ES2076181T3 - Sintesis de intermediarios utiles en la preparacion de nojirimicina y compuestos relacionados. - Google Patents
Sintesis de intermediarios utiles en la preparacion de nojirimicina y compuestos relacionados.Info
- Publication number
- ES2076181T3 ES2076181T3 ES89117039T ES89117039T ES2076181T3 ES 2076181 T3 ES2076181 T3 ES 2076181T3 ES 89117039 T ES89117039 T ES 89117039T ES 89117039 T ES89117039 T ES 89117039T ES 2076181 T3 ES2076181 T3 ES 2076181T3
- Authority
- ES
- Spain
- Prior art keywords
- nojirimycin
- synthesis
- preparation
- related compounds
- useful intermediaries
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- BGMYHTUCJVZIRP-UHFFFAOYSA-N Nojirimycin Natural products OCC1NC(O)C(O)C(O)C1O BGMYHTUCJVZIRP-UHFFFAOYSA-N 0.000 title abstract 2
- BGMYHTUCJVZIRP-GASJEMHNSA-N nojirimycin Chemical compound OC[C@H]1NC(O)[C@H](O)[C@@H](O)[C@@H]1O BGMYHTUCJVZIRP-GASJEMHNSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- CLVUFWXGNIFGNC-QTSLKERKSA-N (2r,3s,5r,6r)-2,6-bis(hydroxymethyl)piperidine-3,4,5-triol Chemical compound OC[C@H]1N[C@H](CO)[C@H](O)C(O)[C@@H]1O CLVUFWXGNIFGNC-QTSLKERKSA-N 0.000 abstract 1
- LXBIFEVIBLOUGU-UHFFFAOYSA-N Deoxymannojirimycin Natural products OCC1NCC(O)C(O)C1O LXBIFEVIBLOUGU-UHFFFAOYSA-N 0.000 abstract 1
- LXBIFEVIBLOUGU-JGWLITMVSA-N duvoglustat Chemical compound OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O LXBIFEVIBLOUGU-JGWLITMVSA-N 0.000 abstract 1
- 229950002441 glucurolactone Drugs 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Abstract
5 - AMINO - 5 - DEOXI - 1,2 - 0 - ISOPROPILIDENO - (ALFA) - D - GLUCOFURANOSO ES CONVENIENTEMENTE PREPARADO POR UNA REDUCCION HIBRIDA DE 5 - ACIDO - 5 - DEOXI - 1 - 2 - 0 - ISOPROPILIDENO - (ALFA) - D - GLUCORONOLACTONA Y PUEDE SER CONVERTIDA EN NOJIRIMICINA DIOXINOJIRIMICINA O HOMONOJIRIMICINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/245,848 US4908439A (en) | 1988-09-16 | 1988-09-16 | Synthesis of intermediate useful in the preparation of nojirimycin and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2076181T3 true ES2076181T3 (es) | 1995-11-01 |
Family
ID=22928336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89117039T Expired - Lifetime ES2076181T3 (es) | 1988-09-16 | 1989-09-14 | Sintesis de intermediarios utiles en la preparacion de nojirimicina y compuestos relacionados. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4908439A (es) |
| EP (1) | EP0359263B1 (es) |
| JP (1) | JP2787344B2 (es) |
| KR (1) | KR0135284B1 (es) |
| AT (1) | ATE124413T1 (es) |
| CA (1) | CA1323626C (es) |
| DE (1) | DE68923235T2 (es) |
| DK (1) | DK170751B1 (es) |
| ES (1) | ES2076181T3 (es) |
| HU (1) | HU202545B (es) |
| IE (1) | IE67558B1 (es) |
| IL (1) | IL91612A (es) |
| ZA (1) | ZA896920B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5227479A (en) * | 1989-12-20 | 1993-07-13 | Merrell Dow Pharmaceuticals Inc. | Process for the preparation of nojirimycin and related compounds |
| US6462197B2 (en) | 2000-03-31 | 2002-10-08 | Board Of Trustees Of Michigan State University | Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines |
| WO2010004269A2 (en) * | 2008-07-10 | 2010-01-14 | Dextra Laboratories Limited | Stereospecific synthesis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634765A (en) * | 1984-12-18 | 1987-01-06 | Merrell Dow Pharmaceuticals Inc. | Homodisaccharide hypoglycemic agents |
| DE3628486A1 (de) * | 1986-08-22 | 1988-02-25 | Bayer Ag | Piperidinderivate |
-
1988
- 1988-09-16 US US07/245,848 patent/US4908439A/en not_active Expired - Lifetime
-
1989
- 1989-09-11 ZA ZA896920A patent/ZA896920B/xx unknown
- 1989-09-12 KR KR1019890013193A patent/KR0135284B1/ko not_active Expired - Lifetime
- 1989-09-12 IL IL9161289A patent/IL91612A/en not_active IP Right Cessation
- 1989-09-14 EP EP89117039A patent/EP0359263B1/en not_active Expired - Lifetime
- 1989-09-14 JP JP1237403A patent/JP2787344B2/ja not_active Expired - Lifetime
- 1989-09-14 DE DE68923235T patent/DE68923235T2/de not_active Expired - Lifetime
- 1989-09-14 ES ES89117039T patent/ES2076181T3/es not_active Expired - Lifetime
- 1989-09-14 AT AT89117039T patent/ATE124413T1/de not_active IP Right Cessation
- 1989-09-15 HU HU894850A patent/HU202545B/hu unknown
- 1989-09-15 IE IE296189A patent/IE67558B1/en not_active IP Right Cessation
- 1989-09-15 DK DK454989A patent/DK170751B1/da not_active IP Right Cessation
- 1989-09-18 CA CA000611805A patent/CA1323626C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2787344B2 (ja) | 1998-08-13 |
| KR0135284B1 (ko) | 1998-04-23 |
| DK170751B1 (da) | 1996-01-08 |
| US4908439A (en) | 1990-03-13 |
| EP0359263B1 (en) | 1995-06-28 |
| EP0359263A2 (en) | 1990-03-21 |
| DE68923235T2 (de) | 1995-11-09 |
| ZA896920B (en) | 1990-06-27 |
| IE892961L (en) | 1990-03-16 |
| IE67558B1 (en) | 1996-04-17 |
| HU202545B (en) | 1991-03-28 |
| ATE124413T1 (de) | 1995-07-15 |
| EP0359263A3 (en) | 1990-10-24 |
| IL91612A0 (en) | 1990-04-29 |
| DE68923235D1 (de) | 1995-08-03 |
| KR900004755A (ko) | 1990-04-12 |
| DK454989A (da) | 1990-03-17 |
| IL91612A (en) | 1994-04-12 |
| DK454989D0 (da) | 1989-09-15 |
| HUT51280A (en) | 1990-04-28 |
| JPH02121999A (ja) | 1990-05-09 |
| CA1323626C (en) | 1993-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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