y b y dexilosilbenanomicina b y usos de los mismos. - Google Patents

Proceso para la produccion de nuevos antibioticos, benanomicinas a y b y dexilosilbenanomicina b y usos de los mismos.

Info

Publication number
ES2063015T3
ES2063015T3 ES88118253T ES88118253T ES2063015T3 ES 2063015 T3 ES2063015 T3 ES 2063015T3 ES 88118253 T ES88118253 T ES 88118253T ES 88118253 T ES88118253 T ES 88118253T ES 2063015 T3 ES2063015 T3 ES 2063015T3
Authority
ES
Spain
Prior art keywords
benanomycines
new
dexylosylbenanomycin
production
new antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88118253T
Other languages
English (en)
Inventor
Tomio Takeuchi
Takeshi Hara
Masa Hamada
Shinichi Kondo
Masaji Sezaki
Haruo Yamamoto
Shuichi Gomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP62277692A external-priority patent/JP2592468B2/ja
Priority claimed from JP32716387A external-priority patent/JP2512050B2/ja
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Application granted granted Critical
Publication of ES2063015T3 publication Critical patent/ES2063015T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/826—Actinomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

DOS NUEVOS ANTIBIOTICOS QUE HAN SIDO LLAMADOS BENANOMICINAS A Y B RESPECTIVAMENTE SON PRODUCIDOS POR FERMENTACION MEDIANTE EL CULTIVO DE UN NUEVO MICFROORGANISMO, DENOMINADO COMO CEPA MH193 16F4 DE ACTINIMICETES. LAS BENANOMICINAS A Y B MUETRAN CADA UNA ACTIVIDAD ANTIFUNGICA Y SON UTILES COMO AGENTES TERAPEUTICOS ANTIFUNGICOS. UN NUEVO COMPUESTO DECXILLOSXILBENANOMICINA B SE PRODUCE AHORA POR CONVERSION QUIMICA DEL BENANOMICINA B, Y ESTE ANTIBIOTICO SEMISINTETICO TAMBIEN MUESTRA ACTIVIDAD ANTIFUNGICA Y ES UTIL COMO AGENTE TERAPEUTICO ANTIFUNGICO.
ES88118253T 1987-11-02 1988-11-02 Proceso para la produccion de nuevos antibioticos, benanomicinas a y b y dexilosilbenanomicina b y usos de los mismos. Expired - Lifetime ES2063015T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP62277692A JP2592468B2 (ja) 1987-11-02 1987-11-02 新規抗生物質ベナノマイシンａおよびｂならびにその製造法
JP32716387A JP2512050B2 (ja) 1987-12-25 1987-12-25 新規抗かび性抗生物質デキシロシルベナノマイシンｂならびにその製造法

Publications (1)

Publication Number Publication Date
ES2063015T3 true ES2063015T3 (es) 1995-01-01

Family

ID=26552521

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88118253T Expired - Lifetime ES2063015T3 (es) 1987-11-02 1988-11-02 Proceso para la produccion de nuevos antibioticos, benanomicinas a y b y dexilosilbenanomicina b y usos de los mismos.

Country Status (10)

Country Link
US (2) US5055453A (es)
EP (1) EP0315147B1 (es)
AR (1) AR241657A1 (es)
AU (1) AU612189B2 (es)
CA (1) CA1339016C (es)
DE (1) DE3887820T2 (es)
DK (1) DK170029B1 (es)
ES (1) ES2063015T3 (es)
FI (1) FI98739C (es)
MX (1) MX9201563A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110960A (en) * 1987-02-02 1992-05-05 Bristol-Myers Company Antifungal antibiotics
US4990497A (en) * 1987-02-02 1991-02-05 Toshikazu Oki Antifungal antibiotics
US5109122A (en) * 1987-11-02 1992-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antibiotics, dexylosylbenanomicin B
US4992425A (en) * 1988-06-07 1991-02-12 Bristol-Myers Company Antibiotics BU-3608D and BU-3608E
US4960755A (en) * 1988-07-19 1990-10-02 Bristol-Myers Company BU-3608 derivatives
JP2643340B2 (ja) * 1988-08-22 1997-08-20 財団法人微生物化学研究会 ヒト後天性免疫不全症候群ウイルス感染阻害剤
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
DE69009923T2 (de) * 1989-09-26 1994-11-03 Zaidan Hojin Biseibutsu Antifungales Antibiotikum und seine Herstellung und Verwendung.
FI92207C (fi) * 1989-11-14 1994-10-10 Squibb Bristol Myers Co Menetelmä terapeuttisesti käyttökelpoisten pradimisiinijohdannaisten valmistamiseksi
US5227370A (en) * 1989-11-14 1993-07-13 Bristol-Myers Squibb Company Pradimicin derivatives
CA2162186C (en) * 1989-11-22 1998-12-15 Shimpei Aburaki Pradimicin derivatives
US5217877A (en) * 1990-09-28 1993-06-08 Bristol-Myers Squibb Company Process for the preparation of α-glucosidase inhibitor, pradimicin Q
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
US5091418A (en) * 1990-09-28 1992-02-25 Bristol-Myers Squibb Company Novel alpha-glucosidase inhibitor, pradimicin Q
JP3134010B2 (ja) * 1991-11-26 2001-02-13 財団法人微生物化学研究会 デスアラニンベナノマイシンａ誘導体およびそれらの製造法
US5837828A (en) * 1992-04-08 1998-11-17 Bristol-Myers Squibb Co. Pradimicin derivatives
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
DK1934327T3 (da) * 2005-09-13 2013-04-15 Organobalance Gmbh Mikroorganismer, der hæmmer dannelsen af armhulelugt
JP5020245B2 (ja) * 2005-09-19 2012-09-05 ビーエーエスエフ ソシエタス・ヨーロピア 足臭の形成を阻害する微生物
US9877494B2 (en) * 2014-08-21 2018-01-30 Shantung HSU Active fermentation process and fermented liquid and drinks made by using the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870165A (en) * 1987-02-02 1989-09-26 Bristol-Myers Company Antifungal antibiotics

Also Published As

Publication number Publication date
AR241657A1 (es) 1992-10-30
FI98739C (fi) 1997-08-11
FI98739B (fi) 1997-04-30
DK608288D0 (da) 1988-11-01
AU612189B2 (en) 1991-07-04
FI885039L (fi) 1989-05-03
MX9201563A (es) 1993-10-01
DE3887820T2 (de) 1994-05-19
US5278052A (en) 1994-01-11
DE3887820D1 (de) 1994-03-24
AU2457988A (en) 1989-05-25
CA1339016C (en) 1997-03-25
DK608288A (da) 1989-05-03
EP0315147A2 (en) 1989-05-10
FI885039A0 (fi) 1988-11-01
EP0315147B1 (en) 1994-02-16
EP0315147A3 (en) 1991-05-15
US5055453A (en) 1991-10-08
DK170029B1 (da) 1995-05-01

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