ES2067634T3 - Composicion farmaceutica con propiedad mejorada de disolucion. - Google Patents

Composicion farmaceutica con propiedad mejorada de disolucion.

Info

Publication number
ES2067634T3
ES2067634T3 ES90122693T ES90122693T ES2067634T3 ES 2067634 T3 ES2067634 T3 ES 2067634T3 ES 90122693 T ES90122693 T ES 90122693T ES 90122693 T ES90122693 T ES 90122693T ES 2067634 T3 ES2067634 T3 ES 2067634T3
Authority
ES
Spain
Prior art keywords
improved dissolution
dissolution property
pharmaceutical composition
pharmaceutical compositions
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90122693T
Other languages
English (en)
Inventor
Kenji Ogawa
Toshiyuki Shibata
Hirofumi Samemoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Yoshitomi Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical Industries Ltd filed Critical Yoshitomi Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of ES2067634T3 publication Critical patent/ES2067634T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSICIONES FARMACEUTICAS CON PROPIEDAD DE DISOLUCION PERFECCIONADA, OBTENIDAS MEZCLANDO Y PULVERIZANDO COMPUESTOS BENZOTIEPINO[5,4-C]PIRIDAZINO REPRESENTADOS POR LA FORMULA CON DERIVADOS DE ALMIDON(ES) DE DISTINTAS PLANTAS Y/O DERIVADO(S) DE LAS MISMAS EN UNA PROPORCION DE PESO 1:4 OS PARA PREPARACIONES FARMACEUTICAS Y FORMULACIONES DE LAS MISMAS EN PREPARACIONES. LAS COMPOSICIONES FARMACEUTICAS DE LA INVENCION EXHIBEN UN EFECTO SUPERIOR DE MEJORADO DE LA DISOLUCION ACOMPAÑADO DE UN AUMENTO DE LA SOLUBILIDAD DEL COMPUESTO (I) PER SE AL SER COMPARADO CON EL QUE SE OBTIENE COMO CUANDO SE DISUELVE SOLO EL COMPUESTO.
ES90122693T 1989-05-30 1990-11-28 Composicion farmaceutica con propiedad mejorada de disolucion. Expired - Lifetime ES2067634T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1138340A JPH0818985B2 (ja) 1989-05-30 1989-05-30 溶出性の改良された製剤組成物

Publications (1)

Publication Number Publication Date
ES2067634T3 true ES2067634T3 (es) 1995-04-01

Family

ID=15219630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90122693T Expired - Lifetime ES2067634T3 (es) 1989-05-30 1990-11-28 Composicion farmaceutica con propiedad mejorada de disolucion.

Country Status (5)

Country Link
EP (1) EP0487768B1 (es)
JP (1) JPH0818985B2 (es)
AT (1) ATE117545T1 (es)
DE (1) DE69016439T2 (es)
ES (1) ES2067634T3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255125A (ja) * 1992-02-29 1993-10-05 Upjohn Co:The 徐放性製剤およびその製法
EA004872B1 (ru) * 1999-08-03 2004-08-26 ЛИЛЛИ АЙКОС эЛ-эЛ-Си β-КАРБОЛИНОВЫЕ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
WO2007103453A1 (en) * 2006-03-06 2007-09-13 Teva Pharmaceutical Industries Ltd. Ezetimibe compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2038708T3 (es) * 1987-03-02 1996-07-16 Yoshitomi Pharmaceutical Metodo para producir compuestos de benzotiepino(5,4-c)piridazina.

Also Published As

Publication number Publication date
DE69016439D1 (de) 1995-03-09
EP0487768B1 (en) 1995-01-25
ATE117545T1 (de) 1995-02-15
JPH032120A (ja) 1991-01-08
JPH0818985B2 (ja) 1996-02-28
EP0487768A1 (en) 1992-06-03
DE69016439T2 (de) 1995-06-29

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