ES2063264T3 - Oxazolidinonas fungicidas. - Google Patents

Oxazolidinonas fungicidas.

Info

Publication number
ES2063264T3
ES2063264T3 ES90303859T ES90303859T ES2063264T3 ES 2063264 T3 ES2063264 T3 ES 2063264T3 ES 90303859 T ES90303859 T ES 90303859T ES 90303859 T ES90303859 T ES 90303859T ES 2063264 T3 ES2063264 T3 ES 2063264T3
Authority
ES
Spain
Prior art keywords
substituted
ring
alkyl
phenyl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90303859T
Other languages
English (en)
Inventor
Detlef Gefften
Dennis Raymond Rayner
John Benjamin J Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26992641&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2063264(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/341,741 external-priority patent/US4957933A/en
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of ES2063264T3 publication Critical patent/ES2063264T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/761,3-Oxazoles; Hydrogenated 1,3-oxazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/46Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un procedimiento para reprimir enfermedades por hongos en plantas que comprende el tratamiento del lugar que se va a protegar con una cantidad efectiva de un compuesto de Fórmula I. en la que: A esOoNR 4 ; W esOoS; R 1 es H; C1 a C6 alquilo; C1 a C6 haloalquilo; C3 a C6 cicloalquilo; C2 a C6 alquenilo; C2 a C6 alquinilo; C2 a C6 alcoxialquilo; C1 a C3 alquilo sustituido con C3 a C6 cicloalquilo, fenilo o bencilo, en donde dicho anillo de fenilo o bencilo está sustituido en el anillo con R 6 , y el carbono bencílico está sustituido con R 7 ; R 2 es fenilo sustituido con R 5 y R 6 ; naftilo sustituido con 1 ó 2 grupos seleccionados de R 6 ; tienilo sustituido con R 5 y R 6 ; furilo sustituido con R 6 ; piridilo sustituido con uno de los siguientes: R 6 ; fenoxi sustituido con R 6 , o feniltio sustituido con R 6 ; C1 a C2 alquilo sustituido con fenoxi o feniltio, estando sustituidos dichos fenoxi o feniltio en el anillo con R 6 ; C1 a C6 alquilo; o C5 a C7 cicloalquilo; y R 1 y R 2 pueden tomarse conjuntamente, junto al carbono al que están unidos, para formar un anillo carbocíclico o heterocíclico (conteniendo O, N-R 7 ,oS)de5 a 7 átomos en el anillo en que el anillo heterocíclico puede estar fusionado con un anillo bencénico sustituido con R 5 o un anillo de tiofeno sustituido con R 6 , no estando unido el heteroátomo al centro espiro; y el anillo carbocíclico puede estar fusionado con 1 o 2 anillos bencénicos sustituidos con R 5 o con un anillo de tiofeno sustituido con R 6 ; R 3 es fenilo sustituido con R 10 ; bencilo sustituido en el carbono bencílico con un grupo seleccionado de R 7 y sustituido en el anillo de fenilo con R 10 ; naftilo sustituido con R 10 ; adicionalmente, R 3 puede ser tienilo sustituido con R 10 , furilo sustituido con R 10 , piridilo sustituido con R 10 , pirimidilo sustituido con R 10 , o piridazilo sustituido con R 10 ; oR 3 puede ser C2 a C10 alquilo o C5 a C7 cicloalquilo; R 4 es hidrógeno; formilo; C2 a C4 alquilcarbonilo; C2 a C4 haloalquilcarbonilo; C2 a C4 alcoxialquilcarbonilo; C2 a C4 alcoxicarbonilo; C2 a C5 alquilaminocarbonilo; C1 a C4 alquilsulfonilo; C1 a C4 alquilo; C4 a C6 cicloalquilo; fenilaminocarbonilo donde dicho fenilo está sustituido con R 10 ; yR 4 puede ser C3 a C4 alquenilo o C3 a C4 alquinilo; o R 3 y R 4 pueden tomarse conjuntamente, junto con el átomo de nitrógeno al que están unidos, para formar un anillo de pirrolidina, piperidina o pirrol sustituidos con R 10 , anillos que pueden estar fusionados a un anillo bencénico sustituido con R 10 ; R 5 es hidrógeno, halógeno, C1 a C12 alquilo; C1 a C12 haloalquilo; C1 a C12 alcoxi; C3 a C12 alquenilo; C3 a C12 haloalquenilo; C3 a C12 alqueniloxi; C3 a C12 alquinilo; C3 a C12 haloalquinilo; C3 a C12 alquiltio; C1 a C12 haloalquiltio; C1 a C12 haloalcoxi; C1 a C12 alquilsulfonilo; C1 a C12 haloalquilsulfonilo; nitro; fenilo sustituido con R 6 ; fenoxi sustituidoconR 6 ; feniltio sustituido con R 6 ; ciano;C3 a C12 alquiniloxi; C2 a C12 alcoxialquilo; C2 a C12 alcoxialcoxi; fenoximetilo sustituido en el anillo de fenilo con R 6 ; benciloxi sustituido en el anillo de fenilo con R 6 ; fenetiloxi sustituido en el anillo de fenilo con R 6 ; fenetilo sustituido en el anillo de fenilo con R 6 ; bencilo sustituido en el anillo de fenilo con R 6 ; C2 a C12 carboalcoxi; C5 a C6 cicloalquilo; NMe2; oNR 8 R 9 ; R 6 es hidrógeno; 1 a 2 halógenos; C1 a C4 alquilo; tri uorometilo; C1 a C4 alcoxi; metiltio; nitro; fenoxi; C2 a C6 cicloalquiloxi; o C6 a C6 cicloalquilo; R 7 es hidrógeno; o C1 a C4 alquilo; R 8 es H; o C1 a C4 alquilo; R 9 es H; fenilo sustituido con H; 1-2 halógenos; CF3; C1 a C2 alquilo; o C1 a C2 alcoxi; y R 10 es 0-2 grupos seleccionados de CF3; CF3O; NO2; CO2Me; halógeno; C1 a C5 alquilo; C1 a C5 alcoxi; o CN; a condición de que cuando el anillo R 3 es disustituido, uno de los grupos R 10 alquilo o alcoxi no son superiores a C1; con la condición de que, cuando A es oxígeno, R 3 es fenilo sustituido con R 10 .
ES90303859T 1989-04-21 1990-04-10 Oxazolidinonas fungicidas. Expired - Lifetime ES2063264T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34174289A 1989-04-21 1989-04-21
US07/341,741 US4957933A (en) 1989-04-21 1989-04-21 Fungicidal oxazolidinones

Publications (1)

Publication Number Publication Date
ES2063264T3 true ES2063264T3 (es) 1995-01-01

Family

ID=26992641

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90303859T Expired - Lifetime ES2063264T3 (es) 1989-04-21 1990-04-10 Oxazolidinonas fungicidas.

Country Status (24)

Country Link
EP (2) EP0393911B1 (es)
JP (1) JP2963388B2 (es)
KR (1) KR0148128B1 (es)
CN (2) CN1028143C (es)
AT (1) ATE110719T1 (es)
AU (1) AU638460B2 (es)
BG (1) BG60677B1 (es)
BR (1) BR9007309A (es)
CZ (1) CZ286037B6 (es)
DE (2) DE69011930T2 (es)
DK (1) DK0393911T3 (es)
ES (1) ES2063264T3 (es)
FI (1) FI914927A0 (es)
HU (1) HU214551B (es)
IE (1) IE66407B1 (es)
IL (1) IL94152A (es)
NL (1) NL350010I2 (es)
NO (1) NO914117L (es)
NZ (1) NZ233374A (es)
RO (1) RO111765B1 (es)
RU (1) RU2092051C1 (es)
UA (1) UA35548C2 (es)
WO (1) WO1990012791A1 (es)
YU (1) YU80390A (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019703A2 (en) * 1990-06-11 1991-12-26 E.I. Du Pont De Nemours And Company Fungicidal iminooxazolidinones
WO1992016515A1 (en) * 1991-03-15 1992-10-01 E.I. Du Pont De Nemours And Company Fungicidal 4-thioxooxazolidin-2-ones and 4-iminooxazolindin-2-ones
AU647599B2 (en) * 1991-03-27 1994-03-24 Sankyo Company Limited New thiazolidinone and oxazolidinone derivatives, their preparation and their use as vasodilators
FR2685328B1 (fr) * 1991-12-20 1995-12-01 Rhone Poulenc Agrochimie Derives de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides.
WO1993018016A1 (en) * 1992-03-11 1993-09-16 E.I. Du Pont De Nemours And Company Fungicidal oxazolidinones
WO1993022299A1 (en) * 1992-04-24 1993-11-11 E.I. Du Pont De Nemours And Company Fungicidal oxazolidinones
EP0642502B1 (en) * 1992-05-22 2000-07-12 E.I. Du Pont De Nemours And Company Fungicidal imidazolinones
HU215699B (hu) * 1992-11-13 1999-02-01 E. I. Du Pont De Nemours And Co. Eljárás 2,4-oxazolidin-dionok és intermedierjeik előállítására
HUP9800413A3 (en) * 1995-03-08 1998-07-28 Du Pont Fungicide composition containing 5-methyl-5-(4-phenoxyphenyl)-3-phenylamino-2,4-oxazolidinedione and triazole-derivative compound as active ingredients and use thereof
CZ296513B6 (cs) * 1995-07-12 2006-03-15 E. I. Du Pont De Nemours And Company Synergická fungicidní kompozice
GB9607784D0 (en) * 1996-04-15 1996-06-19 Zeneca Ltd Fungicides
GB9607785D0 (en) * 1996-04-15 1996-06-19 Zeneca Ltd Fungicides
CA2280809C (en) * 1997-03-05 2007-04-24 Novartis Ag Fungicidal compositions based on metalyxyl
FR2771898B1 (fr) * 1997-12-04 2000-01-07 Rhone Poulenc Agrochimie Composition fongicide et/ou bactericide synergique
US6090806A (en) * 1998-08-31 2000-07-18 American Cyanamid Company Fungicidal mixtures
DE10347090A1 (de) 2003-10-10 2005-05-04 Bayer Cropscience Ag Synergistische fungizide Wirkstoffkombinationen
DE10349501A1 (de) 2003-10-23 2005-05-25 Bayer Cropscience Ag Synergistische fungizide Wirkstoffkombinationen
DE102004021532A1 (de) * 2004-05-03 2005-12-08 Degussa Ag Dispersion mit insektizider Wirkung
DE102005015677A1 (de) 2005-04-06 2006-10-12 Bayer Cropscience Ag Synergistische fungizide Wirkstoffkombinationen
DE102005026482A1 (de) 2005-06-09 2006-12-14 Bayer Cropscience Ag Wirkstoffkombinationen
EA201270781A1 (ru) 2005-06-09 2013-09-30 Байер Кропсайенс Аг Комбинации биологически активных веществ
DE102007045920B4 (de) 2007-09-26 2018-07-05 Bayer Intellectual Property Gmbh Synergistische Wirkstoffkombinationen
CN101555207B (zh) * 2008-04-10 2012-10-17 上海生农生化制品有限公司 一种对苯氧基苯基乳酸酯化高收率的方法
MX2011009732A (es) 2009-03-25 2011-09-29 Bayer Cropscience Ag Combinaciones de principios activos sinergicas.
KR20120051015A (ko) 2009-07-16 2012-05-21 바이엘 크롭사이언스 아게 페닐 트리아졸을 함유하는 상승적 활성 물질 배합물
CN103396410A (zh) * 2013-08-07 2013-11-20 北京金五元科技发展有限责任公司 吡噁唑菌酮的合成及作为农用杀菌剂的应用
CN104472502A (zh) * 2014-11-27 2015-04-01 广东中迅农科股份有限公司 一种含有噁唑菌酮和咯菌腈的杀菌组合物
CN104488888A (zh) * 2014-12-03 2015-04-08 广东中迅农科股份有限公司 一种含有噁唑菌酮和苯锈啶的杀菌组合物
EP2910126A1 (en) 2015-05-05 2015-08-26 Bayer CropScience AG Active compound combinations having insecticidal properties
CN105541743A (zh) * 2015-12-10 2016-05-04 上海生农生化制品有限公司 一种双联类噁唑菌酮化合物及其合成方法
CN107540626A (zh) * 2016-06-23 2018-01-05 华东理工大学 噁唑菌酮的多晶型及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2037717A (en) * 1932-11-09 1936-04-21 Du Pont Xanthates and method of making same
US2891855A (en) 1954-08-16 1959-06-23 Geigy Ag J R Compositions and methods for influencing the growth of plants
US3054794A (en) * 1958-01-17 1962-09-18 Us Vitamin Pharm Corp Process for preparing 3-(aminoalkyl)-oxazolidine-2, 4-diones
US2928840A (en) * 1958-11-26 1960-03-15 Us Vitamin Pharm Corp 3-(o-substituted phenyl) oxazolidinediones and process therefor
US3235361A (en) 1962-10-29 1966-02-15 Du Pont Method for the control of undesirable vegetation
US3309192A (en) 1964-12-02 1967-03-14 Du Pont Method of controlling seedling weed grasses
US3773782A (en) * 1971-10-18 1973-11-20 J Zielinski Thiophosphates of acylated 3-amino-2-oxazolidones
DE2324591C2 (de) * 1973-05-16 1985-12-12 Basf Ag, 6700 Ludwigshafen Oxazolidin-Derivate
US4150144A (en) * 1977-02-15 1979-04-17 Ciba-Geigy Corporation 3-Phenyl-oxazolidine-2,4-dione microbicides
DE3682275D1 (de) * 1985-10-11 1991-12-05 Sagami Chem Res Oxazolidindionabkoemmlinge, deren herstellungsverfahren und unkrautvertilgungsmittel, die diese enthalten.
GB8612630D0 (en) 1986-05-23 1986-07-02 Ici Plc Biocides
US4957933A (en) 1989-04-21 1990-09-18 E. I. Du Pont De Nemours And Company Fungicidal oxazolidinones
ES2224428T3 (es) 1997-09-26 2005-03-01 Celltech Pharma Europe Limited Composicion farmnaceutica para el tratamiento de la enfermedad inflmatoria intestinal.

Also Published As

Publication number Publication date
KR0148128B1 (ko) 1998-08-17
EP0469061A1 (en) 1992-02-05
JPH09104677A (ja) 1997-04-22
RO111765B1 (ro) 1997-01-30
CZ286037B6 (cs) 1999-12-15
CN1058841C (zh) 2000-11-29
BG95344A (bg) 1993-12-24
NO914117L (no) 1991-11-29
AU5655490A (en) 1990-11-16
BG60677B1 (en) 1995-12-29
HUT60255A (en) 1992-08-28
JP2963388B2 (ja) 1999-10-18
DK0393911T3 (da) 1994-10-03
WO1990012791A1 (en) 1990-11-01
HU904470D0 (en) 1991-12-30
RU2092051C1 (ru) 1997-10-10
HU214551B (hu) 1998-08-28
CZ198490A3 (cs) 1999-10-13
UA35548C2 (uk) 2001-04-16
NL350010I1 (nl) 2003-04-01
ATE110719T1 (de) 1994-09-15
BR9007309A (pt) 1992-03-24
FI914927A7 (fi) 1991-10-18
EP0393911B1 (en) 1994-08-31
FI914927A0 (fi) 1991-10-18
IL94152A (en) 1995-08-31
YU80390A (en) 1991-10-31
EP0393911A1 (en) 1990-10-24
AU638460B2 (en) 1993-07-01
DE69011930D1 (de) 1994-10-06
KR920701179A (ko) 1992-08-11
IE66407B1 (en) 1995-12-27
CN1047079A (zh) 1990-11-21
NO914117D0 (no) 1991-10-18
DE69011930T2 (de) 1995-01-19
IE901410L (en) 1990-10-21
NZ233374A (en) 1991-02-26
DE10199034I2 (de) 2011-07-21
CN1096157A (zh) 1994-12-14
NL350010I2 (nl) 2004-01-05
CN1028143C (zh) 1995-04-12

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