ES2070842T3 - Derivados fluorados del acido araquidonico. - Google Patents

Derivados fluorados del acido araquidonico.

Info

Publication number
ES2070842T3
ES2070842T3 ES88118314T ES88118314T ES2070842T3 ES 2070842 T3 ES2070842 T3 ES 2070842T3 ES 88118314 T ES88118314 T ES 88118314T ES 88118314 T ES88118314 T ES 88118314T ES 2070842 T3 ES2070842 T3 ES 2070842T3
Authority
ES
Spain
Prior art keywords
fluorated
derivatives
araquidonic acid
araquidonic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88118314T
Other languages
English (en)
Inventor
Jean Bernard Ducep
Jean-Francois Nave
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2070842T3 publication Critical patent/ES2070842T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5428—Acyclic unsaturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DERIVADOS DEL ACIDO ARAQUIDONICO FLUORADOS SON INHIBIDORES DE 5 - LIPOSIGENOSA, LOS CUALES TIENEN ACTIVIDAD FARMACOLOGICA UTIL PARA EL TRATAMIENTO COMO AGENTES ANTIALERGICOS Y AQNTIINFLAMATORIOS Y SON UTILES PARA EL TRATAMIENTO DE ASMA ANAGILASIS, ALERGIA, ARTRITIS REUMATOIDE Y PSODIASIS
ES88118314T 1987-11-04 1988-11-03 Derivados fluorados del acido araquidonico. Expired - Lifetime ES2070842T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11716587A 1987-11-04 1987-11-04

Publications (1)

Publication Number Publication Date
ES2070842T3 true ES2070842T3 (es) 1995-06-16

Family

ID=22371305

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88118314T Expired - Lifetime ES2070842T3 (es) 1987-11-04 1988-11-03 Derivados fluorados del acido araquidonico.

Country Status (17)

Country Link
EP (1) EP0315166B1 (es)
JP (1) JP2799865B2 (es)
KR (1) KR0126134B1 (es)
CN (1) CN1032935A (es)
AT (1) ATE118757T1 (es)
AU (1) AU609535B2 (es)
CA (1) CA1333397C (es)
DE (1) DE3853126T2 (es)
DK (1) DK614688A (es)
ES (1) ES2070842T3 (es)
FI (1) FI885053A7 (es)
HU (1) HU199412B (es)
IL (1) IL88270A0 (es)
NO (1) NO170800C (es)
NZ (1) NZ226815A (es)
PT (1) PT88933B (es)
ZA (1) ZA888155B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0396841B1 (en) * 1989-05-02 1994-02-02 Merrell Dow Pharmaceuticals Inc. Fluorinated arachidonic acid derivatives
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
CN101928229A (zh) * 2010-07-01 2010-12-29 黄冈华阳药业有限公司 生产左乙拉西坦的中间体l-2-氨基丁酰胺盐酸盐的工艺方法
CA2776178A1 (en) * 2012-04-05 2013-10-05 Hydro-Quebec Ionic compounds
JP6853982B2 (ja) * 2015-08-27 2021-04-07 ユニバーシティ アンジェ トコトリエノール誘導体、医薬組成物および５−リポキシゲナーゼ関連疾患における使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61271246A (ja) * 1985-05-25 1986-12-01 Asahi Glass Co Ltd ５−フレオロアラキドン酸誘導体およびその製造法
JPS61271234A (ja) * 1985-05-25 1986-12-01 Asahi Glass Co Ltd ビニルフルオリド誘導体およびその製造法

Also Published As

Publication number Publication date
DE3853126D1 (de) 1995-03-30
ZA888155B (en) 1989-07-26
IL88270A0 (en) 1989-06-30
HUT48194A (en) 1989-05-29
PT88933A (pt) 1988-12-01
KR0126134B1 (ko) 1997-12-26
NO170800C (no) 1992-12-09
NZ226815A (en) 1991-06-25
EP0315166B1 (en) 1995-02-22
PT88933B (pt) 1993-01-29
HU199412B (en) 1990-02-28
DK614688A (da) 1989-05-05
EP0315166A3 (en) 1991-03-27
NO884905D0 (no) 1988-11-03
AU609535B2 (en) 1991-05-02
DE3853126T2 (de) 1995-06-14
FI885053A7 (fi) 1989-05-05
NO170800B (no) 1992-08-31
EP0315166A2 (en) 1989-05-10
CN1032935A (zh) 1989-05-17
NO884905L (no) 1989-05-05
JP2799865B2 (ja) 1998-09-21
FI885053A0 (fi) 1988-11-02
ATE118757T1 (de) 1995-03-15
JPH01151535A (ja) 1989-06-14
KR890008073A (ko) 1989-07-08
DK614688D0 (da) 1988-11-03
CA1333397C (en) 1994-12-06
AU2463688A (en) 1989-05-04

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