ES2072010T3 - Procedimiento para la preparacion de piridinas sustituidas via 1-aza-1,3-butadienos y productos intermedios de 1-aza-1,3-butadieno. - Google Patents

Procedimiento para la preparacion de piridinas sustituidas via 1-aza-1,3-butadienos y productos intermedios de 1-aza-1,3-butadieno.

Info

Publication number
ES2072010T3
ES2072010T3 ES91914662T ES91914662T ES2072010T3 ES 2072010 T3 ES2072010 T3 ES 2072010T3 ES 91914662 T ES91914662 T ES 91914662T ES 91914662 T ES91914662 T ES 91914662T ES 2072010 T3 ES2072010 T3 ES 2072010T3
Authority
ES
Spain
Prior art keywords
aza
butadiene
piridines
substituted
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91914662T
Other languages
English (en)
Inventor
Anna Maria Cornelia Castelijns
Henricus Johannes Arts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Application granted granted Critical
Publication of ES2072010T3 publication Critical patent/ES2072010T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/08—Preparation by ring-closure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C251/16—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/36—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/40—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/08—Preparation by ring-closure
    • C07D213/09—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/08—Preparation by ring-closure
    • C07D213/09—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles
    • C07D213/12—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles from unsaturated compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)

Abstract

PROCESO PARA LA PREPARACION DE PIRIDINAS SUSTITUIDAS PERMITIENDO QUE LOS 1-AZA-1,3-BUTADIENOS REACCIONEN, EN PRESENCIA DE UNA CANTIDAD CATALITICA DE AMINA SECUNDARIA Y ACIDO, CON UN ALDEHIDO O CETONA, Y NUEVOS 1-AZA-1,3-BUTADIENOS QUE SE USAN EN ESTE PROCESO. DICHAS PIRIDINAS SE PUEDEN OBTENER CON UN GRAN RENDIMIENTO EN UN PROCESO SIMPLE CON UN CORTO PERIODO DE REACCION. EL 1-AZA-1,3-BUTADIENO SE PUEDE, SI ASI SE DESEA, PREPARAR IN SITU A PARTIR DE UNA IMINA Y UN ALDEHIDO.
ES91914662T 1990-08-08 1991-08-07 Procedimiento para la preparacion de piridinas sustituidas via 1-aza-1,3-butadienos y productos intermedios de 1-aza-1,3-butadieno. Expired - Lifetime ES2072010T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9001786A NL9001786A (nl) 1990-08-08 1990-08-08 Werkwijze voor de bereiding van gesubstitueerde pyridines via 1-aza-1,3-butadienen en de tussenprodukten 1-aza-1,3-butadienen.

Publications (1)

Publication Number Publication Date
ES2072010T3 true ES2072010T3 (es) 1995-07-01

Family

ID=19857526

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91914662T Expired - Lifetime ES2072010T3 (es) 1990-08-08 1991-08-07 Procedimiento para la preparacion de piridinas sustituidas via 1-aza-1,3-butadienos y productos intermedios de 1-aza-1,3-butadieno.

Country Status (8)

Country Link
US (1) US5438143A (es)
EP (1) EP0543880B1 (es)
JP (1) JP3065349B2 (es)
AU (1) AU8394191A (es)
DE (1) DE69109121T2 (es)
ES (1) ES2072010T3 (es)
NL (1) NL9001786A (es)
WO (1) WO1992002505A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520274A (ja) 2000-01-18 2003-07-02 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 反応触媒としてのイミダゾリジノンの酸付加塩
US6369243B1 (en) 2000-01-18 2002-04-09 The Regents Of The Univerisity Of California Chemical transformation of substrates using nonmetallic, organic catalyst compositions
US7173139B2 (en) 2001-06-29 2007-02-06 California Institute Of Technology Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts
US6784323B2 (en) 2001-06-29 2004-08-31 California Institute Of Technology Enantioselective transformation of α,β-unsaturated aldehydes using chiral organic catalysts
ATE391713T1 (de) 2001-12-05 2008-04-15 California Inst Of Techn Enantioseletive umwandlung von alpha,beta- ungesättigten ketonen unter verwendung chiraler organischer katalysatoren
WO2003089396A1 (en) 2002-04-19 2003-10-30 California Institute Of Technology Direct, enantioselective aldol coupling of aldehydes using chiral organic catalysts
US7323604B2 (en) 2004-11-19 2008-01-29 California Institute Of Technology Hydride reduction of α,β-unsaturated carbonyl compounds using chiral organic catalysts
CN111518021B (zh) * 2020-06-08 2021-08-27 沅江华龙催化科技有限公司 一种利用混合苯乙烯衍生物与n,n-二甲基甲酰胺构建3,5-二取代吡啶的方法

Also Published As

Publication number Publication date
JPH05509319A (ja) 1993-12-22
NL9001786A (nl) 1992-03-02
DE69109121D1 (de) 1995-05-24
AU8394191A (en) 1992-03-02
JP3065349B2 (ja) 2000-07-17
DE69109121T2 (de) 1995-11-30
WO1992002505A1 (en) 1992-02-20
EP0543880A1 (en) 1993-06-02
EP0543880B1 (en) 1995-04-19
US5438143A (en) 1995-08-01

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