ES2068151A1 - Microespuma inyectable para esclerosis. - Google Patents

Microespuma inyectable para esclerosis.

Info

Publication number
ES2068151A1
ES2068151A1 ES09301413A ES9301413A ES2068151A1 ES 2068151 A1 ES2068151 A1 ES 2068151A1 ES 09301413 A ES09301413 A ES 09301413A ES 9301413 A ES9301413 A ES 9301413A ES 2068151 A1 ES2068151 A1 ES 2068151A1
Authority
ES
Spain
Prior art keywords
microfoam
sclerosing
sclerosing agent
injectable
sclerotherapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09301413A
Other languages
English (en)
Other versions
ES2068151B1 (es
Inventor
Garrido Juan Ramon Cabrera
Garcia-Olmedo Juan Cabrera
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8282315&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2068151(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Priority to ES09301413A priority Critical patent/ES2068151B1/es
Priority to AT94918886T priority patent/ATE179598T1/de
Priority to PCT/ES1994/000064 priority patent/WO1995000120A1/es
Priority to DE69418286T priority patent/DE69418286T2/de
Priority to EP94918886A priority patent/EP0656203B3/en
Priority to AU70012/94A priority patent/AU7001294A/en
Priority to DK94918886T priority patent/DK0656203T3/da
Priority to ES94918886T priority patent/ES2131689T7/es
Priority to US08/407,595 priority patent/US5676962A/en
Publication of ES2068151A1 publication Critical patent/ES2068151A1/es
Publication of ES2068151B1 publication Critical patent/ES2068151B1/es
Application granted granted Critical
Priority to GR990401341T priority patent/GR3030248T3/el
Priority to US10/458,806 priority patent/USRE38919E1/en
Priority to US10/941,013 priority patent/USRE40640E1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/122Foams; Dry foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/08Ethers or acetals acyclic, e.g. paraformaldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/07Microporous membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

MICROESPUMA INYECTABLE PARA ESCLEROSIS. PROCEDIMIENTO PARA LA ELABORACION DE MICROESPUMA INYECTABLE PARA USOS TERAPEUTICOS. LA ESCLEROSIS DE VARICES SE BASA EN LA INYECCION DE SUSTANCIAS LIQUIDAS DE CONOCIDA CAPACIDAD PARA SUPRIMIRLAS. LA PRESENTE INVENCION SE REFIERE A LA PREPARACION DE SUSTANCIAS ESCLEROSANTES EN FORMA DE MICROESPUMA. AL ELABORAR LA MICROESPUMA CON ESCLEROSANTES, Y SU POSTERIOR INYECCION EN LA VENA A TRATAR, ESTA MICROESPUMA DESPLAZA LA SANGRE QUE CONTIENE LA VENA Y GARANTIZA EL CONTACTO DEL ESCLEROSANTE CON EL ENDOTELIO DEL VASO, A CONCENTRACION CONOCIDA Y DURANTE UN TIEMPO CONTROLABLE.
ES09301413A 1993-06-23 1993-06-23 Microespuma inyectable para esclerosis. Expired - Lifetime ES2068151B1 (es)

Priority Applications (12)

Application Number Priority Date Filing Date Title
ES09301413A ES2068151B1 (es) 1993-06-23 1993-06-23 Microespuma inyectable para esclerosis.
DK94918886T DK0656203T3 (da) 1993-06-23 1994-06-21 Injicerbart mikroskum indeholdende et scleroserende middel
PCT/ES1994/000064 WO1995000120A1 (es) 1993-06-23 1994-06-21 Microespuma inyectable conteniendo un agente esclerosante
DE69418286T DE69418286T2 (de) 1993-06-23 1994-06-21 Injizierbarer Mikroschaum, der ein Verödungsmittel enthält
EP94918886A EP0656203B3 (en) 1993-06-23 1994-06-21 Injectable microfoam containing a sclerosing agent
AU70012/94A AU7001294A (en) 1993-06-23 1994-06-21 Injectable microfoam containing a sclerosing agent
AT94918886T ATE179598T1 (de) 1993-06-23 1994-06-21 Injizierbarer mikroschaum, der ein verödungsmittel enthält
ES94918886T ES2131689T7 (es) 1993-06-23 1994-06-21 Microespuma inyectable que contiene un agente esclerosante.
US08/407,595 US5676962A (en) 1993-06-23 1995-02-23 Injectable microfoam containing a sclerosing agent
GR990401341T GR3030248T3 (en) 1993-06-23 1999-05-19 Injectable microfoam containing a sclerosing agent.
US10/458,806 USRE38919E1 (en) 1993-06-23 2003-06-11 Injectable microfoam containing a sclerosing agent
US10/941,013 USRE40640E1 (en) 1993-06-23 2004-09-15 Injectable microfoam containing a sclerosing agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301413A ES2068151B1 (es) 1993-06-23 1993-06-23 Microespuma inyectable para esclerosis.

Publications (2)

Publication Number Publication Date
ES2068151A1 true ES2068151A1 (es) 1995-04-01
ES2068151B1 ES2068151B1 (es) 1995-11-16

Family

ID=8282315

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09301413A Expired - Lifetime ES2068151B1 (es) 1993-06-23 1993-06-23 Microespuma inyectable para esclerosis.
ES94918886T Active ES2131689T7 (es) 1993-06-23 1994-06-21 Microespuma inyectable que contiene un agente esclerosante.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES94918886T Active ES2131689T7 (es) 1993-06-23 1994-06-21 Microespuma inyectable que contiene un agente esclerosante.

Country Status (9)

Country Link
US (3) US5676962A (es)
EP (1) EP0656203B3 (es)
AT (1) ATE179598T1 (es)
AU (1) AU7001294A (es)
DE (1) DE69418286T2 (es)
DK (1) DK0656203T3 (es)
ES (2) ES2068151B1 (es)
GR (1) GR3030248T3 (es)
WO (1) WO1995000120A1 (es)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2216708A1 (es) * 2003-04-08 2004-10-16 Antonio Luis Cabrera Garrido "solucion esclerosante".
USRE38919E1 (en) 1993-06-23 2005-12-13 Btg International Limited Injectable microfoam containing a sclerosing agent
US7025290B2 (en) 1999-05-26 2006-04-11 Btg International Limited Generation of therapeutic microfoam
US7731986B2 (en) 2003-11-17 2010-06-08 Btg International Ltd. Therapeutic foam
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
US8703827B2 (en) 2005-05-13 2014-04-22 Btg International Ltd. Therapeutic foam

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US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US20030120256A1 (en) * 2001-07-03 2003-06-26 Syntheon, Llc Methods and apparatus for sclerosing the wall of a varicose vein
US7077836B2 (en) * 2000-07-21 2006-07-18 Vein Rx, Inc. Methods and apparatus for sclerosing the wall of a varicose vein
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ES2346955T3 (es) * 2001-08-08 2010-10-22 Btg International Limited Espuma inyectable y aplicaciones farmaceuticas novedosas de la misma.
PT1458360E (pt) 2001-12-19 2011-07-13 Novartis Ag Derivados de indole como agonistas do recetor s1p1
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GB0212047D0 (en) 2002-05-24 2002-07-03 Btg Int Ltd Generation of therapeutic microfoam
GB0300586D0 (en) * 2003-01-10 2003-02-12 Btg Int Ltd Therapeutic microfoam
US7314466B2 (en) * 2003-10-02 2008-01-01 Lary G Banning Minimally invasive vascular surgery
ES2247898B1 (es) * 2003-12-18 2006-12-01 Universidad Complutense De Madrid Utilizacion de una inyeccion previa de polidocamol en forma de microespuma para la extirpacion indolora de varices mediante laser.
ITMI20041056A1 (it) * 2004-05-26 2004-08-26 Garrido Antonio Luis Cabrera Uso in campo medico diagnostico e flebo logico di una kiscela di gas sterili e fisiologicamente accettabili
WO2006076699A1 (en) * 2005-01-14 2006-07-20 Vein Rx, Inc. Valve system for a medical device having an inflatable member
US8469924B2 (en) 2006-04-04 2013-06-25 Covidien Lp Method and apparatus for generating vascular treatment foam
US9307995B2 (en) * 2006-06-15 2016-04-12 Cook Medical Technologies Llc Methods, systems and devices for the delivery of endoluminal prostheses
US20080050436A1 (en) * 2006-08-25 2008-02-28 Chu Jack F Methods and compounds for obliteration of vessels
US20190070397A1 (en) * 2006-11-27 2019-03-07 Frank Levy Apparatus and method for producing co2 enriched medical foam
SI2125322T1 (sl) 2006-12-21 2013-07-31 Btg International Limited Naprava in postopek za izdelavo terapevtske pene
EP2187983B1 (en) * 2007-09-12 2014-04-16 Cook Incorporated Enhanced remodelable materials for occluding bodily vessels
US8157747B2 (en) 2008-02-15 2012-04-17 Lary Research & Development, Llc Single-use indicator for a surgical instrument and a surgical instrument incorporating same
BRPI1008909B8 (pt) * 2009-02-20 2021-06-22 Covidien Lp sistema para tratar uma veia
US9427233B2 (en) 2011-06-06 2016-08-30 Cook Medical Technologies, LLC Vascular occlusion devices and methods
WO2013013080A1 (en) 2011-07-20 2013-01-24 Sapheon, Inc. Enhanced ultrasound visualization of intravascular devices
US8808620B1 (en) 2012-02-22 2014-08-19 Sapheon, Inc. Sterilization process design for a medical adhesive
JP2012246306A (ja) * 2012-08-22 2012-12-13 Btg Internatl Ltd 注射可能な泡製剤および新規な医薬的適用
US20160346423A1 (en) 2014-01-07 2016-12-01 Covidien Lp Cyanoacrylate compositions including non-agglomerating radiopaque nanoparticles
EP3151951B8 (en) 2014-06-03 2020-08-05 Vascular Barcelona Devices, S.L. Methods, devices, systems and kits for preparing compositions for care and repair of varicose veins
EP2962681A1 (en) 2014-07-03 2016-01-06 Swiss VX Venentherapie und Forschung GmbH Devices and methods for injectable vascular sclerofoams using a carrier made of human blood and uses thereof
US20160045416A1 (en) * 2014-08-14 2016-02-18 John Daniel Dobak Ethanolamine oleate formulations for treatment of adipose tissue
US9687455B2 (en) 2014-08-14 2017-06-27 John Daniel Dobak Sodium tetradecyl sulfate formulations for treatment of adipose tissue
US9351945B1 (en) 2015-02-27 2016-05-31 John Daniel Dobak, III Reduction of adipose tissue
GB201611778D0 (en) 2016-07-06 2016-08-17 Provensis Ltd Method and device for producing foam
GB201612925D0 (en) * 2016-07-26 2016-09-07 Provensis Ltd Method and device for generating injectable foam
WO2019178579A1 (en) 2018-03-16 2019-09-19 Boston Scientific Scimed, Inc. Devices for vein closure
IT201800006109A1 (it) 2018-06-07 2019-12-07 Polidocanolo per uso come immunomodulatore
AU2023371657A1 (en) 2022-11-04 2025-05-15 Solvein Inc. Catheters and related methods for aspiration and controlled delivery of closure agents
US11911581B1 (en) 2022-11-04 2024-02-27 Controlled Delivery Systems, Inc. Catheters and related methods for the aspiration controlled delivery of closure agents
WO2026039577A1 (en) 2024-08-13 2026-02-19 Solvein, Inc. Device of vein treatment using coiled abrasion elements

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WO1992005806A1 (en) * 1990-10-05 1992-04-16 Sintetica S.A. Method for the preparation of stable suspensions of hollow gas-filled microspheres suitable for ultrasonic echography

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE38919E1 (en) 1993-06-23 2005-12-13 Btg International Limited Injectable microfoam containing a sclerosing agent
US7025290B2 (en) 1999-05-26 2006-04-11 Btg International Limited Generation of therapeutic microfoam
US7357336B2 (en) 1999-05-26 2008-04-15 Btg International Limited Generation of therapeutic microfoam
US7604185B2 (en) 1999-05-26 2009-10-20 Btg International Ltd. Generation of therapeutic microfoam
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
ES2216708A1 (es) * 2003-04-08 2004-10-16 Antonio Luis Cabrera Garrido "solucion esclerosante".
WO2004089358A1 (es) * 2003-04-08 2004-10-21 Antonio Luis Cabrera Garrido Solución esclerosante
US7731986B2 (en) 2003-11-17 2010-06-08 Btg International Ltd. Therapeutic foam
US7763269B2 (en) 2003-11-17 2010-07-27 Btg International Ltd. Therapeutic foam
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US8323677B2 (en) 2003-11-17 2012-12-04 Btg International Ltd. Therapeutic foam
US8703827B2 (en) 2005-05-13 2014-04-22 Btg International Ltd. Therapeutic foam

Also Published As

Publication number Publication date
USRE40640E1 (en) 2009-02-17
EP0656203B3 (en) 2011-01-26
WO1995000120A1 (es) 1995-01-05
US5676962A (en) 1997-10-14
AU7001294A (en) 1995-01-17
ES2131689T3 (es) 1999-08-01
ES2131689T7 (es) 2012-03-16
DK0656203T3 (da) 1999-11-01
ES2068151B1 (es) 1995-11-16
GR3030248T3 (en) 1999-08-31
EP0656203A1 (en) 1995-06-07
EP0656203B1 (en) 1999-05-06
DE69418286T2 (de) 1999-10-14
DE69418286D1 (de) 1999-06-10
ATE179598T1 (de) 1999-05-15
USRE38919E1 (en) 2005-12-13

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