ES2067024T3 - Metodo y kit para determinar actividades fosforilantes y desfosforilantes de tirosina. - Google Patents

Metodo y kit para determinar actividades fosforilantes y desfosforilantes de tirosina.

Info

Publication number
ES2067024T3
ES2067024T3 ES90904448T ES90904448T ES2067024T3 ES 2067024 T3 ES2067024 T3 ES 2067024T3 ES 90904448 T ES90904448 T ES 90904448T ES 90904448 T ES90904448 T ES 90904448T ES 2067024 T3 ES2067024 T3 ES 2067024T3
Authority
ES
Spain
Prior art keywords
kit
polypeptide
phosphorilant
dephosphorifying
thyrosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90904448T
Other languages
English (en)
Inventor
Gerrit Rijksen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FERRING NV
Original Assignee
FERRING NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FERRING NV filed Critical FERRING NV
Application granted granted Critical
Publication of ES2067024T3 publication Critical patent/ES2067024T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

ES UN METODO SEGURO Y EFICIENTE PARA DETERMINAR LA TIROSINA-FOSFORILATIN O LAS ACTIVIDADES FOSFOTIROSINA-DEFOSFORILATIN DE UNA SUSTANCIA, COMO POR EJEMPLO, UNA MUESTRA DE TEJIDO HUMANO, HACIENDO REACCIONAR LA MUESTRA CON UN POLIPEPTIDO QUE CONTIENE RESIDUOS DE (FOSFO)TIROSINA Y FOSFORILATO POLIPEPTIDO, UTILIZANDO UN ANTICUERPO CON UN POLIPEPTIDO QUE CONTIENE FOSFOTIROSINA. EL METODO PUEDE USARSE UTILIZANDO UN MALETIN DE DIAGNOSTICO QUE CONTIENE UN POLIPEPTIDO Y UN ANTICUERPO. EL METODO Y MALETIN SON UTILES PARA EL DIAGNOSTICO DE TUMORES.
ES90904448T 1989-03-03 1990-03-02 Metodo y kit para determinar actividades fosforilantes y desfosforilantes de tirosina. Expired - Lifetime ES2067024T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8900529A NL8900529A (nl) 1989-03-03 1989-03-03 Werkwijze en kit voor het bepalen van tyrosine fosforylerende en defosforylerende activiteit.

Publications (1)

Publication Number Publication Date
ES2067024T3 true ES2067024T3 (es) 1995-03-16

Family

ID=19854240

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90904448T Expired - Lifetime ES2067024T3 (es) 1989-03-03 1990-03-02 Metodo y kit para determinar actividades fosforilantes y desfosforilantes de tirosina.

Country Status (10)

Country Link
EP (1) EP0461174B1 (es)
JP (1) JP3208668B2 (es)
AT (1) ATE114193T1 (es)
AU (1) AU5263190A (es)
CA (1) CA2050317C (es)
DE (1) DE69014201T2 (es)
DK (1) DK0461174T3 (es)
ES (1) ES2067024T3 (es)
NL (1) NL8900529A (es)
WO (1) WO1990010234A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889150A (en) 1991-01-18 1999-03-30 New York University Medical Center Expression-cloning method for identifying target proteins for eukaryotic tyrosine kinases and novel target protiens
US5677421A (en) * 1991-01-18 1997-10-14 New York University Target proteins for eukaryotic tyrosine kinases
IE920151A1 (en) * 1991-01-18 1992-07-29 Univ New York A novel expression-cloning method for identifying target¹proteins for receptor tyrosine kinases and novel human grb¹proteins
WO1993003377A1 (en) * 1991-07-31 1993-02-18 Ziltener Hermann J Method for the detection of phosphotyrosine residues
DK0614530T3 (da) * 1991-11-15 1998-09-28 Cornell Res Foundation Inc Indirekte immunassay for dioxinlignende forbindelser
GB9314271D0 (en) * 1993-07-09 1993-08-18 Inst Of Cancer The Research Cell growth factor receptors
US6051397A (en) 1993-11-16 2000-04-18 Max Planck Gesellschaft Zur Forderung Der Wissenschaften DNA encoding MCK-10, a novel receptor tyrosine kinase
US5763198A (en) * 1994-07-22 1998-06-09 Sugen, Inc. Screening assays for compounds
EP0873142A4 (en) * 1995-06-07 2001-08-08 Sugen Inc CONNECTION TESTING TESTS
JP2000325086A (ja) * 1999-05-21 2000-11-28 Igaku Seibutsugaku Kenkyusho:Kk リン酸化酵素活性の測定方法
US7736890B2 (en) 2003-12-31 2010-06-15 President And Fellows Of Harvard College Assay device and method
EP1662258A1 (en) * 2004-11-25 2006-05-31 Sirenade Pharmaceuticals AG A substrate free in vitro protein kinase assay
JP6537143B2 (ja) * 2013-05-16 2019-07-03 国立大学法人京都大学 癌の予後を診断する方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543439A (en) 1982-12-13 1985-09-24 Massachusetts Institute Of Technology Production and use of monoclonal antibodies to phosphotyrosine-containing proteins

Also Published As

Publication number Publication date
ATE114193T1 (de) 1994-12-15
AU5263190A (en) 1990-09-26
CA2050317A1 (en) 1990-09-04
DE69014201D1 (de) 1994-12-22
WO1990010234A1 (en) 1990-09-07
JPH04504171A (ja) 1992-07-23
CA2050317C (en) 2002-05-07
DK0461174T3 (da) 1995-05-01
JP3208668B2 (ja) 2001-09-17
EP0461174B1 (en) 1994-11-17
EP0461174A1 (en) 1991-12-18
DE69014201T2 (de) 1995-06-14
NL8900529A (nl) 1990-10-01

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