ES2064919T3 - Derivados del acido bifenil 5,5'-bis-alcanoico, su fabricacion y utilizacion. - Google Patents

Derivados del acido bifenil 5,5'-bis-alcanoico, su fabricacion y utilizacion.

Info

Publication number
ES2064919T3
ES2064919T3 ES91307270T ES91307270T ES2064919T3 ES 2064919 T3 ES2064919 T3 ES 2064919T3 ES 91307270 T ES91307270 T ES 91307270T ES 91307270 T ES91307270 T ES 91307270T ES 2064919 T3 ES2064919 T3 ES 2064919T3
Authority
ES
Spain
Prior art keywords
alcanoic
bis
derivatives
manufacture
biphenyl acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91307270T
Other languages
English (en)
Inventor
Yukio Suzuki
Kouichi Kuno
Motoshi Shoda
Masao Yaso
Satoshi Yaginuma
Akira Asahi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Application granted granted Critical
Publication of ES2064919T3 publication Critical patent/ES2064919T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN COMPUESTO DE FORMULA (I): EN EL CUAL R ES UN ALQUILO C SUB 1-12; ALQUILULO EN DONDE X SUB 1 Y X SUB 2, QUE PUEDEN SER LO MISMO O DIFERENTE, SON CADA UNO HIDROGENO O UN HALOGENO; CICLOHEXILMETILO; CICLOHEXIL; TETRAHIDRO -2H-PIRAN-1-YL-METILO; CARBOXY ALQUILULO O CLORO ALQUILULO, Y CADA N, QUE PUEDE SER LO MISMO O DIFERENTE, ES 2 O 3, O UNA SAL FISIOLOGICAMENTE ACEPTABLE DE LO MISMO.
ES91307270T 1990-08-08 1991-08-08 Derivados del acido bifenil 5,5'-bis-alcanoico, su fabricacion y utilizacion. Expired - Lifetime ES2064919T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2208127A JPH0495049A (ja) 1990-08-08 1990-08-08 ビフェニル‐５，５’‐ビス‐アルカン酸誘導体、その製造法およびその用途

Publications (1)

Publication Number Publication Date
ES2064919T3 true ES2064919T3 (es) 1995-02-01

Family

ID=16551089

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91307270T Expired - Lifetime ES2064919T3 (es) 1990-08-08 1991-08-08 Derivados del acido bifenil 5,5'-bis-alcanoico, su fabricacion y utilizacion.

Country Status (6)

Country Link
US (1) US5136090A (es)
EP (1) EP0470832B1 (es)
JP (1) JPH0495049A (es)
AT (1) ATE115537T1 (es)
DE (1) DE69105865T2 (es)
ES (1) ES2064919T3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999019291A1 (en) 1997-10-14 1999-04-22 Asahi Kasei Kogyo Kabushiki Kaisha Biphenyl-5-alkanoic acid derivatives and use thereof
GB9827391D0 (en) * 1998-12-11 1999-02-03 Fundation O N C F Aldose reductase inhibitors and pharmaceutical compositions
MXPA03011558A (es) 2001-06-12 2004-03-26 Wellstat Therapeutics Corp Compuestos para el tratamiento de desordenes metabolicos.
US6867320B2 (en) * 2002-02-21 2005-03-15 Asahi Kasei Pharma Corporation Substituted phenylalkanoic acid derivatives and use thereof
US7470807B2 (en) * 2003-08-14 2008-12-30 Asahi Kasei Pharma Corporation Substituted arylalkanoic acid derivatives and use thereof
CA2820931C (en) 2006-07-20 2015-08-18 Asahi Kasei Pharma Corporation Novel crystals of substituted phenylalkanoic acid and method of producing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62205095A (ja) * 1986-03-04 1987-09-09 Toyo Jozo Co Ltd 新生理活性物質アルドスタチンおよびその製造法
JPH0272144A (ja) * 1988-09-06 1990-03-12 Fujisawa Pharmaceut Co Ltd Ｆｒ９００２８０物質およびその製造法

Also Published As

Publication number Publication date
EP0470832A2 (en) 1992-02-12
JPH0495049A (ja) 1992-03-27
EP0470832A3 (en) 1992-11-19
EP0470832B1 (en) 1994-12-14
ATE115537T1 (de) 1994-12-15
DE69105865D1 (de) 1995-01-26
US5136090A (en) 1992-08-04
DE69105865T2 (de) 1995-05-18

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