ES2070262T3 - Un metodo para preparar una composicion seca de factor de crecimiento i de tipo insulina. - Google Patents

Un metodo para preparar una composicion seca de factor de crecimiento i de tipo insulina.

Info

Publication number
ES2070262T3
ES2070262T3 ES90125816T ES90125816T ES2070262T3 ES 2070262 T3 ES2070262 T3 ES 2070262T3 ES 90125816 T ES90125816 T ES 90125816T ES 90125816 T ES90125816 T ES 90125816T ES 2070262 T3 ES2070262 T3 ES 2070262T3
Authority
ES
Spain
Prior art keywords
acid
growth factor
preparing
dry composition
insulin type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90125816T
Other languages
English (en)
Inventor
Shigeo Nakanishi
Iwao Yamanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2070262T3 publication Critical patent/ES2070262T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Inorganic Chemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

ES UN METODO PARA PREPARAR UNA COMPOSICION SECA QUE CONTIENE EL FACTOR I DE CRECIMIENTO SIMILAR A LA INSULINA JUNTO CON UN ACIDO FUERTE ELEGIDO ENTRE EL ACIDO HIDROCLORICO, EL ACIDO HIDROBROMICO, EL ACIDO NITRICO, EL ACIDO METANOSULFONICO, EL ACIDO SULFURICO, EL ACIDO FOSFORICO, Y EL ACIDO OXALICO.
ES90125816T 1990-01-05 1990-12-29 Un metodo para preparar una composicion seca de factor de crecimiento i de tipo insulina. Expired - Lifetime ES2070262T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP88690 1990-01-05
JP16236290 1990-06-20

Publications (1)

Publication Number Publication Date
ES2070262T3 true ES2070262T3 (es) 1995-06-01

Family

ID=26334000

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90125816T Expired - Lifetime ES2070262T3 (es) 1990-01-05 1990-12-29 Un metodo para preparar una composicion seca de factor de crecimiento i de tipo insulina.

Country Status (10)

Country Link
US (1) US5210074A (es)
EP (1) EP0440989B1 (es)
JP (1) JPH0818999B2 (es)
AT (1) ATE120763T1 (es)
CA (1) CA2033535A1 (es)
DE (1) DE69018438T2 (es)
DK (1) DK0440989T3 (es)
ES (1) ES2070262T3 (es)
GR (1) GR3015712T3 (es)
IL (1) IL96839A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW267102B (es) * 1992-03-13 1996-01-01 Ciba Geigy
US5783556A (en) * 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
JP2001522813A (ja) * 1997-11-07 2001-11-20 カイロン コーポレイション 新規のｉｇｆ−ｉ組成物およびその使用
US7067485B2 (en) 1997-11-07 2006-06-27 Chiron Corporation IGF-I composition and its use
US6284282B1 (en) 1998-04-29 2001-09-04 Genentech, Inc. Method of spray freeze drying proteins for pharmaceutical administration
AU3764199A (en) * 1998-04-29 1999-11-16 Genentech Inc. Spray dried formulations of igf-i
ES2208305T3 (es) 1999-04-08 2004-06-16 Genentech, Inc. Composicion basada en polipeptidos de carga opuesta..
CA2637569C (en) * 2006-01-18 2013-01-08 Yuhua Li Pharmaceutical compositions with enhanced stability
US20180256717A1 (en) * 2014-12-23 2018-09-13 Drug Discovery Laboratory As Protein compositions and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139611A (en) * 1975-12-24 1979-02-13 Helmut Mittenzweig Organic peptide containing substance recovered from blood having insulin-like activity
US4371523A (en) * 1980-12-29 1983-02-01 The Regents Of The University Of California Reducing the aggregation of insulin in solution
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4985404A (en) * 1984-10-04 1991-01-15 Monsanto Company Prolonged release of biologically active polypeptides
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor

Also Published As

Publication number Publication date
JPH0818999B2 (ja) 1996-02-28
ATE120763T1 (de) 1995-04-15
DE69018438T2 (de) 1995-08-24
EP0440989A1 (en) 1991-08-14
DE69018438D1 (de) 1995-05-11
JPH04208228A (ja) 1992-07-29
EP0440989B1 (en) 1995-04-05
IL96839A (en) 1995-03-30
GR3015712T3 (en) 1995-07-31
CA2033535A1 (en) 1991-07-06
US5210074A (en) 1993-05-11
DK0440989T3 (da) 1995-05-01
IL96839A0 (en) 1991-09-16

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