ES2066522T3 - Nuevos derivados de acidos p-oxibenzoicos, procedimiento para su preparacion y su utilizacion como medicamentos. - Google Patents

Nuevos derivados de acidos p-oxibenzoicos, procedimiento para su preparacion y su utilizacion como medicamentos.

Info

Publication number
ES2066522T3
ES2066522T3 ES92110602T ES92110602T ES2066522T3 ES 2066522 T3 ES2066522 T3 ES 2066522T3 ES 92110602 T ES92110602 T ES 92110602T ES 92110602 T ES92110602 T ES 92110602T ES 2066522 T3 ES2066522 T3 ES 2066522T3
Authority
ES
Spain
Prior art keywords
medicines
procedure
preparation
new derivatives
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92110602T
Other languages
English (en)
Inventor
Fiedemann Dr Dipl-Chem Reiter
Helmut Dr Dipl-Chem Grill
Hans-Helmut Henschel
Michael Schliack
Klaus Prof Dr Seibel
Roland Dr Loser
Gerhard Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Deutschland GmbH
Original Assignee
Klinge Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Pharma GmbH and Co filed Critical Klinge Pharma GmbH and Co
Application granted granted Critical
Publication of ES2066522T3 publication Critical patent/ES2066522T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A DERIVADOS DEL ACIDO OXIBENZOICO-P DE LA FORMULA GENERAL (1) EN LA QUE SIGNIFICAN: R1 = Y R2 = OH, SUS DIAESTEREOMEROS Y ENANTIOMEROS EN FORMA PURA O COMO MEZCLA DE FORMAS ESTEREOISOMERA, ASI COMO SUS SALES TOLERABLES FISIOLOGICAMENTE, UN METODO PARA SU FABRICACION, ASI COMO SU EMPLEO PARA LA FABRICACION DE PRODUCTOS FARMACEUTICOS CON ACCION HIPOLIPEMICO.
ES92110602T 1991-08-22 1992-06-24 Nuevos derivados de acidos p-oxibenzoicos, procedimiento para su preparacion y su utilizacion como medicamentos. Expired - Lifetime ES2066522T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4127800A DE4127800A1 (de) 1991-08-22 1991-08-22 Neue p-oxibenzoesaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES2066522T3 true ES2066522T3 (es) 1995-03-01

Family

ID=6438847

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92110602T Expired - Lifetime ES2066522T3 (es) 1991-08-22 1992-06-24 Nuevos derivados de acidos p-oxibenzoicos, procedimiento para su preparacion y su utilizacion como medicamentos.

Country Status (9)

Country Link
US (1) US5149865A (es)
EP (1) EP0529226B1 (es)
JP (1) JPH07113002B2 (es)
AT (1) ATE116282T1 (es)
DE (2) DE4127800A1 (es)
DK (1) DK0529226T3 (es)
EE (1) EE02939B1 (es)
ES (1) ES2066522T3 (es)
GR (1) GR3015467T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10331924B2 (en) 2016-12-14 2019-06-25 Reliant Immune Diagnostics, Inc. System and method for audiovisual response to retail diagnostic product

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642867A (en) * 1968-04-26 1972-02-15 Asahi Chemical Ind Process for the preparation of a 1 2-bis(4-carboalkoxyphenoxy)ethane
US4067892A (en) * 1973-08-23 1978-01-10 Beecham Group Limited Substituted (4-carboxyphenoxy) phenyl alkane compounds
DE2460689C3 (de) * 1974-12-20 1980-06-26 Klinge Pharma Gmbh & Co, 8000 Muenchen 13-disubstituierte Propanol-(2)-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB1551416A (en) * 1976-08-27 1979-08-30 Beecham Group Ltd Long chain dioxy hypolipidaemics
DE3326164A1 (de) * 1983-07-20 1985-01-31 Klinge Pharma GmbH, 8000 München Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4778925A (en) * 1985-12-30 1988-10-18 Klinge Pharma Gmbh New benzoic acid derivatives, as well as processes for their production and their use as pharmaceuticals
US4713472A (en) * 1986-05-15 1987-12-15 Eastman Kodak Company Preparation of dimethyl 4,4'-stilbenedicarboxylate and intermediates therefor
JP2700522B2 (ja) * 1993-06-18 1998-01-21 三菱化工機株式会社 汚泥脱水用デカンタ

Also Published As

Publication number Publication date
EP0529226A1 (de) 1993-03-03
EP0529226B1 (de) 1994-12-28
ATE116282T1 (de) 1995-01-15
EE02939B1 (et) 1996-08-15
DK0529226T3 (da) 1995-05-29
JPH07113002B2 (ja) 1995-12-06
US5149865A (en) 1992-09-22
DE4127800A1 (de) 1993-02-25
DE59201085D1 (de) 1995-02-09
GR3015467T3 (en) 1995-06-30
JPH05194316A (ja) 1993-08-03

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