ES2069647T3 - Nuevos derivados de inosina/guanosina. - Google Patents

Nuevos derivados de inosina/guanosina.

Info

Publication number
ES2069647T3
ES2069647T3 ES90119493T ES90119493T ES2069647T3 ES 2069647 T3 ES2069647 T3 ES 2069647T3 ES 90119493 T ES90119493 T ES 90119493T ES 90119493 T ES90119493 T ES 90119493T ES 2069647 T3 ES2069647 T3 ES 2069647T3
Authority
ES
Spain
Prior art keywords
hydrogen
group
inosina
guanosina
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90119493T
Other languages
English (en)
Inventor
Esa T Jarvi
Alan J Bitonti
James R Mccarthy
Russell J Baumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2069647T3 publication Critical patent/ES2069647T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

ESTE INVENTO RELATA NUEVOS COMPONENTES DE LA FORMULA EN DONDE X1 Y X2 SON CADA UNO INDEPENDIENTEMENTE HIDROGENO O HALOGENO CON LA PREVISION DE QUE AL MENOS UNO DE X1, Y X2 SEAN HALOGENO, A1 Y A2 SON CADA UNO INDEPENDIENTEMENTE HIDROGENO, HALOGENO O HIDROXI CON LAS PREVISIONES DE QUE CUANDO A1 ES HIDROXI, A2 ES HIDROGENO, Y CUANDO A2 ES HIDROXI, A1 ES HIDROGENO, Y1 ES NITROGENO, UN GRUPO CH, UN GRUPO CCL, UN GRUPO CBR O UN GRUPO CNH2, Y2 ES NITROGENO O UN GRUPO CH, Y Z ES HIDROGENO, HALOGENO O NH2, QUE SON UTILES COMO AGENTES ANTIPROTOZOALES.
ES90119493T 1989-10-11 1990-10-11 Nuevos derivados de inosina/guanosina. Expired - Lifetime ES2069647T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41981289A 1989-10-11 1989-10-11

Publications (1)

Publication Number Publication Date
ES2069647T3 true ES2069647T3 (es) 1995-05-16

Family

ID=23663862

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90119493T Expired - Lifetime ES2069647T3 (es) 1989-10-11 1990-10-11 Nuevos derivados de inosina/guanosina.

Country Status (17)

Country Link
EP (1) EP0422638B1 (es)
JP (1) JP3053420B2 (es)
KR (1) KR0160123B1 (es)
CN (1) CN1050880A (es)
AT (1) ATE117315T1 (es)
AU (1) AU632856B2 (es)
CA (1) CA2027023C (es)
DE (1) DE69016149T2 (es)
ES (1) ES2069647T3 (es)
FI (1) FI904981A7 (es)
HU (1) HUT55027A (es)
IE (1) IE903630A1 (es)
IL (1) IL95929A0 (es)
NO (1) NO904381L (es)
NZ (1) NZ235577A (es)
PT (1) PT95556A (es)
ZA (1) ZA907994B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225906A (en) * 1987-08-26 1990-10-26 Merrell Dow Pharma Aristeromycin/adenosine derivatives and pharmaceutical compositions
US4997926A (en) * 1987-11-18 1991-03-05 Scripps Clinic And Research Foundation Deaminase-stable anti-retroviral 2-halo-2',3'-dideoxy
US4897177A (en) * 1988-03-23 1990-01-30 Exxon Chemical Patents Inc. Process for reforming a hydrocarbon fraction with a limited C9 + content
US4996308A (en) * 1988-03-25 1991-02-26 Merrell Dow Pharmaceuticals Inc. Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group

Also Published As

Publication number Publication date
EP0422638A1 (en) 1991-04-17
DE69016149T2 (de) 1995-05-18
ZA907994B (en) 1991-07-31
NO904381D0 (no) 1990-10-10
CN1050880A (zh) 1991-04-24
HU906407D0 (en) 1991-04-29
KR910007954A (ko) 1991-05-30
KR0160123B1 (ko) 1998-11-16
AU632856B2 (en) 1993-01-14
FI904981A0 (fi) 1990-10-10
IL95929A0 (en) 1991-07-18
JP3053420B2 (ja) 2000-06-19
DE69016149D1 (de) 1995-03-02
NZ235577A (en) 1993-01-27
NO904381L (no) 1991-04-12
CA2027023A1 (en) 1991-04-12
EP0422638B1 (en) 1995-01-18
AU6384290A (en) 1991-04-18
FI904981A7 (fi) 1991-04-12
ATE117315T1 (de) 1995-02-15
HUT55027A (en) 1991-04-29
JPH03133992A (ja) 1991-06-07
IE903630A1 (en) 1991-04-24
PT95556A (pt) 1991-08-14
CA2027023C (en) 2001-12-25

Similar Documents

Publication Publication Date Title
DK504089A (da) Strikkede metalstrukturer
PT776893E (pt) Compostos azaciclicos com actividade antagonista do receptor de taquiquinina; nk1 e nk2
BR9005343A (pt) Derivado de triazina,e herbicida que o contem como ingrediente ativo
ES2072096T3 (es) 4-fenilpiperidinas n-sustituidas antagonistas de opioides.
TR199801255T2 (xx) Vitronektin resept�r antagonistleri.
EP1029860A4 (en) BENZOFURANE DERIVATIVES
DE69023209D1 (de) Weichmachende und antistatische Zusammensetzungen für Textilien.
ES2194444T3 (es) Agonistas y antagonistas de 20-hete.
ES2090071T3 (es) Derivados de uracilo y su produccion y uso.
ES2038690T3 (es) Aminoacidos insaturados.
ES2120037T3 (es) 1-fenil- o 1-piridinil-benzotriazoles substituidos herbicidas.
ES2192584T3 (es) Derivado pirimidinilpirazol.
ATE198202T1 (de) Fibrinogen receptor antagonisten
TR200000738T2 (tr) Difosjenden ve/veya trifosjenden fosjen hazırlanması için yöntem ve gereç.
DK1485625T3 (da) Radioisotopgenerator omfattende én eller flere elementstøtter
AR241470A1 (es) Una composicion herbicida cuyo ingrediente activo es un n-feniltriazol-derivados de n-fenil triazol. procedimiento para la preparacion de dichos compuestos.
ES2058849T3 (es) Benzanilidas.
ES2063831T3 (es) Derivados de 4,5,6,7-tetrahidrobencimidazol y su preparacion.
AR246122A1 (es) Nuevos hidroxietil-azolil-derivados y procedimientos para su obtencion, intermediarios y composiciones fungicidas y reguladoras del crecimiento de plantas.
AR009452A1 (es) Compuestos de dihalopropeno, los agentes insecticidas/acaricidas que los contienen y los intermediarios de sintesis de dichos compuestos.
ES2051911T3 (es) Tiadiacinas, procedimiento para su produccion, y agentes insecticidas y acaricidas que comprenden las tiadiacinas.
ES2189390T3 (es) Fungicidas.
TW340788B (en) Ester compounds and household insects-controlling agents containing the same as an active ingredient
PT998205E (pt) Solucao de acido formico com reduzido efeito corrosivo
ATE475337T1 (de) Halter für wendetafeln od. dgl.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 422638

Country of ref document: ES