ES2073196T3 - Dispositivo y metodo para renovar electrodos durante la iontoforesis. - Google Patents

Dispositivo y metodo para renovar electrodos durante la iontoforesis.

Info

Publication number
ES2073196T3
ES2073196T3 ES92101754T ES92101754T ES2073196T3 ES 2073196 T3 ES2073196 T3 ES 2073196T3 ES 92101754 T ES92101754 T ES 92101754T ES 92101754 T ES92101754 T ES 92101754T ES 2073196 T3 ES2073196 T3 ES 2073196T3
Authority
ES
Spain
Prior art keywords
electrode
active agent
electrolyte
supply
electrodes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92101754T
Other languages
English (en)
Inventor
Burton H Sage Jr
Carl R Bock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2073196T3 publication Critical patent/ES2073196T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Control Of El Displays (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN DISPOSITIVO EXPENDEDOR DE MEDICAMENTOS IONTOFORETICOS QUE TIENEN CARACTERISTICAS DE RENOVACION DE ELECTRODOS QUE COMPRENDE UN ALOJAMIENTO QUE TIENE UN PRIMER ELECTRODO, UN SEGUNDO ELECTRODO, UN CIRCUITO PARA SUMINISTRAR COMUNICACION ELECTRICA ENTRE EL PRIMER Y EL SEGUNDO ELECTRODO. EL CIRCUITO ES CAPAZ DE ACOPLARSE A UNA FUENTE DE CORRIENTE. SE PREVEN MEDIOS DE CONTROL PARA DETERMINAR LA CANTIDAD DE CORRIENTE QUE PASA ENTRE LOS ELECTRODOS. UN DEPOSITO DE ELECTROLITO AMOVIBLE PUEDE CONTENER EL ELECTROLITO Y ACOPLAR AMOVIBLEMENTE EL ALOJAMIENTO DE MANERA QUE UNO DE LOS ELECTRODOS PUEDA PONERSE EN CONTACTO CON EL ELECTROLITO CONTENIDO DENTRO DEL DEPOSITO. UN DEPOSITO DE AGENTE ACTIVO AMOVIBLE PUEDE CONTENER UN AGENTE ACTIVO PARA SUMINISTRO IONTOFORETICO. EL DEPOSITO DE AGENTE ACTIVO PUEDE ACOPLARSE AMOVIBLEMENTE AL ALOJAMIENTO DE MANERA QUE EL AGENTE ACTIVO CONTACTE CON UNO DE LOS ELECTRODOS. LA PRESENTE INVENCION TAMBIEN SE REFIERE A UN METODO PARA RENOVAR ELECTRODOS DURANTE EL SUMINISTRO DE UN AGENTE ACTIVO DESDE UN SISTEMA IONTOFERICO QUE COMPRENDE AL MENOS DOS ELECTRODOS Y MEDIOS PARA CONTENER UN AGENTE ACTIVO, DICHO METODO COMPRENDE: A) EL SUMINISTRO DE UN AGENTE ACTIVO EN CONEXION CON UN PRIMER ELECTRODO QUE COMPLETA UN CIRCUITO CON UN SEGUNDO ELECTRODO EN CONEXION CON UN ELECTROLITO, Y B) EL SUMINISTRO DE UN AGENTE ACTIVO A PARTIR DEL SEGUNDO ELECTRODO SUSTITUYENDO EL ELECTROLITO CON UN AGENTE ACTIVO EN CONEXION CON EL SEGUNDO ELECTRODO Y SUSTITUYENDO EL AGENTE ACTIVO CON UN ELECTROLITO EN CONEXION CON EL PRIMER ELECTRODO.
ES92101754T 1991-02-08 1992-02-04 Dispositivo y metodo para renovar electrodos durante la iontoforesis. Expired - Lifetime ES2073196T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/652,855 US5320597A (en) 1991-02-08 1991-02-08 Device and method for renewing electrodes during iontophoresis

Publications (1)

Publication Number Publication Date
ES2073196T3 true ES2073196T3 (es) 1995-08-01

Family

ID=24618454

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92101754T Expired - Lifetime ES2073196T3 (es) 1991-02-08 1992-02-04 Dispositivo y metodo para renovar electrodos durante la iontoforesis.

Country Status (16)

Country Link
US (1) US5320597A (es)
EP (1) EP0498353B1 (es)
JP (1) JPH067868B2 (es)
KR (1) KR940006528B1 (es)
AT (1) ATE123660T1 (es)
AU (1) AU644917B2 (es)
BR (1) BR9105499A (es)
CA (1) CA2056015C (es)
DE (1) DE69202872T2 (es)
DK (1) DK0498353T3 (es)
ES (1) ES2073196T3 (es)
FI (1) FI920534A7 (es)
GR (1) GR3017405T3 (es)
IE (1) IE67142B1 (es)
MX (1) MX9200176A (es)
NO (1) NO914893L (es)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238381B1 (en) * 1990-11-01 2001-05-29 Robert Tapper Iontophoretic treatment system
HUT65957A (en) † 1992-03-17 1994-08-29 Becton Dickinson Co User operated iontophoretical device and method for manufacturing it
JP2542792B2 (ja) * 1992-11-05 1996-10-09 ベクトン・ディッキンソン・アンド・カンパニー ユ―ザ作動型のイオン導入式装置
US5445609A (en) * 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
CA2126487C (en) * 1993-06-23 2001-05-29 Keiichiro Okabe Iontophoresis device
FR2709670B1 (fr) * 1993-09-10 1995-10-20 Asulab Sa Dispositif en trois modules pour l'administration transdermique de médicaments par électrophorèse ou iontophorèse.
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
JP2716361B2 (ja) * 1994-02-16 1998-02-18 株式会社アドバンス 生体用プリント電極
AU2682795A (en) * 1994-06-17 1996-01-15 Hisamitsu Pharmaceutical Co., Inc. Electrode for iontophoresis and device using the same
US5562607A (en) * 1995-01-18 1996-10-08 Alza Corporation Electrotransport device having reusable controller power saver
FR2729574B1 (fr) * 1995-01-24 1997-07-04 Sanofi Sa Dispositif d'ionophorese pour l'administration transcutanee d'un principe actif de type oligosaccharide anionique
FR2729575B1 (fr) * 1995-01-24 1997-07-04 Elf Aquitaine Dispositif d'ionophorese pour l'administration transcutanee d'un principe actif de type glycosaminoglycane anionique de basse masse moleculaire
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
JPH11505158A (ja) * 1995-05-15 1999-05-18 アルザ・コーポレーション 再使用可能なコントローラを有する電気輸送装置
US6216033B1 (en) 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6425892B2 (en) 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
DE122006000022I1 (de) 1995-06-05 2006-09-21 Alza Corp Vorrichtung zur Transdermalen iontophoretischen verabreichung von Fentanyl und Sufentanil
US6881208B1 (en) 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
IE960375A1 (en) * 1995-06-05 1996-12-11 Alza Corp Device for transdermal electrotransport delivery of fentanyl¹and sufentanil
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US6355025B1 (en) 1995-06-07 2002-03-12 Alza Corporation Adjustable electrotransport drug delivery using a fixed output controller
CA2223588C (en) * 1995-06-07 2004-01-06 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
WO1997018855A1 (en) * 1995-11-21 1997-05-29 Eduard Naumovich Lerner Device for enhanced delivery of biologically active substances and compounds in an organism
WO1997024157A1 (en) * 1995-12-28 1997-07-10 Becton, Dickinson And Company Molecules for iontophoretic delivery
AU3404197A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
US5792097A (en) * 1996-09-27 1998-08-11 Becton Dickinson And Company Iontophoretic electrodes and surface active agents
US6018679A (en) * 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
JP3366548B2 (ja) * 1997-02-26 2003-01-14 久光製薬株式会社 イオントフォレーシス用デバイス構造体及びその製造方法
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US5846217A (en) * 1997-07-29 1998-12-08 Iomed, Inc. Iontophoretic bioelectrode and method of using same
WO1999018797A1 (en) 1997-10-09 1999-04-22 Emory University Method and devices for transdermal delivery of lithium
US6295469B1 (en) 1997-11-14 2001-09-25 Alza Corporation Formulation for electrically assisted delivery of lidocaine and epinephrine
ATE274973T1 (de) 1998-01-28 2004-09-15 Alza Corp Electrochemisch reaktive kathode für elektrotransport gerät
JPH11239621A (ja) * 1998-02-25 1999-09-07 Hisamitsu Pharmaceut Co Inc イオントフォレーシス装置
US6858018B1 (en) * 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
US20070196490A1 (en) * 1999-01-22 2007-08-23 Powderject Research Limited Method of enhancing needleless transdermal powered drug delivery
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
AU761949B2 (en) * 1999-04-13 2003-06-12 Hisamitsu Pharmaceutical Co. Inc. Iontophoresis device
US7520875B2 (en) * 2001-04-06 2009-04-21 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US7083580B2 (en) * 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
FR2830766B1 (fr) 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese transpalpebrale
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
US6975902B2 (en) * 2002-06-28 2005-12-13 Alza Corporation Reservoir and a series of related reservoirs for use in an electrotransport drug delivery device and devices comprised thereof
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
CA2587780A1 (en) * 2004-11-18 2006-05-26 Transpharma Medical Ltd. Combined micro-channel generation and iontophoresis for transdermal delivery of pharmaceutical agents
WO2006133102A2 (en) * 2005-06-03 2006-12-14 Trans-Dermal Patents Company, Llc Agent delivery system and uses of the same
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
KR20080047600A (ko) 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
EP1965858A2 (en) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. System and method for remote based control of an iontophoresis device
WO2007088897A1 (ja) * 2006-01-31 2007-08-09 Tti Ellebeau, Inc. カートリッジ型イオントフォレーシス装置
JP2007229003A (ja) * 2006-02-27 2007-09-13 Transcutaneous Technologies Inc イオントフォレーシス装置
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
JP4934405B2 (ja) * 2006-11-02 2012-05-16 株式会社Ｊｉｕ−Ｋｉｄｄ イオントフォレーシスによる投与方法及び装置
KR20090106492A (ko) 2006-12-01 2009-10-09 티티아이 엘뷰 가부시키가이샤 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법
US20080234627A1 (en) * 2007-03-22 2008-09-25 Wanda Dent Pivotally engaged multiple part electrotransport drug delivery device
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
EP2043733A1 (en) 2007-06-26 2009-04-08 Alza Corporation Methods and devices for transdermal electrotransport delivery of lofentanil and carfentanil
ES2454974T3 (es) 2007-06-27 2014-04-14 The General Hospital Corporation Aparato para la inhibición óptica de la terapia fotodinámica
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
USD588274S1 (en) 2008-02-12 2009-03-10 Alza Corporation Skin-adhering drug delivery patch
US20090312689A1 (en) * 2008-06-05 2009-12-17 Alza Corporation Adjustable Current Electrotransport Fentanyl Delivery Device
KR101674904B1 (ko) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 중재형 약물전달 시스템과 그 방법
JP5463136B2 (ja) * 2009-12-22 2014-04-09 帝國製薬株式会社 イオントフォレーシス療法に用いる電極装置
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
USD699855S1 (en) 2012-11-12 2014-02-18 Incline Therapeutics, Inc. Iontophoretic drug delivery device
US9744353B2 (en) * 2012-11-14 2017-08-29 Teva Pharmaceuticals International Gmbh Detection of presence and alignment of a therapeutic agent in an iontophoretic drug delivery device
CN112691290A (zh) * 2019-10-23 2021-04-23 上海钛医医疗科技有限公司 离子电渗透给药装置

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4019510A (en) * 1975-02-10 1977-04-26 Sybron Corporation Therapeutic method of using low intensity direct current generator with polarity reversal
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4177817A (en) * 1978-02-01 1979-12-11 C. R. Bard, Inc. Dual terminal transcutaneous electrode
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
JPS62139672A (ja) * 1985-12-14 1987-06-23 林原　健 正負イオントホレ−ゼ用治療器
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4886489A (en) * 1986-03-19 1989-12-12 Jacobsen Stephen C Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
JPS63145669A (ja) * 1986-10-11 1988-06-17 林原　健 正、負イオントホレ−ゼ用スイッチ
US5013293A (en) * 1987-05-28 1991-05-07 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5037381A (en) * 1990-07-27 1991-08-06 Bock C Randolph Electrically assisted transdermal transport device and method for renewing the device

Also Published As

Publication number Publication date
IE914079A1 (en) 1992-08-12
IE67142B1 (en) 1996-03-06
EP0498353A2 (en) 1992-08-12
JPH067868B2 (ja) 1994-02-02
DE69202872D1 (de) 1995-07-20
FI920534A0 (fi) 1992-02-07
US5320597A (en) 1994-06-14
AU8895391A (en) 1992-08-13
AU644917B2 (en) 1993-12-23
EP0498353A3 (en) 1992-09-23
NO914893D0 (no) 1991-12-12
KR920016113A (ko) 1992-09-24
GR3017405T3 (en) 1995-12-31
MX9200176A (es) 1992-08-01
JPH04312471A (ja) 1992-11-04
DE69202872T2 (de) 1995-11-02
BR9105499A (pt) 1992-10-27
EP0498353B1 (en) 1995-06-14
CA2056015C (en) 1995-04-11
CA2056015A1 (en) 1992-08-09
FI920534A7 (fi) 1992-08-09
NO914893L (no) 1992-08-10
KR940006528B1 (ko) 1994-07-21
ATE123660T1 (de) 1995-06-15
DK0498353T3 (da) 1995-10-02

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