ES2074563T3 - Procedimiento de preparacion de compuestos y metodo para el tratamiento de la septicemia y/o el choque septico. - Google Patents
Procedimiento de preparacion de compuestos y metodo para el tratamiento de la septicemia y/o el choque septico.Info
- Publication number
- ES2074563T3 ES2074563T3 ES90902432T ES90902432T ES2074563T3 ES 2074563 T3 ES2074563 T3 ES 2074563T3 ES 90902432 T ES90902432 T ES 90902432T ES 90902432 T ES90902432 T ES 90902432T ES 2074563 T3 ES2074563 T3 ES 2074563T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- gram
- septic shock
- negative bacteria
- septicemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 4
- 206010040070 Septic Shock Diseases 0.000 title abstract 3
- 230000036303 septic shock Effects 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- 206010040047 Sepsis Diseases 0.000 title 1
- 239000002131 composite material Substances 0.000 title 1
- 208000013223 septicemia Diseases 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 239000002158 endotoxin Substances 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000245772 Gasteria Species 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000027096 gram-negative bacterial infections Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
COMPOSICIONES FARMACEUTICAS USADAS PARA EL TRATAMIENTO O PROFILAXIS DE ATAQUES DE BACTERIAS GRAM-NEGATIVAS O DE CHOQUES SEPTICOS, QUE CONTIENEN UNA CANTIDAD SUFICIENTE ANTIBACTERIANA DE INMUNOGLOBULINAS POLICLONICAS CONTRA BACTERIAS GRAM-NEGATIVAS Y UNA CANTIDAD EFECTIVA DE PROTEINA C PARA DISOLVER COAGULOS EN LA SANGRE. LAS COMPOSICIONES PUEDEN CONTENER ADEMAS UNO O MAS COFACTORES DE PROTEINA C Y ANTICUERPOS MONOCLONICOS CONTRA ENDOTOXINAS DE BACTERIAS GRAM-NEGATIVAS. UN METODO PARA EL TRATAMIENTO O PROFILAXIS DE INFECCIONES BACTERIANAS GRAM-NEGATIVAS, O DE CHOQUES SEPTICOS, COMPRENDE LA ADMINISTRACION, JUNTOS O POR SEPARADO, DE UNA CANTIDAD ANTIBACTERIANA EFECTIVA DE INMUNOGLOBULINAS POLICLONICAS CONTRA BACTERIAS GRAM-NEGATIVAS Y DE UNA CANTIDAD EFECTIVA DE PROTEINA C PARA DISOLVER COAGULOS SANGUINEOS. EL METODO PUEDE INCLUIR OPCIONALMENTE ADMINISTRAR UNO O MAS COFACTORES DE PROTEINA C Y ANTICUERPOS MONOCLONICOS CONTRA ENDOTOXINAS DE BACTERIAS GRAM-NEGATIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/300,836 US5093117A (en) | 1989-01-24 | 1989-01-24 | Compositions and method for the treatment or prophylaxis of sepsis or septic shock |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2074563T3 true ES2074563T3 (es) | 1995-09-16 |
Family
ID=23160797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90902432T Expired - Lifetime ES2074563T3 (es) | 1989-01-24 | 1990-01-17 | Procedimiento de preparacion de compuestos y metodo para el tratamiento de la septicemia y/o el choque septico. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5093117A (es) |
| EP (1) | EP0406398B1 (es) |
| JP (1) | JP3038006B2 (es) |
| CA (1) | CA1339990C (es) |
| DE (1) | DE69019072T2 (es) |
| DK (1) | DK0406398T3 (es) |
| ES (1) | ES2074563T3 (es) |
| WO (1) | WO1990008556A1 (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571786A (en) * | 1990-08-16 | 1996-11-05 | Immuno Aktiengesellschaft | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
| AT402260B (de) * | 1990-08-16 | 1997-03-25 | Immuno Ag | Protein c-hältige pharmazeutische präparation |
| AT397615B (de) * | 1991-05-14 | 1994-05-25 | Immuno Ag | Arzneimittel enthaltend protein c |
| EP0651655A4 (en) | 1992-07-24 | 1996-05-29 | Oklahoma Med Res Found | REDUCTION OF MICROVASCULAR BLEEDING DURING SURGERY BY BLOCKING PROTEIN C ACTIVATION |
| AU1096595A (en) * | 1993-11-12 | 1995-05-29 | Gilead Sciences, Inc. | Thrombin mutants |
| US7060484B1 (en) | 1993-11-12 | 2006-06-13 | Gilead Sciences, Inc. | Polypeptides and coagulation therapy |
| US5580856A (en) * | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
| US20060127387A1 (en) * | 1997-04-22 | 2006-06-15 | Zikria Bashir A | Compositions based on polysaccharides and protein C and methods of using the same for preventing and treating sepsis and other conditions |
| US6630137B1 (en) | 1997-04-28 | 2003-10-07 | Eli Lilly And Company | Activated protein C formulations |
| CZ298429B6 (cs) * | 1997-04-28 | 2007-10-03 | Eli Lilly And Company | Stabilní lyofilizovaný prostredek |
| DE19726248C2 (de) * | 1997-06-20 | 2000-03-02 | Mucos Pharma Gmbh & Co | Verwendung proteolytischer Enzyme und Rutosid zur Behandlung von septischem Schock |
| US6953568B1 (en) | 1998-08-25 | 2005-10-11 | Oklahoma Medical Research Foundation | Targeting of molecules to large vessel endothelium using EPCR |
| CN1324244A (zh) * | 1998-10-22 | 2001-11-28 | 伊莱利利公司 | 治疗脓毒症的方法 |
| AU1940800A (en) * | 1998-12-21 | 2000-07-12 | Eli Lilly And Company | Combination therapy for the treatment of sepsis |
| US6679870B1 (en) | 1999-07-23 | 2004-01-20 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US6685694B2 (en) | 1999-07-23 | 2004-02-03 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US20030158111A1 (en) * | 1999-10-01 | 2003-08-21 | David Bar-Or | Methods and products for oral care |
| US7204981B2 (en) * | 2000-03-28 | 2007-04-17 | Eli Lilly And Company | Methods of treating diseases with activated protein C |
| AU2001262939A1 (en) | 2000-05-24 | 2001-12-03 | Eli Lilly And Company | Formulations and use of activated protein c and protein c zymogen for treating hypercoagulable states |
| PL214224B1 (pl) * | 2001-01-30 | 2013-07-31 | Lauridsen Group | Doustna forma koncentratu nie - hiperimmunizowanych nie-specyficznych immunoglobulin oraz suplement diety |
| US20030190314A1 (en) * | 2001-01-30 | 2003-10-09 | The Lauridsen Group | Methods and compositions of treatment for modulating the immune system of animals |
| BR0206869A (pt) * | 2001-01-30 | 2007-01-02 | Lauridsen Group Inc | método para o tratamento de um animal sofrendo de um estado doentio de disfunção imune associado com nìveis alterados de igg ou tnf-delta, composição farmacêutica para o tratamento de distúrbios auto-imunes associados com elevados igg e/ou tnf-delta ou para a potenciação de protocolos de vacina, e método para o tratamento de estado doentio associado com disfunção imune em um animal |
| JP2004535461A (ja) * | 2001-07-19 | 2004-11-25 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | プロテインcの不活性化を抑制するための銅キレート剤の使用 |
| EP1485121A4 (en) * | 2002-03-08 | 2007-11-07 | Lilly Co Eli | ACTIVE C PROTEIN FORMULATIONS |
| US7160636B2 (en) | 2002-09-13 | 2007-01-09 | Nec Tokin Corporation | Ferrite thin film, method of manufacturing the same and electromagnetic noise suppressor using the same |
| EP2266606B1 (en) | 2003-05-15 | 2014-09-10 | Genentech, Inc. | Methods and compositions for the prevention and treatment of sepsis |
| AU2005313971B2 (en) * | 2004-12-08 | 2011-10-13 | Immunomedics, Inc. | Methods and compositions for immunotherapy and detection of inflammatory and immune-dysregulatory disease, infectious disease, pathologic angiogenesis and cancer |
| US8834862B2 (en) * | 2005-04-19 | 2014-09-16 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent |
| ITFI20070063A1 (it) * | 2007-03-15 | 2008-09-16 | Kedrion Spa | Concentrato di proteina c contenente proteina s, sua preparazione ed uso. |
| JP6273272B2 (ja) | 2012-07-04 | 2018-01-31 | ジージー バイオテック エルエルシー | 炎症性皮膚障害の治療 |
| JP2017513944A (ja) | 2014-04-16 | 2017-06-01 | ジージー バイオテック エルエルシー | 異常な皮膚瘢痕化の治療 |
| CA2946032C (en) | 2014-04-16 | 2022-06-14 | Zz Biotech Llc | Use of apc analogue for wound healing |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4587121A (en) * | 1983-06-14 | 1986-05-06 | Miles Laboratories, Inc. | High titer Pseudomonas immune serum globulin |
| GB8319538D0 (en) * | 1983-07-20 | 1983-08-24 | Beecham Group Plc | Compounds |
| US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
| DE3516119A1 (de) * | 1985-05-04 | 1986-11-06 | Biotest Pharma GmbH, 6000 Frankfurt | Polyvalentes hyperimmunglobulin-praeparat |
| US5258288A (en) * | 1986-07-25 | 1993-11-02 | Genzyme Corporation | Vector containing DNA encoding mature human protein S |
-
1989
- 1989-01-24 US US07/300,836 patent/US5093117A/en not_active Expired - Lifetime
- 1989-09-29 CA CA000615182A patent/CA1339990C/en not_active Expired - Fee Related
-
1990
- 1990-01-17 EP EP90902432A patent/EP0406398B1/en not_active Expired - Lifetime
- 1990-01-17 DE DE69019072T patent/DE69019072T2/de not_active Expired - Fee Related
- 1990-01-17 WO PCT/US1990/000215 patent/WO1990008556A1/en not_active Ceased
- 1990-01-17 DK DK90902432.5T patent/DK0406398T3/da active
- 1990-01-17 ES ES90902432T patent/ES2074563T3/es not_active Expired - Lifetime
- 1990-01-17 JP JP02502465A patent/JP3038006B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3038006B2 (ja) | 2000-05-08 |
| EP0406398A4 (en) | 1991-07-03 |
| EP0406398A1 (en) | 1991-01-09 |
| CA1339990C (en) | 1998-08-11 |
| DE69019072T2 (de) | 1995-11-30 |
| US5093117A (en) | 1992-03-03 |
| WO1990008556A1 (en) | 1990-08-09 |
| DE69019072D1 (de) | 1995-06-08 |
| DK0406398T3 (da) | 1995-07-17 |
| JPH03503536A (ja) | 1991-08-08 |
| EP0406398B1 (en) | 1995-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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