ES2075835T3 - Correccion con arn de doble cadena de una insuficiencia en la arnasa l. - Google Patents

Correccion con arn de doble cadena de una insuficiencia en la arnasa l.

Info

Publication number
ES2075835T3
ES2075835T3 ES88306419T ES88306419T ES2075835T3 ES 2075835 T3 ES2075835 T3 ES 2075835T3 ES 88306419 T ES88306419 T ES 88306419T ES 88306419 T ES88306419 T ES 88306419T ES 2075835 T3 ES2075835 T3 ES 2075835T3
Authority
ES
Spain
Prior art keywords
arnasa
insufficiency
correction
double chain
chain rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88306419T
Other languages
English (en)
Inventor
William A Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEM Pharmaceuticals Corp
Original Assignee
HEM Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEM Pharmaceuticals Corp filed Critical HEM Pharmaceuticals Corp
Application granted granted Critical
Publication of ES2075835T3 publication Critical patent/ES2075835T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/922—Ribonucleases (RNAses); Deoxyribonucleases (DNAses)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL USO DE UN DNA DE DOBLE HEBRA PARA LA FABRICACION DE UN MEDICAMENTO PARA CORREGIR EL SISTEMA DE DEFENSA NATURAL POR 2'',5''-OLIGOADENILATO SINTETASA (2'',5''A)/RNA-ASA L DESARREGLADO EN UN INDIVIDUO
ES88306419T 1987-07-17 1988-07-13 Correccion con arn de doble cadena de una insuficiencia en la arnasa l. Expired - Lifetime ES2075835T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7464987A 1987-07-17 1987-07-17

Publications (1)

Publication Number Publication Date
ES2075835T3 true ES2075835T3 (es) 1995-10-16

Family

ID=22120800

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88306419T Expired - Lifetime ES2075835T3 (es) 1987-07-17 1988-07-13 Correccion con arn de doble cadena de una insuficiencia en la arnasa l.

Country Status (18)

Country Link
EP (2) EP0525917A3 (es)
JP (1) JPH01104015A (es)
KR (1) KR970007903B1 (es)
CN (1) CN1032741A (es)
AT (1) ATE123222T1 (es)
AU (3) AU1820388A (es)
CA (1) CA1331345C (es)
DE (1) DE3853898T2 (es)
DK (1) DK363088A (es)
ES (1) ES2075835T3 (es)
FI (1) FI883351A7 (es)
GR (1) GR3017271T3 (es)
IE (1) IE75896B1 (es)
IL (1) IL86865A (es)
NO (1) NO882854L (es)
PT (1) PT87997B (es)
RU (1) RU1838419C (es)
ZA (1) ZA885095B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE72103B1 (en) * 1987-08-12 1997-03-12 Hem Res Inc Promotion of host defense by systemic dsRNA treatment
EP0306347B1 (en) * 1987-09-04 1995-05-10 Hem Pharmaceuticals Corp. Diagnosis of double-stranded RNA deficiency states
NO883868L (no) * 1987-09-04 1989-03-06 Hem Res Inc Fremgangsmaate for diagnostisering av dsrna-mangeltilstander, samt fremgangsmaate for fremstilling av preparater for diagnostisering og behandling av slike tilstander.
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
DE68914201T2 (de) * 1988-07-07 1994-07-14 Hem Pharma Corp Diagnose und Behandlung chronischer Ermüdungserscheinungen.
BR9007741A (pt) * 1989-10-11 1992-08-11 Hem Res Inc Protecao contra estados de choque subsequentes a lesoes por rnas de duplo filamento
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
CA2113573A1 (en) * 1991-07-16 1993-02-04 William Carter Modulation and diagnosis of cytokine dysfunctions
US5985565A (en) * 1996-10-09 1999-11-16 Temple University-Of The Commonwealth System Of Higher Education Chronic fatigue syndrome diagnosis
TW524693B (en) * 1997-10-16 2003-03-21 Nippon Shinyaku Co Ltd Cancer cell nuclease activator
US6207366B1 (en) 1999-04-14 2001-03-27 Temple University- Of The Commonwealth System Of Higher Education Chronic fatigue syndrome diagnosis
CN100358534C (zh) * 2005-11-21 2008-01-02 北京百林康源生物技术有限责任公司 错位双链寡核苷酸在制备治疗禽流感病毒感染的药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024222A (en) 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
EP0113162B1 (en) * 1982-09-16 1989-07-19 Hem Research, Inc. Anti-proliferative action of dsnras on tumor cells
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
ZA885095B (en) 1989-07-26
EP0299745B1 (en) 1995-05-31
IE881895L (en) 1989-01-17
PT87997B (pt) 1995-03-01
AU1619092A (en) 1992-08-13
DK363088D0 (da) 1988-06-30
KR970007903B1 (ko) 1997-05-17
GR3017271T3 (en) 1995-11-30
DE3853898T2 (de) 1996-02-29
RU1838419C (ru) 1993-08-30
CN1032741A (zh) 1989-05-10
NO882854L (no) 1989-01-18
KR890002420A (ko) 1989-04-10
AU1502695A (en) 1995-07-06
EP0299745A2 (en) 1989-01-18
CA1331345C (en) 1994-08-09
IL86865A0 (en) 1988-11-30
FI883351L (fi) 1989-01-18
EP0525917A3 (en) 1993-02-24
IL86865A (en) 1993-06-10
JPH01104015A (ja) 1989-04-21
ATE123222T1 (de) 1995-06-15
AU1820388A (en) 1989-01-19
NO882854D0 (no) 1988-06-28
IE75896B1 (en) 1997-09-24
DE3853898D1 (de) 1995-07-06
PT87997A (pt) 1989-06-30
EP0299745A3 (en) 1989-12-06
DK363088A (da) 1989-01-18
EP0525917A2 (en) 1993-02-03
FI883351A7 (fi) 1989-01-18
FI883351A0 (fi) 1988-07-14

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