ES2078543T3 - Secuencia nucleotidica que regula la iniciacion de la transcripcion. - Google Patents

Secuencia nucleotidica que regula la iniciacion de la transcripcion.

Info

Publication number
ES2078543T3
ES2078543T3 ES91916291T ES91916291T ES2078543T3 ES 2078543 T3 ES2078543 T3 ES 2078543T3 ES 91916291 T ES91916291 T ES 91916291T ES 91916291 T ES91916291 T ES 91916291T ES 2078543 T3 ES2078543 T3 ES 2078543T3
Authority
ES
Spain
Prior art keywords
initiation
sequence
transcription
promoter
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91916291T
Other languages
English (en)
Inventor
Philippe Mazodier
Gerard Guglielmi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur filed Critical Institut Pasteur
Application granted granted Critical
Publication of ES2078543T3 publication Critical patent/ES2078543T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UNA SECUENCIA NUCLEOTIDICA RECOMBINANTE CARACTERIZADA EN QUE COMPRENDE: UNA SECUENCIA REGULADORA DE LA INICIACION DE TRANSCRIPCION, COMPRENDIENDO ESTA SECUENCIA REGULADORA UN PROMOTOR EN ASOCIACION CON LA UNIDAD DE CADENA GCACTC 9N GAGTGC, EN LA QUE "N" SIGNIFICA UNA CUALQUIERA DE LAS 4 BASES TIMINA, GUANINA, ADENINA Y CITOSINA; CODIFICADO UNA SECUENCIA UN POLIPEPTIDO, LLAMADO "POLIPEPTIDO HETEROLOGO", DISTINTA DE LA NATURALMENTE ASOCIADA CON DICHO PROMOTOR; ESTANDO LA SECUENCIA CODIFICANTE POSICIONADA CORRIENTE ABAJO DE DICHA SECUENCIA REGULADORA DE LA INICIACION DE TRANSCRIPCION, EN UN LUGAR QUE, EN CONDICIONES APROPIADAS, PERMITIRIA LA EXPRESION DEL POLIPEPTIDO BAJO EL CONTROL DE DICHO PROMOTOR.
ES91916291T 1990-09-10 1991-09-03 Secuencia nucleotidica que regula la iniciacion de la transcripcion. Expired - Lifetime ES2078543T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9011186A FR2666588B1 (fr) 1990-09-10 1990-09-10 Sequence nucleotidique regulatrice de l'initiation de transcription.

Publications (1)

Publication Number Publication Date
ES2078543T3 true ES2078543T3 (es) 1995-12-16

Family

ID=9400203

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91916291T Expired - Lifetime ES2078543T3 (es) 1990-09-10 1991-09-03 Secuencia nucleotidica que regula la iniciacion de la transcripcion.

Country Status (15)

Country Link
US (2) US5858773A (es)
EP (1) EP0548175B1 (es)
JP (1) JPH05506581A (es)
KR (1) KR100219344B1 (es)
CN (1) CN1055499C (es)
AT (1) ATE127522T1 (es)
CA (1) CA2090010A1 (es)
DE (1) DE69112834T2 (es)
DK (1) DK0548175T3 (es)
ES (1) ES2078543T3 (es)
FR (1) FR2666588B1 (es)
GR (1) GR3017913T3 (es)
HU (1) HU214829B (es)
IL (2) IL99439A (es)
WO (1) WO1992004452A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0521220A1 (en) * 1991-06-14 1993-01-07 Institut Pasteur Recombinant immunogenic actinomycetale
US5850479A (en) * 1992-11-13 1998-12-15 The Johns Hopkins University Optical feature extraction apparatus and encoding method for detection of DNA sequences
US6258359B1 (en) * 1993-05-19 2001-07-10 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
US6822084B1 (en) * 1999-06-25 2004-11-23 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins
JP4161487B2 (ja) * 1999-11-01 2008-10-08 ソニー株式会社 データ復号装置及び方法
RU2225442C2 (ru) 2001-02-22 2004-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Рекомбинантная днк для контроля экспрессии, способ контроля экспрессии целевого гена, способ получения целевого вещества
GB0205647D0 (en) * 2002-03-11 2002-04-24 Danisco Cultor Niebull Gmbh Method of improving food fermentation procedures
GB0216414D0 (en) * 2002-07-15 2002-08-21 Novartis Ag Organic compounds
GB0303507D0 (en) * 2003-02-14 2003-03-19 Novartis Ag Organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797359A (en) * 1983-05-10 1989-01-10 Board Of Regents, The University Of Texas System Heat shock regulated production of selected and fused proteins in yeast
US4745056A (en) * 1984-10-23 1988-05-17 Biotechnica International, Inc. Streptomyces secretion vector
CA1295567C (en) * 1988-07-25 1992-02-11 Lawrence T. Malek Expression system for the secretion of bioactive human granulocyte, macrophage-colony stimulating factor (gm-csf) and other heterologous proteins from streptomyces
JPH0754404B2 (ja) * 1986-04-16 1995-06-07 富士写真フイルム株式会社 カラ−画像形成方法

Also Published As

Publication number Publication date
CA2090010A1 (fr) 1992-03-11
HU9300653D0 (en) 1993-05-28
JPH05506581A (ja) 1993-09-30
WO1992004452A1 (fr) 1992-03-19
DE69112834T2 (de) 1996-04-04
US6153404A (en) 2000-11-28
FR2666588A1 (fr) 1992-03-13
IL128155A0 (en) 1999-11-30
KR100219344B1 (ko) 1999-10-01
HU214829B (hu) 1998-06-29
DK0548175T3 (da) 1995-11-13
CN1055499C (zh) 2000-08-16
EP0548175A1 (fr) 1993-06-30
CN1059935A (zh) 1992-04-01
US5858773A (en) 1999-01-12
EP0548175B1 (fr) 1995-09-06
IL99439A0 (en) 1992-08-18
KR930702531A (ko) 1993-09-09
IL99439A (en) 1999-11-30
FR2666588B1 (fr) 1994-02-11
GR3017913T3 (en) 1996-01-31
HUT64396A (en) 1993-12-28
ATE127522T1 (de) 1995-09-15
DE69112834D1 (de) 1995-10-12

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