ES2075437T3 - Nuevo derivado del acido cafeico, el oraposido, composicion cosmetica o farmaceutica, particularmente dermatologica que lo contiene. - Google Patents
Nuevo derivado del acido cafeico, el oraposido, composicion cosmetica o farmaceutica, particularmente dermatologica que lo contiene.Info
- Publication number
- ES2075437T3 ES2075437T3 ES91907075T ES91907075T ES2075437T3 ES 2075437 T3 ES2075437 T3 ES 2075437T3 ES 91907075 T ES91907075 T ES 91907075T ES 91907075 T ES91907075 T ES 91907075T ES 2075437 T3 ES2075437 T3 ES 2075437T3
- Authority
- ES
- Spain
- Prior art keywords
- new derivative
- pct
- oraposide
- cosmetic
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FPOYEEKZOOLVJA-UHFFFAOYSA-N Crenatoside Natural products OC1C(O)C(O)C(C)OC1OC1C2OC(C=3C=C(O)C(O)=CC=3)COC2OC(CO)C1OC(=O)C=CC1=CC=C(O)C(O)=C1 FPOYEEKZOOLVJA-UHFFFAOYSA-N 0.000 title abstract 2
- FPOYEEKZOOLVJA-DNBQVIFESA-N [(4ar,6r,7r,8s,8as)-2-(3,4-dihydroxyphenyl)-6-(hydroxymethyl)-8-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3,4a,6,7,8,8a-hexahydro-2h-pyrano[2,3-b][1,4]dioxin-7-yl] (e)-3-(3,4-dihydroxyphenyl)prop-2-enoate Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H]2OC(C=3C=C(O)C(O)=CC=3)CO[C@@H]2O[C@H](CO)[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 FPOYEEKZOOLVJA-DNBQVIFESA-N 0.000 title abstract 2
- 239000002537 cosmetic Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical class OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Abstract
LA INVENCION CONCIERNE A UN NUEVO DERIVADO DEL ACIDO CAFEICO. ESTE NUEVO DERIVADO PRESENTA LA FORMULA (I) EN LA CUAL UNO O VARIOS R REPRESENTAN INDEPENDIENTEMENTE UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO EN C1-C5, EN PARTICULAR METILO, UN GRUPO ACILO, EN PARTICULAR EN C1-C6, SOBRE TODO ACETILO. ESTE NUEVO DERIVADO DENOMINADO ORAPOXIDO ES PARTICULARMENTE UTIL PARA LA PREPARACION DE COMPOSICIONES COSMETICAS O FARMACEUTICAS, EN PARTICULAR DERMATOLOGICAS, GRACIAS SOBRE TODO A UNA ACTIVIDAD ANTIRADICALES LIBRES, ANTIINFLAMATORIAS Y ANTIENVEJECIMIENTO ACTINICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/FR1991/000229 WO1992016544A1 (fr) | 1991-03-21 | 1991-03-21 | Nouveau derive de l'acide cafeique, l'oraposide, composition cosmetique ou pharmaceutique, notamment dermatologique le contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2075437T3 true ES2075437T3 (es) | 1995-10-01 |
Family
ID=34834297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91907075T Expired - Lifetime ES2075437T3 (es) | 1991-03-21 | 1991-03-21 | Nuevo derivado del acido cafeico, el oraposido, composicion cosmetica o farmaceutica, particularmente dermatologica que lo contiene. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5719129A (es) |
| EP (1) | EP0576420B1 (es) |
| JP (1) | JP3147900B2 (es) |
| KR (1) | KR100194830B1 (es) |
| AT (1) | ATE123287T1 (es) |
| AU (1) | AU670742B2 (es) |
| CA (1) | CA2102689A1 (es) |
| DE (1) | DE69110136T2 (es) |
| ES (1) | ES2075437T3 (es) |
| WO (1) | WO1992016544A1 (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4444238A1 (de) * | 1994-12-13 | 1996-06-20 | Beiersdorf Ag | Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden |
| DE19615575A1 (de) * | 1996-04-19 | 1997-10-23 | Beiersdorf Ag | Verwendung von Glucosiden und Ferulasäure als antiirritativer Wirkstoff in kosmetischen und topischen dermatologischen Zubereitungen |
| US6696407B1 (en) | 1997-03-21 | 2004-02-24 | The Regents Of The University Of California | Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF |
| AU6473898A (en) * | 1997-03-21 | 1998-10-20 | Regents Of The University Of California, The | Methods for modulating neurotrophic factor-associated activity using aldose reductase inhibitors |
| US6679584B2 (en) * | 1997-07-15 | 2004-01-20 | Silverbrook Research Pty Ltd. | High volume pagewidth printing |
| US8466109B2 (en) * | 1998-10-05 | 2013-06-18 | Laboratoires Expanscience | Cosmetic method for preventing and/or treating skin stretchmarks, and use in dermatology |
| AU1041800A (en) * | 1998-11-02 | 2000-05-22 | Ciba Specialty Chemicals Holding Inc. | Stabilisation of body-care and household products |
| FR2787996B1 (fr) * | 1998-12-30 | 2002-05-10 | Dior Christian Parfums | Composition cosmetique ou dermatologique contenant un actif stimulant la synthese de la proteine hsp 32 dans la peau et methode de traitement cosmetique |
| US20040228816A1 (en) * | 1998-12-30 | 2004-11-18 | Carine Nizard | Cosmetic or dermatological composition containing an active agent which stimulates synthesis of the protein HSP 32 in the skin |
| IT1317732B1 (it) * | 2000-01-20 | 2003-07-15 | Giuliani Spa | Composti ad attivita' antiossidante, composizioni utili qualiintegratori alimentari che li contengono e procedimento per |
| US6437004B1 (en) | 2000-04-06 | 2002-08-20 | Nicholas V. Perricone | Treatment of skin damage using olive oil polyphenols |
| EP1166765A3 (de) * | 2000-06-20 | 2002-05-02 | Laboratoires Serobiologiques | Verfahren zum Schutz der menschlichen Haut |
| US7713569B2 (en) * | 2000-09-01 | 2010-05-11 | Creagri, Inc. | Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof |
| JP3820218B2 (ja) * | 2000-09-01 | 2006-09-13 | クレアグリ, インコーポレイテッド | 植物水からヒドロキシチロソール富化組成物を得る方法 |
| EP1260212A1 (de) * | 2001-05-21 | 2002-11-27 | Cognis France S.A. | Kosmetische Mittel |
| JP2002363075A (ja) | 2001-06-05 | 2002-12-18 | Kao Corp | 高血圧症予防・治療剤 |
| WO2003068171A2 (en) * | 2002-02-13 | 2003-08-21 | Creagri, Inc. | Method and composition for treatment of inflammation and aids-associated neurological disorders |
| DE10215055A1 (de) * | 2002-04-03 | 2003-10-30 | Univ Schiller Jena | Verwendung von Kaffeesäureestern zur Herstellung von kosmetischen nutrazeutischen sowie pharmazeutischen Präparaten und Arzneimitteln |
| US6989162B2 (en) * | 2003-03-31 | 2006-01-24 | Council Of Scientific & Industrial Research | Hepatoprotective agent of plant origin and a process thereof |
| ATE376426T1 (de) * | 2003-03-31 | 2007-11-15 | Council Scient Ind Res | Isolierung des hepatoprotektiven wirkstoffes acteosid aus colerbrookea oppositifolia |
| US20060020029A1 (en) * | 2004-07-02 | 2006-01-26 | Shimasaki Craig D | Pharmaceutical compositions from ethnobotanicals |
| JP2008509224A (ja) * | 2004-08-09 | 2008-03-27 | クレアグリ, インコーポレイテッド | 炎症状態を治療するためのオリーブ組成物及び方法 |
| US9789149B2 (en) * | 2005-07-19 | 2017-10-17 | Creagri, Inc. | Vegetation water composition for treatment of inflammatory skin conditions |
| FR2892923B1 (fr) * | 2005-11-08 | 2009-01-16 | Engelhard Lyon Sa | Utilisatiion des derives de l'acide para-coumarique ou para- hydroxycinnamique dans des compositions cosmetiques ou dermatologiques. |
| WO2008083389A1 (en) * | 2006-12-29 | 2008-07-10 | Moleculin, L.L.C. | Methods of treating skin disorders with caffeic acid analogs |
| WO2008093678A1 (ja) * | 2007-01-29 | 2008-08-07 | Oryza Oil & Fat Chemical Co., Ltd. | ヒアルロニダーゼ阻害剤 |
| JP2009263279A (ja) * | 2008-04-25 | 2009-11-12 | Oriza Yuka Kk | エラスターゼ阻害剤 |
| US8450337B2 (en) * | 2008-09-30 | 2013-05-28 | Moleculin, Llc | Methods of treating skin disorders with caffeic acid analogs |
| WO2012143017A1 (en) | 2011-04-17 | 2012-10-26 | El-Sawy Mohamed Fakhr El-Din | The use of orobancheace extract for the treatment of hepatitis c virus and nonalcoholic fatty liver disease |
| GB201705403D0 (en) * | 2017-04-04 | 2017-05-17 | Givaudan Sa | Improvements in or relating to organic compounds |
| CN109776633B (zh) * | 2019-03-18 | 2020-08-04 | 暨南大学 | 一种苯丙素类化合物及其制备方法与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2314725A1 (fr) * | 1975-03-07 | 1977-01-14 | Screen | Procede pour la preparation d'heterosides de dihydroxyphenylalcanol et medicaments contenant de tels heterosides |
| FR2302745A1 (fr) * | 1975-03-07 | 1976-10-01 | Screen | Esters heterosidiques d'acide cafeique, leurs procedes de preparation e |
| FR2652086B1 (fr) * | 1989-09-20 | 1993-05-21 | Andary Claude | Compose nouveau d'origine vegetale, derive de l'acide cafeique, l'oraposide; composition a usage therapeutique et composition dermato-cosmetique le contenant. |
-
1991
- 1991-03-21 JP JP50647591A patent/JP3147900B2/ja not_active Expired - Fee Related
- 1991-03-21 DE DE69110136T patent/DE69110136T2/de not_active Expired - Fee Related
- 1991-03-21 US US08/119,172 patent/US5719129A/en not_active Expired - Lifetime
- 1991-03-21 ES ES91907075T patent/ES2075437T3/es not_active Expired - Lifetime
- 1991-03-21 KR KR1019930702831A patent/KR100194830B1/ko not_active Expired - Fee Related
- 1991-03-21 WO PCT/FR1991/000229 patent/WO1992016544A1/fr not_active Ceased
- 1991-03-21 AT AT91907075T patent/ATE123287T1/de active
- 1991-03-21 CA CA002102689A patent/CA2102689A1/fr not_active Abandoned
- 1991-03-21 EP EP91907075A patent/EP0576420B1/fr not_active Expired - Lifetime
- 1991-03-21 AU AU75850/91A patent/AU670742B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0576420A1 (fr) | 1994-01-05 |
| AU7585091A (en) | 1992-10-21 |
| JP3147900B2 (ja) | 2001-03-19 |
| US5719129A (en) | 1998-02-17 |
| CA2102689A1 (fr) | 1992-09-22 |
| KR100194830B1 (ko) | 1999-06-15 |
| ATE123287T1 (de) | 1995-06-15 |
| DE69110136T2 (de) | 1996-01-11 |
| DE69110136D1 (de) | 1995-07-06 |
| JPH06508601A (ja) | 1994-09-29 |
| WO1992016544A1 (fr) | 1992-10-01 |
| EP0576420B1 (fr) | 1995-05-31 |
| AU670742B2 (en) | 1996-08-01 |
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