ES2071889T5 - Medicamento oral y material envolvente, que contiene un polisacarido que se descompone en el colon. - Google Patents

Medicamento oral y material envolvente, que contiene un polisacarido que se descompone en el colon.

Info

Publication number
ES2071889T5
ES2071889T5 ES91118734T ES91118734T ES2071889T5 ES 2071889 T5 ES2071889 T5 ES 2071889T5 ES 91118734 T ES91118734 T ES 91118734T ES 91118734 T ES91118734 T ES 91118734T ES 2071889 T5 ES2071889 T5 ES 2071889T5
Authority
ES
Spain
Prior art keywords
colon
polysaccharide
decomposes
medicinal product
envelope material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91118734T
Other languages
English (en)
Other versions
ES2071889T3 (es
Inventor
Klaus Dr Lehmann
Dieter Dreher
Pascali Giuseppe De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH Darmstadt
Original Assignee
Roehm GmbH Darmstadt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6859318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2071889(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roehm GmbH Darmstadt filed Critical Roehm GmbH Darmstadt
Application granted granted Critical
Publication of ES2071889T3 publication Critical patent/ES2071889T3/es
Publication of ES2071889T5 publication Critical patent/ES2071889T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE PRESENTAN MEDIOS DE RECUBRIMIENTO QUE CONTIENEN UNA FASE LIQUIDA, UN POLISACARIDO DESINTEGRABLE EN EL COLON, COMO PEPITA DE ALGARROBA O GUAR GUM, ASI COMO UN MATERIAL POLIMERO QUE FORMA UNA PELICULA, PREFERENTEMENTE CON GRUPOS HIDROFILOS. CON ESTE MEDIO DE RECUBRIMIENTO SE OBTIENE UN REVESTIMIENTO DE CAPAS EN MEDICAMENTOS ORALES DE ALTA RESISTENCIA MECANICA, QUE SE DESINTEGRA EN EL COLON BAJO LA ACCION DE ENCIMAS GLICOSIDAS.
ES91118734T 1990-11-14 1991-11-04 Medicamento oral y material envolvente, que contiene un polisacarido que se descompone en el colon. Expired - Lifetime ES2071889T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE9015551U DE9015551U1 (de) 1990-11-14 1990-11-14 Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccarid

Publications (2)

Publication Number Publication Date
ES2071889T3 ES2071889T3 (es) 1995-07-01
ES2071889T5 true ES2071889T5 (es) 1999-07-01

Family

ID=6859318

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91118734T Expired - Lifetime ES2071889T5 (es) 1990-11-14 1991-11-04 Medicamento oral y material envolvente, que contiene un polisacarido que se descompone en el colon.

Country Status (5)

Country Link
EP (1) EP0485840B2 (es)
AT (1) ATE119389T1 (es)
DE (2) DE9015551U1 (es)
DK (1) DK0485840T4 (es)
ES (1) ES2071889T5 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4236025A1 (de) * 1992-10-24 1994-04-28 Merck Patent Gmbh Orale Arzneiformen
EP0670717B1 (en) * 1992-11-30 1998-11-25 Pfizer Inc. Supported liquid membrane delivery devices
TW401300B (en) * 1992-12-25 2000-08-11 Senju Pharma Co Antiallergic composition for ophthalmic or nasal use
US5843479A (en) * 1993-02-26 1998-12-01 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
US5656290A (en) * 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
DE4332394A1 (de) * 1993-09-23 1995-03-30 Falk Pharma Gmbh Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung
US5849327A (en) * 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
US5656294A (en) * 1995-06-07 1997-08-12 Cibus Pharmaceutical, Inc. Colonic delivery of drugs
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
WO1997027843A2 (en) * 1996-01-30 1997-08-07 Advanced Polymer Systems, Inc. Targeted delivery of drugs to the lower gastrointestinal tract
KR100219918B1 (ko) * 1997-07-03 1999-09-01 김윤 대장선택적 약물전달용 조성물
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
KR20000011247A (ko) * 1998-07-23 2000-02-25 김윤 다당류를이용한대장선택성약물전달조성물및약학제제
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
DE60131177T2 (de) 2000-09-06 2008-08-07 AP Pharma, Inc., Redwood Abbaubare polyacetal-polymere
GB2367002A (en) * 2000-09-25 2002-03-27 British Sugar Plc Coating composition
US6590059B2 (en) 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
US6524606B1 (en) 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
DE10209979A1 (de) * 2002-03-07 2003-09-25 Ratiopharm Gmbh Arzneimittel mit Cholesterolspiegel-senkenden Wirkstoffen mit zeitverzögerter Wirkstofffreisetzung
JP5740306B2 (ja) 2008-10-03 2015-06-24 ドクトル ファルク ファルマ ゲーエムベーハー メサラミン顆粒を用いて腸疾患を治療するための組成物および方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3405378A1 (de) * 1984-02-15 1985-08-22 Röhm GmbH, 6100 Darmstadt Arzneimittelueberzug
DE3827561C1 (es) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
FR2663222A1 (fr) * 1990-06-13 1991-12-20 Medgenix Group Sa Microcapsule de liquide huileux.

Also Published As

Publication number Publication date
DK0485840T4 (da) 1999-10-04
EP0485840B2 (de) 1999-03-03
EP0485840A2 (de) 1992-05-20
DE59104870D1 (de) 1995-04-13
DK0485840T3 (da) 1995-06-06
EP0485840B1 (de) 1995-03-08
ATE119389T1 (de) 1995-03-15
EP0485840A3 (en) 1992-11-25
ES2071889T3 (es) 1995-07-01
DE9015551U1 (de) 1992-03-12

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