ES2067029T3 - Ensayo de hemoglobina glicosilada. - Google Patents

Ensayo de hemoglobina glicosilada.

Info

Publication number
ES2067029T3
ES2067029T3 ES90908231T ES90908231T ES2067029T3 ES 2067029 T3 ES2067029 T3 ES 2067029T3 ES 90908231 T ES90908231 T ES 90908231T ES 90908231 T ES90908231 T ES 90908231T ES 2067029 T3 ES2067029 T3 ES 2067029T3
Authority
ES
Spain
Prior art keywords
signal
haemoglobin
pct
bound
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90908231T
Other languages
English (en)
Inventor
Erling Sundrehagen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axis Biochemicals AS
Original Assignee
Axis Biochemicals AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axis Biochemicals AS filed Critical Axis Biochemicals AS
Application granted granted Critical
Publication of ES2067029T3 publication Critical patent/ES2067029T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCION PRESENTA UN METODO PARA ENSAYAR LA HEMOGLOBINA GLICOSILADA QUE SE ENCUENTRA EN UNA MUESTRA, EL CUAL CONSISTE EN LOS PASOS SIGUIENTES: A) SOMETER OPCIONALMENTE LA PRUEBA A UN PROCESO DE HEMOLISIS PARA LIBERAR CUALQUIER CELULA QUE PUEDA ESTAR UNIDA A LA HEMOGLOBINA; B) PONER EN CONTACTO DICHA MUESTRA O HEMOGLOBINA RECUPERADA DE DICHA MUESTRA SEGUN EL PASO (C) DE ABAJO CON MOLECULAS QUE FORMAN SEÑALES QUE CONTIENEN UN CONJUGADO DE UNO O MAS RESIDUOS DE HIDROXIBORILO O SALES DE LAS MISMAS, UNIDAS A UNA ETIQUETA FORMADORA DE SEÑALES; (C) SEPARAR LA HEMOGLOBINA GLICOSILADA Y NO GLICOSILADA Y CUALQUIERA DE LAS MOLECULAS UNIDAS A LA MISMA DE LA MUESTRA O DE LA MEZCLA DE REACCION DEL PASO (B) DE ARRIBA; Y (D) ENSAYAR LAS MOLECULAS QUE FORMAN SEÑALES ANTEDICHAS QUE SE HAN UNIDO A LA HEMOGLOBINA SEPARADA Y/O CUALQUIERA DE LAS MOLECULAS FORMADORAS DE SEÑALES QUE NO SE HAN UNIDO A LA HEMOGLOBINA; Y UN EQUIPO DE PRUEBAS ANALITICO PARA SER UTILIZADO CON EL METODO DE LA INVENCION. EL NUEVO ENSAYO DE LA INVENCION ES PARTICULARMENTE UTIL PARA LA DIAGNOSIS IN VITRO Y EL CONTROL DEL MELITO PARA LA DIABETES.
ES90908231T 1989-05-11 1990-05-11 Ensayo de hemoglobina glicosilada. Expired - Lifetime ES2067029T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO891929A NO891929D0 (no) 1989-01-04 1989-05-11 Nye komposisjoner med loeselige signalmolekyler for in vitro overvaaking av diabetes mellitus.

Publications (1)

Publication Number Publication Date
ES2067029T3 true ES2067029T3 (es) 1995-03-16

Family

ID=19892012

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90908231T Expired - Lifetime ES2067029T3 (es) 1989-05-11 1990-05-11 Ensayo de hemoglobina glicosilada.

Country Status (16)

Country Link
US (1) US5242842A (es)
EP (1) EP0471774B1 (es)
JP (1) JPH0812196B2 (es)
KR (1) KR960010697B1 (es)
AT (1) ATE117806T1 (es)
AU (1) AU642879B2 (es)
BR (1) BR9007357A (es)
CA (1) CA2055430C (es)
DE (1) DE69016423T2 (es)
DK (1) DK0471774T3 (es)
ES (1) ES2067029T3 (es)
FI (1) FI100437B (es)
HU (1) HU215181B (es)
NO (4) NO890029D0 (es)
RU (1) RU2111494C1 (es)
WO (1) WO1990013818A1 (es)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807747A (en) * 1989-06-13 1998-09-15 Clinical Innovations Limited Method and apparatus for determination of glycosylated protein
US5403745A (en) * 1990-04-27 1995-04-04 Genzyme Corporation Determination of analytes in biological fluids in the presence of substances interfering with assays therefor
US5135875A (en) * 1990-08-15 1992-08-04 Abbott Laboratories Protein precipitation reagent
GB9024771D0 (en) * 1990-11-14 1991-01-02 Axis Research Assay
GB9024775D0 (en) * 1990-11-14 1991-01-02 Axis Research Chemical compounds
DE4206932A1 (de) * 1992-03-05 1993-09-09 Boehringer Mannheim Gmbh Immunologische methode zur bestimmung eines haemoglobinderivates
JP3171681B2 (ja) 1992-08-11 2001-05-28 積水化学工業株式会社 糖化蛋白の測定方法
US5512451A (en) * 1993-04-01 1996-04-30 British Technology Group Limited Enhancement of chemiluminescent reactions
PT741734E (pt) * 1994-01-28 2001-09-28 Prolinx Inc Complexos de acido fenilboronico
US5852178A (en) * 1994-01-28 1998-12-22 Prolinx, Inc. Phenylboronic acid complexing reagents for conjugating biologically active molecules
US5777148A (en) * 1994-01-28 1998-07-07 Prolinx, Inc. Boronic compound complexing reagents and highly stable complexes
US5847192A (en) * 1994-01-28 1998-12-08 Prolinx, Inc. Boronic compound complexing reagents and complexes
US5837878A (en) * 1994-01-28 1998-11-17 Prolinx, Inc. Boronic compound complexing reagents and highly stable complexes
US5744627A (en) * 1994-01-28 1998-04-28 Prolinx, Inc. Boronic compound complexing reagents and complexes
US5623055A (en) * 1994-01-28 1997-04-22 Prolinx, Inc. Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation
US5594151A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexing reagents derived from aminosalicylic acid
US5594111A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexes for bioconjugate preparation
US5631364A (en) * 1994-03-31 1997-05-20 Axis Biochemicals Asa Labelled boronic acid derivatives
GB9415143D0 (en) * 1994-07-27 1994-09-14 Edwards Raymond Glycated haemoglobin assay
WO1996011398A1 (en) * 1994-10-07 1996-04-18 Merck & Co., Inc. Process for assessing tubulin protein polymerization
US5695949A (en) * 1995-04-07 1997-12-09 Lxn Corp. Combined assay for current glucose level and intermediate or long-term glycemic control
GB9508278D0 (en) * 1995-04-24 1995-06-14 Axis Biochemicals As Haemoglobin standards
JP3269765B2 (ja) * 1995-12-14 2002-04-02 富士写真フイルム株式会社 ヘモグロビン誘導体の免疫学的測定方法及びその方法に用いる処理試薬
US6001573A (en) * 1996-06-14 1999-12-14 Packard Bioscience B.V. Use of porphyrins as a universal label
US6075126A (en) * 1996-08-05 2000-06-13 Prolinx, Inc. Phenyldiboronic acid reagents and complexes
US6156884A (en) * 1996-08-05 2000-12-05 Prolinx, Inc. Bifunctional boronic compound complexing reagents and complexes
US6162645A (en) * 1997-03-13 2000-12-19 Abbott Laboratories Determination of % glycated hemoglobin
US6316265B1 (en) 1997-03-13 2001-11-13 Abbott Laboratories Determination of % glycated hemoglobin
DE19843094A1 (de) 1998-09-21 2000-03-23 Roche Diagnostics Gmbh Verfahren zur Bestimmung von glykiertem Hämoglobin
DE19856433C2 (de) * 1998-12-08 2001-09-13 Aventis Behring Gmbh Verfahren zum spezifischen Nachweis von glykosilierten Proteinen
RU2159442C1 (ru) * 1999-11-23 2000-11-20 Закрытое акционерное общество "Вектор-Бест" Набор реагентов для определения концентрации гемоглобина в крови
US7470420B2 (en) * 2000-12-05 2008-12-30 The Regents Of The University Of California Optical determination of glucose utilizing boronic acid adducts
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
US6653141B2 (en) 2000-12-05 2003-11-25 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing method and device
US7195923B2 (en) * 2001-01-31 2007-03-27 Scripps Laboratories, Inc. Ratiometric determination of glycated protein
GB0110053D0 (en) * 2001-04-24 2001-06-13 Axis Shield Asa Assay
US6852503B1 (en) * 2001-05-30 2005-02-08 Pierce Biotechnology, Inc. Compositions and methods for utilizing mixed substrate solutions of luminols and dioxetanes
US7670853B2 (en) * 2002-11-05 2010-03-02 Abbott Diabetes Care Inc. Assay device, system and method
RU2234703C1 (ru) * 2002-12-18 2004-08-20 Мищенко Борис Петрович Способ количественного определения гликогемоглобина
US7390670B2 (en) * 2003-02-20 2008-06-24 Lumigen, Inc. Signalling compounds and methods for detecting hydrogen peroxide
CA2514010A1 (en) * 2004-08-03 2006-02-03 Axis-Shield Diagnostics Limited Assay
EP1877801A4 (en) * 2005-04-25 2009-03-18 Protemix Corp Ltd ANALYSIS AND THERAPY OF COPPER REGULATION
GB2436681B (en) * 2006-03-31 2010-10-13 Quotient Diagnostics Ltd Fluorescent assay
US20100012049A1 (en) * 2006-04-12 2010-01-21 Jms Co., Ltd Cavitation heating system and method
US8338183B2 (en) * 2006-07-29 2012-12-25 I-Sens, Inc. Electrochemical determination system of glycated proteins
RU2378315C1 (ru) * 2008-04-17 2010-01-10 Закрытое акционерное общество "ДиаМорф" Полифункциональная хемилюминесцентная композиция
KR101005559B1 (ko) 2008-07-15 2011-01-05 주식회사 아이센스 바이오센서를 이용한 단백질 측정 장치
AU2009305121A1 (en) * 2008-10-14 2010-04-22 Piramal Healthcare Limited Non-enzymatic electrochemical method for simultaneous determination of total hemoglobin and glycated hemoglobin
EP2444803A4 (en) 2009-06-19 2012-11-14 Infopia Co Ltd METHOD FOR MEASURING GLYCED HEMOGLOBIN
EP2805164B1 (en) * 2012-01-16 2017-11-08 Koninklijke Philips N.V. Determining a presence of target molecules in a body fluid comprising cells
GB201215571D0 (en) 2012-08-31 2012-10-17 Axis Shield Asa Assay method
KR20140032221A (ko) * 2012-09-06 2014-03-14 삼성전자주식회사 시료 중의 당화 단백질을 확인하는 방법 및 그를 위한 장치
RU2612092C1 (ru) * 2015-12-08 2017-03-02 Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения Российской Федерации (ФГБУ "РКНПК" Минздрава России) Способ диагностики сахарного диабета по уровню метилглиоксаль-модифицированных липопротеидов низкой плотности с использованием моноклональных антител
CN107153121B (zh) * 2017-04-12 2019-03-08 深圳市东邦生物医疗技术有限公司 糖化血红蛋白、血红蛋白检测试剂盒及其检测方法
CN115825293B (zh) * 2023-02-21 2023-10-13 艾康生物技术(杭州)有限公司 一种用于糖化血红蛋白测试的试剂盒
CN119804843A (zh) * 2024-12-31 2025-04-11 深圳市新产业生物医学工程股份有限公司 全血样本中待测物的免疫学检测方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4269605A (en) * 1978-06-28 1981-05-26 Amicon Corporation Method and kit for separation of glycoproteins
US4268270A (en) * 1979-04-30 1981-05-19 Children's Hospital Medical Center Glycosylated hemoglobin measurement
FR2464475A1 (fr) * 1979-08-30 1981-03-06 Amicon Corp Procede et produit pour la separation des glycoproteines et leur application notamment a la determination de l'hemoglobine glycosylee
JPS5640694A (en) * 1979-09-06 1981-04-16 Amicon Corp Method of separating glycoprotein and chemical agent therefor
US4371374A (en) * 1980-11-17 1983-02-01 The Rockefeller University Monitoring metabolic control in diabetic patients by measuring glycosylated amino acids and peptides in urine
US4407961A (en) * 1981-03-16 1983-10-04 Sanders James L Ion-exchange system and method for isolation and determination of glycosylated hemoglobin in human blood
US4659817A (en) * 1981-05-01 1987-04-21 The Children's Medical Center Corporation Reporter compounds containing boron
GB8504521D0 (en) * 1985-02-21 1985-03-27 Genetics Int Inc Electrochemical assay
US4861728A (en) * 1987-07-24 1989-08-29 Becton, Dickinson And Company Immunoassay of glycosylated hemoglobin using a labeled boron reagent
US5137833A (en) * 1989-09-21 1992-08-11 Russell Anthony P Method for detecting polyhydroxyl compounds

Also Published As

Publication number Publication date
KR920701824A (ko) 1992-08-12
HU215181B (hu) 1998-10-28
CA2055430C (en) 1999-08-31
NO302784B1 (no) 1998-04-20
US5242842A (en) 1993-09-07
WO1990013818A1 (en) 1990-11-15
EP0471774B1 (en) 1995-01-25
HU904320D0 (en) 1992-02-28
DK0471774T3 (da) 1995-03-20
ATE117806T1 (de) 1995-02-15
HUT66835A (en) 1995-01-30
DE69016423T2 (de) 1995-06-14
NO890029D0 (no) 1989-01-04
FI100437B (fi) 1997-11-28
NO901643D0 (no) 1990-04-11
NO914372D0 (no) 1991-11-08
NO914372L (no) 1992-01-09
KR960010697B1 (ko) 1996-08-07
RU2111494C1 (ru) 1998-05-20
CA2055430A1 (en) 1990-11-12
EP0471774A1 (en) 1992-02-26
NO891929D0 (no) 1989-05-11
BR9007357A (pt) 1992-04-21
JPH04506703A (ja) 1992-11-19
FI915284A0 (fi) 1991-11-08
DE69016423D1 (de) 1995-03-09
JPH0812196B2 (ja) 1996-02-07
AU642879B2 (en) 1993-11-04
AU5667090A (en) 1990-11-29

Similar Documents

Publication Publication Date Title
ES2067029T3 (es) Ensayo de hemoglobina glicosilada.
ES2430941T3 (es) Procedimiento no proteolítico de determinación de analitos en estructuras queratinizadas
DK0557350T3 (da) Assay for glycerede blodproteiner
ES2047334T3 (es) Metodo de analisis optico.
LV10538A (lv) Imunologiski saistamas vielas noteiksanas panemiens biologiska skidruma un diagnostikas lidzeklis
SE7906148L (sv) Forfarande for framstellning av en biologisk komposition for anvendning sasom referenskontroll vid diagnostiska tester
EP0752426A2 (de) Synthetische Kalibratoren für den Einsatz in Immunoassays, bestehend aus Analyten oder Teilsequenzen davon, die an inerte Trägermoleküle konjugiert sind
ATE210825T1 (de) Küvette für eine analysevorrichtung, verfahren und diagnostischer testsatz zur feststellung von analyten in vollblutproben
SE8701905D0 (sv) A method and a kit for the diagnosis of iga nephropathy
EP0077515B1 (de) Verfahren und Reagenz zur Bestimmung von glykosiliertem Hämoglobin
ES2185104T3 (es) Eliminacionde las interferencias en procedimientos de diagnostico mediante peptidos de d-aminoacidos.
EP1043587A4 (en) METHOD FOR EXAMINING KIDNEY DISEASES
DK0878715T3 (da) Cyanidholdig hæmoglobinreagenssammensætning og fremgangsmåder, som giver acceptabel præcision, nøjagtighed og frihed for interferens fra hvide blodlegemer på automatiserede hæmatologi-analysatorer
ES2036189T3 (es) Un metodo para efectuar un inmunoensayo de diagnostico.
RU97112319A (ru) Способ определения стадии патологического процесса в тестах оценки функциональной активности лимфоцитов
SU1175442A1 (ru) Способ диагностики гипоксии мозга у новорожденных
TEST gsDA FoREST SERVICE RESEARCH NOTE NE. 136
RU97101930A (ru) Способ оценки индивидуальной чувствительности больных к гемоконтактным препаратам для гемосорбционных процедур
BROWN Assurance of software quality(Final Report)

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 471774

Country of ref document: ES