ES2073512T3 - Cristales de nitrofurantoina. - Google Patents
Cristales de nitrofurantoina.Info
- Publication number
- ES2073512T3 ES2073512T3 ES90201965T ES90201965T ES2073512T3 ES 2073512 T3 ES2073512 T3 ES 2073512T3 ES 90201965 T ES90201965 T ES 90201965T ES 90201965 T ES90201965 T ES 90201965T ES 2073512 T3 ES2073512 T3 ES 2073512T3
- Authority
- ES
- Spain
- Prior art keywords
- particulates
- nitrofurantoin
- nitrofurantoine
- crystals
- monohydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- NXFQHRVNIOXGAQ-YCRREMRBSA-N nitrofurantoin Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)NC(=O)C1 NXFQHRVNIOXGAQ-YCRREMRBSA-N 0.000 title abstract 6
- 239000013078 crystal Substances 0.000 title 1
- 229960000564 nitrofurantoin Drugs 0.000 abstract 7
- NHBPVLAHAVEISO-JSGFVSQVSA-N 1-[(e)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione;hydrate Chemical compound O.O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)NC(=O)C1 NHBPVLAHAVEISO-JSGFVSQVSA-N 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
NITROFURANTOINA PARTICULADA QUE COMPRENDE PARTICULAS DISCRETAS DE NITROFURANTIONA EN LA QUE: A) DICHAS PARTICULAS SON MAYORES DE 200 MALLAS; B) EL AREA SUPERFICIAL BET DE DICHAS PARTICULAS ES DE MENOS 0.2 M (AL CUADRADO) /G. PREFERENTEMENTE, LA SUPERFICIE DE DICHOS PARTICULADOS CONSISTE ESENCIALMENTE EN MONOHIDRATO DE NITROFURANTOINA. TAMBIEN, PREFERENTEMENTE, DICHOS PARTICULADOS COMPRENDEN AL MENOS 5% PREFERENTEMENTE 50% DE MONOHIDRATO DE NITROFURANTOINA. LAS COMPOSICIONES REFERIDAS A ESTA INVENCION, COMPRENDEN ESTOS GRANULADOS EN SUSPENSION ACUOSA Y SON ALTAMENTE EFICACES PARA DOSIFICARLAS EN FORMA ORAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38605089A | 1989-07-26 | 1989-07-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2073512T3 true ES2073512T3 (es) | 1995-08-16 |
Family
ID=23523951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90201965T Expired - Lifetime ES2073512T3 (es) | 1989-07-26 | 1990-07-18 | Cristales de nitrofurantoina. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0412592B1 (es) |
| AT (1) | ATE124041T1 (es) |
| AU (1) | AU641411B2 (es) |
| CA (1) | CA2020813C (es) |
| DE (1) | DE69020257T2 (es) |
| DK (1) | DK0412592T3 (es) |
| ES (1) | ES2073512T3 (es) |
| IE (1) | IE67044B1 (es) |
| IL (1) | IL95058A (es) |
| NZ (1) | NZ234636A (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2221788C2 (ru) * | 1991-08-14 | 2004-01-20 | Проктер энд Гэмбл Фармасьютикалз | Оксоциклические соединения мочевины, фармацевтическая композиция, способ лечения |
| KR101974412B1 (ko) | 2018-02-28 | 2019-05-02 | 보령제약 주식회사 | 약학적 제제 및 이의 제조방법 |
| CN110776499A (zh) * | 2019-09-27 | 2020-02-11 | 济南金达药化有限公司 | 呋喃妥因一水合物晶体的制备方法以及呋喃妥因一水合物晶体 |
| CN117771201A (zh) * | 2023-09-28 | 2024-03-29 | 浙江普洛康裕制药有限公司 | 一种呋喃妥因大晶体胶囊及其制备工艺 |
-
1990
- 1990-07-10 CA CA002020813A patent/CA2020813C/en not_active Expired - Lifetime
- 1990-07-12 IL IL9505890A patent/IL95058A/en not_active IP Right Cessation
- 1990-07-18 EP EP90201965A patent/EP0412592B1/en not_active Expired - Lifetime
- 1990-07-18 AT AT90201965T patent/ATE124041T1/de not_active IP Right Cessation
- 1990-07-18 DK DK90201965.2T patent/DK0412592T3/da active
- 1990-07-18 DE DE69020257T patent/DE69020257T2/de not_active Expired - Fee Related
- 1990-07-18 ES ES90201965T patent/ES2073512T3/es not_active Expired - Lifetime
- 1990-07-24 IE IE269290A patent/IE67044B1/en not_active IP Right Cessation
- 1990-07-24 AU AU59753/90A patent/AU641411B2/en not_active Ceased
- 1990-07-24 NZ NZ234636A patent/NZ234636A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL95058A (en) | 1995-03-30 |
| DE69020257T2 (de) | 1995-12-21 |
| IL95058A0 (en) | 1991-06-10 |
| CA2020813C (en) | 1995-08-01 |
| EP0412592B1 (en) | 1995-06-21 |
| DK0412592T3 (da) | 1995-08-14 |
| EP0412592A1 (en) | 1991-02-13 |
| ATE124041T1 (de) | 1995-07-15 |
| NZ234636A (en) | 1993-08-26 |
| IE902692A1 (en) | 1991-02-27 |
| DE69020257D1 (de) | 1995-07-27 |
| AU5975390A (en) | 1991-09-30 |
| AU641411B2 (en) | 1993-09-23 |
| IE67044B1 (en) | 1996-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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