ES2069635T3 - Procedimiento y reactivo para la determinacion de antitrombina iii. - Google Patents

Procedimiento y reactivo para la determinacion de antitrombina iii.

Info

Publication number
ES2069635T3
ES2069635T3 ES90113483T ES90113483T ES2069635T3 ES 2069635 T3 ES2069635 T3 ES 2069635T3 ES 90113483 T ES90113483 T ES 90113483T ES 90113483 T ES90113483 T ES 90113483T ES 2069635 T3 ES2069635 T3 ES 2069635T3
Authority
ES
Spain
Prior art keywords
pro
iii
antitrombine
reagent
determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90113483T
Other languages
English (en)
Inventor
Andreas Dr Dessauer
Reinhard Herz
Helmut Dr Lill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2069635T3 publication Critical patent/ES2069635T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8128—Antithrombin III
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

EL INVENTO SE REFIERE A UN PROCEDIMIENTO PARA DETERMINAR ANTITROMBINA (III) EN CUERPOS FLUIDOS. DICHO PROCEDIMIENTO CONSISTE EN TRATAR EL CUERPO LIQUIDO CON TROMBNINA Y UN SUSTRATO CROMONOGENO QUE FORMA POR ACCION DE LA TROMBINA UN COLOR Y MEDIR EL COLOR OBTENIDO, Y SE CARACTERIZA PORQUE EL TRATAMIENTO SE REALIZA EN PRESENCIA DE AGENTES NO NATURALES O DE TETRAPEPTIDOS (GLY PTIDO CUYA SENSIBILIDAD COMPARADA CON EL TOS
ES90113483T 1989-07-14 1990-07-13 Procedimiento y reactivo para la determinacion de antitrombina iii. Expired - Lifetime ES2069635T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3923340A DE3923340A1 (de) 1989-07-14 1989-07-14 Verfahren und reagenz zur bestimmung von antithrombin iii

Publications (1)

Publication Number Publication Date
ES2069635T3 true ES2069635T3 (es) 1995-05-16

Family

ID=6385054

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90113483T Expired - Lifetime ES2069635T3 (es) 1989-07-14 1990-07-13 Procedimiento y reactivo para la determinacion de antitrombina iii.

Country Status (8)

Country Link
EP (1) EP0408075B1 (es)
JP (1) JPH0734759B2 (es)
AT (1) ATE119578T1 (es)
AU (1) AU622339B2 (es)
DD (1) DD298444A5 (es)
DE (2) DE3923340A1 (es)
ES (1) ES2069635T3 (es)
ZA (1) ZA905489B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU628960B2 (en) * 1989-04-07 1992-09-24 Teijin Limited Method of immunologically assaying human thrombin- antithrombin III complex, assay reagent and kit therefor
JPH078298A (ja) * 1993-06-28 1995-01-13 Nippon Shoji Kk アンチトロンビンｉｉｉ活性の測定方法および該測定用試薬キット
DE59703340D1 (de) * 1996-08-17 2001-05-17 Aventis Behring Gmbh Verfahren zur Quantifizierung von Glykosaminoglykanen in Antithrombin III-haltigen Lösungen
US6165795A (en) * 1998-06-25 2000-12-26 Cardiovascular Diagnostics, Inc. Methods for performing fibrinogen assays using dry chemical reagents containing ecarin and magnetic particles
DE102005003145B4 (de) 2005-01-21 2006-10-19 Dade Behring Marburg Gmbh Stablies, chromogenes Flüssigreagenz und dessen Verwendung in gerinnungsdiagnostischen Tests
GB0914883D0 (en) 2009-08-26 2009-09-30 Univ Belfast Compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3005540A1 (de) * 1980-02-14 1981-08-20 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagens zur bestimmung der biologischen aktivitaet von heparin im plasma
US4473639A (en) * 1982-09-15 1984-09-25 Miles Laboratories, Inc. Reagent strip test for antithrombin-III
DE3244030A1 (de) * 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DE3811647A1 (de) * 1988-04-07 1989-10-26 Behringwerke Ag Verfahren und verpackung enthaltend mittel zur kinetischen bestimmung von faktor xiii

Also Published As

Publication number Publication date
JPH0353898A (ja) 1991-03-07
ZA905489B (en) 1991-04-24
EP0408075A3 (en) 1992-02-26
AU622339B2 (en) 1992-04-02
EP0408075B1 (de) 1995-03-08
DE59008621D1 (de) 1995-04-13
JPH0734759B2 (ja) 1995-04-19
EP0408075A2 (de) 1991-01-16
AU5888590A (en) 1991-01-17
DE3923340A1 (de) 1991-01-24
ATE119578T1 (de) 1995-03-15
DD298444A5 (de) 1992-02-20

Similar Documents

Publication Publication Date Title
SE8804074D0 (sv) Sensorenhet och dess anvaendning i biosensorsystem
GR3036073T3 (en) Analytical test apparatus with on board negative and positive control.
ATE35000T1 (de) Reagenz zur bestimmung der thromboplastinzeit.
DK0649535T3 (da) Fremgangsmåde til at forbedre målepræcisionen i optisk biosensor assays med detektering af rumligt dæmpede bølger
NO164866C (no) Reagens og forsoeksinnretning til bestemmelse av tilstedevaerelsen av leukocytter, esterase og protease i en proeve.
ES2071067T3 (es) Procedimiento para la deteccion de microorganismos que implican la utilizacion de resorufina u orcirufina.
ES2063821T3 (es) Composicion de reactivo que comprende un dador de enzima.
KR960007789A (ko) 단백질 c/단백질 s시스템의 장해를 검출하기 위한 방법
SE7613463L (sv) Specifika kromogena enzymsubstrat
ES2069635T3 (es) Procedimiento y reactivo para la determinacion de antitrombina iii.
FI893789A0 (fi) Määritysmenetelmä ja materiaalisarja nesteessä olevan entsyymin määrittämiseksi
ES2097373T3 (es) Analisis de la proteina s.
ATE40718T1 (de) Verfahren zur bestimmung von fibrinmonomer in plasma.
JPS57178161A (en) Reagent for optically measuring blood coagulation reaction
DE3663684D1 (de) Determination of prokallikrein
NO823508L (no) Reagens bestemmelse av ristocetin-kofaktoren (willebrand-faktor).
AU655405B2 (en) Enzymatic method for determining analyte concentrations
NO308140B1 (no) Anvendelse av protrombinfragmenter
FR2399663A1 (fr) Composition et procede pour determiner l'activite transferasique et proteasique
ES2169211T3 (es) Ensayos de proteccion de micelas.
DE3485740D1 (de) Immunologisches testverfahren eines prokoagulierenden enzyms zum nachweis von krebs.
NZ297230A (en) Thiepane compounds for detecting HIV protease

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 408075

Country of ref document: ES