ES2069545T3 - Ensayo y aparato que utiliza una membrana de flujo lateral y no absorbente. - Google Patents
Ensayo y aparato que utiliza una membrana de flujo lateral y no absorbente.Info
- Publication number
- ES2069545T3 ES2069545T3 ES88304988T ES88304988T ES2069545T3 ES 2069545 T3 ES2069545 T3 ES 2069545T3 ES 88304988 T ES88304988 T ES 88304988T ES 88304988 T ES88304988 T ES 88304988T ES 2069545 T3 ES2069545 T3 ES 2069545T3
- Authority
- ES
- Spain
- Prior art keywords
- complex
- lateral flow
- test
- flow membrane
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012528 membrane Substances 0.000 title abstract 2
- 239000002250 absorbent Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
SE PRESENTA UN METODO Y UN APARATO PARA REALIZAR ENSAYOS DE PAR DE UNION ESPECIFICO, TALES COMO INMUNOENSAYOS. UNA MEMBRANA POROSA DE FLUJO LATERAL NO POROSO SE USA COMO SUBSTRATO DE ENSAYO; UN MIEMBRO DEL PAR DE UNION SE FIJA EN UNA ZONA INDICADORA DEFINIDA EN EL SUBSTRATO. LA MUESTRA SE APLICA EN UNA POSICION DISTANTE DE LA ZONA INDICADORA Y QUE PERMITE EL FLUJO LATERAL A TRAVES DE LA ZONA; CUALQUIER COMPONENTE EN LA MUESTRA SE CONVIERTE EN COMPLEJO MEDIANTE EL MIEMBRO DE UNION ESPECIFICO FIJADO, Y SE DETECTA. SE PRESENTA UN NUEVO METODO DE DETECCION QUE EMPLEA LA CAPTACION DE PARTICULAS OBSERVABLES EN EL COMPLEJO. LA SANGRE ES UNA MUESTRA PARTICULARMENTE ADECUADA PUESTO QUE LAS CELULAS SANGUINEAS PUEDEN USARSE COMO PARTICULAS OBSERVABLES PARA LA DETECCION DEL COMPLEJO.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5727187A | 1987-06-01 | 1987-06-01 | |
| US5727387A | 1987-06-01 | 1987-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2069545T3 true ES2069545T3 (es) | 1995-05-16 |
Family
ID=26736266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88304988T Expired - Lifetime ES2069545T3 (es) | 1987-06-01 | 1988-06-01 | Ensayo y aparato que utiliza una membrana de flujo lateral y no absorbente. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0296724B1 (es) |
| JP (1) | JPS6459069A (es) |
| AT (1) | ATE117436T1 (es) |
| CA (1) | CA1313616C (es) |
| DE (1) | DE3852786T2 (es) |
| ES (1) | ES2069545T3 (es) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079142A (en) * | 1987-01-23 | 1992-01-07 | Synbiotics Corporation | Orthogonal flow immunoassays and devices |
| US4956302A (en) | 1987-09-11 | 1990-09-11 | Abbott Laboratories | Lateral flow chromatographic binding assay device |
| US5252496A (en) | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
| KR910014706A (ko) * | 1990-01-10 | 1991-08-31 | 원본미기재 | 세척이 필요없는 개량된 이뮤노어세이(immunoassay)장치 |
| IE75720B1 (en) * | 1990-10-08 | 1997-09-24 | Akzo Nv | Device for performing a rapid single manual assay |
| CA2027434C (en) * | 1990-10-12 | 1999-01-05 | George Jackowski | Diagnostic kit for diagnosing and distinguishing chest pain in early onset thereof |
| WO1992012428A1 (en) * | 1991-01-11 | 1992-07-23 | Quidel Corporation | A one-step lateral flow nonbibulous assay |
| AU1879392A (en) * | 1991-04-17 | 1992-11-17 | Medix Biotech, Inc. | Colorfast reference device for immunoassays |
| US6168956B1 (en) | 1991-05-29 | 2001-01-02 | Beckman Coulter, Inc. | Multiple component chromatographic assay device |
| US5869345A (en) | 1991-05-29 | 1999-02-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing conductive barrier |
| US5998220A (en) | 1991-05-29 | 1999-12-07 | Beckman Coulter, Inc. | Opposable-element assay devices, kits, and methods employing them |
| US5468648A (en) | 1991-05-29 | 1995-11-21 | Smithkline Diagnostics, Inc. | Interrupted-flow assay device |
| US5877028A (en) | 1991-05-29 | 1999-03-02 | Smithkline Diagnostics, Inc. | Immunochromatographic assay device |
| US5607863A (en) | 1991-05-29 | 1997-03-04 | Smithkline Diagnostics, Inc. | Barrier-controlled assay device |
| WO1994002850A1 (en) * | 1992-07-21 | 1994-02-03 | Medix Biotech, Inc. | Transparent assay test devices and methods |
| AU4427493A (en) * | 1992-08-03 | 1994-02-10 | Becton Dickinson & Company | Solid phase assay |
| US5424193A (en) * | 1993-02-25 | 1995-06-13 | Quidel Corporation | Assays employing dyed microorganism labels |
| JP3230561B2 (ja) * | 1995-05-09 | 2001-11-19 | シスメックス株式会社 | 攪拌装置 |
| US5874216A (en) | 1996-02-23 | 1999-02-23 | Ensys Environmental Products, Inc. | Indirect label assay device for detecting small molecules and method of use thereof |
| US5879951A (en) | 1997-01-29 | 1999-03-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing unidirectional flow |
| AU6277498A (en) * | 1997-02-15 | 1998-09-08 | Beth Israel Deaconess Medical Center | Multiple-site antibody capture immunoassays and kits |
| US6103536A (en) | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
| US5939252A (en) | 1997-05-09 | 1999-08-17 | Lennon; Donald J. | Detachable-element assay device |
| US6306642B1 (en) * | 1997-11-24 | 2001-10-23 | Quidel Corporation | Enzyme substrate delivery and product registration in one step enzyme immunoassays |
| US6372514B1 (en) * | 1998-09-18 | 2002-04-16 | Syntron Bioresearch, Inc. | Even fluid front for liquid sample on test strip device |
| US6180417B1 (en) * | 1999-04-22 | 2001-01-30 | Bayer Corporation | Immunochromatographic assay |
| US6699722B2 (en) | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
| US7041787B2 (en) | 2000-12-29 | 2006-05-09 | Kimberly-Clark Worldwide, Inc. | Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases |
| US6600057B2 (en) | 2000-12-29 | 2003-07-29 | Kimberly-Clark Worldwide, Inc. | Matrix metalloproteinase inhibitors |
| DE10330982A1 (de) * | 2003-07-09 | 2005-02-17 | Prisma Diagnostika Gmbh | Vorrichtung und Verfahren zur simultanen Bestimmung von Blutgruppenantigenen |
| NL1027737C2 (nl) * | 2004-12-14 | 2006-06-16 | Teststrip B V | Chromatografische analyse-inrichting en test kit. |
| US7879623B2 (en) * | 2006-03-31 | 2011-02-01 | Guirguis Raouf A | Integrated device for analyte, testing, confirmation, and donor identity verification |
| US7569396B1 (en) | 2006-09-08 | 2009-08-04 | Purplecow Llc | Caffeine detection using internally referenced competitive assays |
| US7919331B2 (en) | 2006-12-21 | 2011-04-05 | Silver Lake Research Corporation | Chromatographic test strips for one or more analytes |
| US20090305231A1 (en) * | 2008-04-09 | 2009-12-10 | Becton, Dickinson And Company | Sensitive Immunoassays Using Coated Nanoparticles |
| US8476008B2 (en) | 2008-07-23 | 2013-07-02 | Diabetomics, Llc | Methods for detecting pre-diabetes and diabetes |
| JP4851499B2 (ja) * | 2008-07-31 | 2012-01-11 | グローブライド株式会社 | イカツノ仕掛け及びイカ釣り用仕掛け |
| WO2010132447A2 (en) | 2009-05-11 | 2010-11-18 | Diabetomics, Llc | Methods for detecting pre-diabetes and diabetes using differential protein glycosylation |
| WO2013040142A2 (en) | 2011-09-16 | 2013-03-21 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
| EP4012714A1 (en) | 2010-03-23 | 2022-06-15 | Iogenetics, LLC. | Bioinformatic processes for determination of peptide binding |
| CN106620692B (zh) | 2010-04-09 | 2021-04-09 | 重症监护诊断股份有限公司 | 可溶性人st-2抗体和分析法 |
| EP2576806B1 (en) | 2010-05-26 | 2017-03-08 | The Board of Trustees of the University of Illionis | Personal glucose meters for detection and quantification of a broad range of analytes |
| EP2812704A4 (en) | 2012-02-07 | 2016-03-23 | Intuitive Biosciences Inc | MYCOBACTERIUM STUBERCULOSIS-SPECIFIC PEPTIDES FOR DETECTING INFECTION OR IMMUNIZATION OF NON-MUSCLE PRIMATES |
| CN104937106A (zh) | 2012-11-21 | 2015-09-23 | 奥斯陆大学医院 | 用于监测生物流体的系统和方法 |
| JP6361037B2 (ja) * | 2013-01-29 | 2018-07-25 | 国立大学法人三重大学 | イムノクロマト法で血漿タンパクを測定する方法 |
| US9052314B2 (en) | 2013-03-14 | 2015-06-09 | Silver Lake Research Corporation | Biomarkers for detecting the presence of bacteria |
| FR3012982B1 (fr) * | 2013-11-08 | 2015-12-25 | Espci Innov | Procede de stockage et de concentration d'un compose volatil |
| WO2016172660A1 (en) | 2015-04-23 | 2016-10-27 | Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno | Fungal detection using mannan epitope |
| WO2017077392A1 (en) | 2015-11-06 | 2017-05-11 | Oslo Universitetssykehus Hf | Methods and devices for detecting methanol poisoning using formate oxidase |
| EP3387154A4 (en) | 2015-12-09 | 2019-05-15 | Intuitive Biosciences, Inc. | AUTOMATED SILVER FINISHING SYSTEM |
| WO2017180047A1 (en) * | 2016-04-12 | 2017-10-19 | Meje Ab | Membrane-based analytical device for bodily fluids |
| US20190120838A1 (en) | 2016-04-13 | 2019-04-25 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone |
| WO2018203145A1 (en) | 2017-05-03 | 2018-11-08 | Oslo Universitetssykehus Hf | Systems and methods for monitoring biological fluids |
| US11300576B2 (en) | 2019-01-29 | 2022-04-12 | Arizona Board Of Regents On Behalf Of Arizona State University | DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples |
| EP4446007B1 (de) * | 2023-04-13 | 2025-09-10 | VELLAP Diagnostics GmbH | Chromatographisches schnelltest-set zur untersuchung einer probe hinsichtlich pathogenen, biomolekülen, biomarkern und chemischen stoffen |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE388694B (sv) * | 1975-01-27 | 1976-10-11 | Kabi Ab | Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar |
| FR2486657A1 (fr) * | 1980-07-09 | 1982-01-15 | Pasteur Institut | Procede de detection et de dosage d'une substance biologique par erythroadsorption |
| DE3269567D1 (en) * | 1981-04-29 | 1986-04-10 | Ciba Geigy Ag | New devices and kits for immunological analysis |
| US4608246A (en) * | 1983-03-10 | 1986-08-26 | Immucor, Inc. | Testing for a blood group immunological reaction |
| US4999285A (en) * | 1984-11-15 | 1991-03-12 | Syntex (U.S.A.) Inc. | Chromatographic cassette |
| DE3445816C1 (de) * | 1984-12-15 | 1986-06-12 | Behringwerke Ag, 3550 Marburg | Flaechenfoermiges diagnostisches Mittel |
| DE3585780D1 (de) * | 1984-12-24 | 1992-05-07 | Abbott Lab | Analytische vorrichtung und verfahren zu ihrer verwendung. |
| US4740468A (en) * | 1985-02-14 | 1988-04-26 | Syntex (U.S.A.) Inc. | Concentrating immunochemical test device and method |
| IL78854A (en) * | 1985-05-31 | 1991-11-21 | Murex Corp | Biological fluid diagnostic device |
| US4960691A (en) * | 1986-09-29 | 1990-10-02 | Abbott Laboratories | Chromatographic test strip for determining ligands or receptors |
| US5079142A (en) * | 1987-01-23 | 1992-01-07 | Synbiotics Corporation | Orthogonal flow immunoassays and devices |
| US4857453A (en) * | 1987-04-07 | 1989-08-15 | Syntex (U.S.A.) Inc. | Immunoassay device |
| ES2039533T3 (es) * | 1987-09-11 | 1993-10-01 | Abbott Laboratories | Metodos y dispositivos para llevar a cabo ensayos de union especifica. |
-
1988
- 1988-05-30 CA CA000568070A patent/CA1313616C/en not_active Expired - Fee Related
- 1988-06-01 EP EP88304988A patent/EP0296724B1/en not_active Expired - Lifetime
- 1988-06-01 DE DE3852786T patent/DE3852786T2/de not_active Expired - Lifetime
- 1988-06-01 AT AT88304988T patent/ATE117436T1/de not_active IP Right Cessation
- 1988-06-01 ES ES88304988T patent/ES2069545T3/es not_active Expired - Lifetime
- 1988-06-01 JP JP63136624A patent/JPS6459069A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0296724A2 (en) | 1988-12-28 |
| EP0296724B1 (en) | 1995-01-18 |
| EP0296724A3 (en) | 1990-12-12 |
| ATE117436T1 (de) | 1995-02-15 |
| DE3852786T2 (de) | 1995-08-17 |
| CA1313616C (en) | 1993-02-16 |
| JPS6459069A (en) | 1989-03-06 |
| DE3852786D1 (de) | 1995-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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