ES2076865B1 - Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat). - Google Patents

Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat).

Info

Publication number
ES2076865B1
ES2076865B1 ES9301508A ES9301508A ES2076865B1 ES 2076865 B1 ES2076865 B1 ES 2076865B1 ES 9301508 A ES9301508 A ES 9301508A ES 9301508 A ES9301508 A ES 9301508A ES 2076865 B1 ES2076865 B1 ES 2076865B1
Authority
ES
Spain
Prior art keywords
acil
acat
coenzyme
cholesterol
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9301508A
Other languages
English (en)
Other versions
ES2076865A1 (es
Inventor
Ernest S Hamanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Priority to ES9301508A priority Critical patent/ES2076865B1/es
Publication of ES2076865A1 publication Critical patent/ES2076865A1/es
Application granted granted Critical
Publication of ES2076865B1 publication Critical patent/ES2076865B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

UN COMPUESTO DE FORMULA I, SUS SALES FARMACEUTICAMENTE ACEPTABLES, EN DONDE Q, R17, R18 Y R1 SON COMO HAN QUEDADO DEFINIDOS EN LA MEMORIA. LOS COMPUESTOS DE FORMULA I SON INHIBIDORES DE LA ACIL-COENZIMA A: COLESTEROL ACIL-TRANSFERASA (ACAT) Y SON UTILES COMO AGENTES HIPOLIPIDEMICOS Y ANTIARTERIOSCLEROSIS.
ES9301508A 1993-07-05 1993-07-05 Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat). Expired - Fee Related ES2076865B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9301508A ES2076865B1 (es) 1993-07-05 1993-07-05 Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat).

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9301508A ES2076865B1 (es) 1993-07-05 1993-07-05 Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat).

Publications (2)

Publication Number Publication Date
ES2076865A1 ES2076865A1 (es) 1995-11-01
ES2076865B1 true ES2076865B1 (es) 1996-08-01

Family

ID=8282452

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9301508A Expired - Fee Related ES2076865B1 (es) 1993-07-05 1993-07-05 Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat).

Country Status (1)

Country Link
ES (1) ES2076865B1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT93158A (pt) * 1989-02-17 1990-08-31 Warner Lambert Co Processo para a preparacao de compostos de ureia trissubstituidos e de composicoes farmaceuticas que os contem
AU632809B2 (en) * 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
AU7440691A (en) * 1990-03-12 1991-10-10 Yamanouchi Pharmaceutical Co., Ltd. Monourea derivative and its salt
US5668136A (en) * 1990-09-25 1997-09-16 Eisai Co., Ltd. Trisubstituted benzene derivatives, composition and methods of treatment
IL101785A0 (en) * 1991-05-10 1992-12-30 Fujisawa Pharmaceutical Co Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
RU94046149A (ru) * 1992-05-28 1996-11-27 Пфайзер Инк. (US) Новые n-арил и n-гетероарил производные мочевины как ингибиторы ацил кофермента а:холестерин ацил трансферазы (асат) фармацевтическая композиция, способ ингибирования (асат)

Also Published As

Publication number Publication date
ES2076865A1 (es) 1995-11-01

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