ES2080549T3 - Medicamentos a base de derivados de polihidroximetileno, procedimiento para su preparacion y empleo. - Google Patents

Medicamentos a base de derivados de polihidroximetileno, procedimiento para su preparacion y empleo.

Info

Publication number
ES2080549T3
ES2080549T3 ES93104655T ES93104655T ES2080549T3 ES 2080549 T3 ES2080549 T3 ES 2080549T3 ES 93104655 T ES93104655 T ES 93104655T ES 93104655 T ES93104655 T ES 93104655T ES 2080549 T3 ES2080549 T3 ES 2080549T3
Authority
ES
Spain
Prior art keywords
polyhydroxymethylene
derivatives
procedure
preparation
medicines based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93104655T
Other languages
English (en)
Inventor
Kurt Dr Kesseler
Rudolf Schmidtberger
Stefan Dr Muellner
Ernold Dr Dr Granzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2080549T3 publication Critical patent/ES2080549T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

LA INVENCION CONCIERNE A UN MEDICAMENTO, CONTENIENDO UN PORCENTAJE ACTIVO DE UN POLIHIDROXIMETILENO, CON ALCOHOLES INJERTADOS OXIETILADOS, Y/O ACIDOS CARBOXILICOS OXIETILADOS. EL MEDICAMENTO ES UTILIZADO PARA EL TRATAMIENTO DE ANEMIAS DISLIPOPROTEINICAS.
ES93104655T 1992-03-28 1993-03-22 Medicamentos a base de derivados de polihidroximetileno, procedimiento para su preparacion y empleo. Expired - Lifetime ES2080549T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4210220 1992-03-28

Publications (1)

Publication Number Publication Date
ES2080549T3 true ES2080549T3 (es) 1996-02-01

Family

ID=6455312

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93104655T Expired - Lifetime ES2080549T3 (es) 1992-03-28 1993-03-22 Medicamentos a base de derivados de polihidroximetileno, procedimiento para su preparacion y empleo.

Country Status (12)

Country Link
US (1) US5401498A (es)
EP (1) EP0563731B1 (es)
JP (1) JPH0640925A (es)
KR (1) KR930019220A (es)
AT (1) ATE130193T1 (es)
AU (1) AU666173B2 (es)
DE (1) DE59300925D1 (es)
DK (1) DK0563731T3 (es)
ES (1) ES2080549T3 (es)
FI (1) FI931336A7 (es)
GR (1) GR3018185T3 (es)
NO (1) NO931133L (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6107494A (en) * 1994-09-13 2000-08-22 G.D. Searle And Company Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US5994391A (en) * 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6299868B1 (en) 1999-07-14 2001-10-09 Geltex Pharmaceuticals, Inc. Fat-binding polymers
US7048917B1 (en) 1998-01-09 2006-05-23 Genzyme Corporation Fat-binding polymers
US6267952B1 (en) 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
US6264937B1 (en) 1998-01-09 2001-07-24 Geltex Pharmaceuticals, Inc. Fat-binding polymers
AU3304499A (en) * 1998-02-20 1999-09-06 City Of Hope Association of the serotonin transport (htt) gene with cardiovascular disease and longevity
EP1342475A1 (en) 1998-12-23 2003-09-10 G.D. Searle LLC. Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
DK1140185T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferhæmmere og galdesyre kompleksdannende forbindelser til hjertekar indikationer
EP1140186B1 (en) 1998-12-23 2003-06-04 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
AU2157400A (en) 1998-12-23 2000-07-31 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
DK1140184T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferproteinhæmmere og nikotinsyrederivater til hjertekar indikationer
PT1140190E (pt) 1998-12-23 2003-02-28 Searle Llc Combinacoes de inibidores do transporte ileal dos acidos biliares e agentes sequestrantes dos acidos biliares usadas para problemas cardiovasculares
MXPA01006472A (es) 1998-12-23 2004-03-10 Searle Llc Combinaciones de inhibidores de transporte de acido biliar ileal y derivados de acido fibrico para indicaciones cardiovasculares.
EP1286984A2 (en) 2000-03-10 2003-03-05 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US7049345B2 (en) * 2001-06-29 2006-05-23 Genzyme Corporation Fat-binding polymers
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US6740663B2 (en) 2001-11-02 2004-05-25 G.D. Searle, Llc Mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
AU2003207431A1 (en) 2002-01-17 2003-09-02 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
CA2557999C (en) * 2004-03-30 2013-11-12 Ilypsa, Inc. Methods and compositions for treatment of ion imbalances
CN106478948B (zh) * 2010-02-24 2019-05-07 瑞立普萨公司 用作胆汁酸螯合剂的聚咪唑

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
US4027009A (en) * 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol
DE2556759A1 (de) * 1975-12-17 1977-06-30 Hoechst Ag Verfahren zur herstellung von polymeren des vinylencarbonats
DE3330648C2 (de) * 1983-08-25 1986-11-20 Behringwerke Ag, 3550 Marburg Verfahren zum Abtrennen von Lipoproteinen mittels derivatisiertem Polyhydroxymethylen
DE3413904A1 (de) * 1984-04-13 1985-10-24 Hoechst Ag, 6230 Frankfurt Polymerisate auf basis von polyvinylencarbonat und/oder polyhydroxymethylen, verfahren zu ihrer herstellung und ihre anwendung
DE68909982T2 (de) * 1988-03-24 1994-02-10 Taisho Pharma Co Ltd Cholesterolvermindernde Wirkstoffe.
DE3901527A1 (de) * 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
GB8911719D0 (en) * 1989-05-22 1989-07-05 Smith Kline French Lab Compounds
CA2040996A1 (en) * 1990-05-02 1991-11-03 Robert L. Albright Composition and method for controlling cholesterol

Also Published As

Publication number Publication date
EP0563731A1 (de) 1993-10-06
AU3544693A (en) 1993-09-30
US5401498A (en) 1995-03-28
KR930019220A (ko) 1993-10-18
NO931133D0 (no) 1993-03-26
GR3018185T3 (en) 1996-02-29
FI931336A0 (fi) 1993-03-25
ATE130193T1 (de) 1995-12-15
EP0563731B1 (de) 1995-11-15
DE59300925D1 (de) 1995-12-21
JPH0640925A (ja) 1994-02-15
DK0563731T3 (da) 1996-03-18
FI931336L (fi) 1993-09-29
FI931336A7 (fi) 1993-09-29
AU666173B2 (en) 1996-02-01
NO931133L (no) 1993-09-29

Similar Documents

Publication Publication Date Title
DK273489D0 (da) Terapeutisk produkt
MA23608A1 (fr) Forme de dosage ii d'unite multiple en comprime
PT83872A (de) Arzneimittel
DK136186D0 (da) Laegemiddelbaerer
ES2136105T3 (es) Preparacion farmaceutica y/o cosmetica.
ATE74519T1 (de) Waessrige loesung von fettloeslichen wirkstoffen.
ATE211907T1 (de) Osmotisches arzneimittelfreisetzungssystem
MX9300014A (es) Nuevos derivados de 1,2,4-triaminobenceno y procedimiento para su elaboracion.
DE69327432D1 (de) Heilmittel für wunden und hämorrhoiden
DE3880667D1 (de) Ampulle zur gesteuerten verabreichung eines heilmittels.
ES2058988T3 (es) Preparacion de medicamentos para el tratamiento sistemico de peces ornamentales y utiles.
AR059965A2 (es) Uso de 8,9-dehidroestrona para la preparacion de un medicamento antioxidante
DK561589A (da) Flydende oralt farmaceutisk praeparat
DE69104608D1 (de) Pharmazeutische Zubereitungen, Clavulansäure enthaltend, für die Behandlung der Periodontitis.
ES2118248T3 (es) Esteres y amidas de 9-cloro-prostaglandina y su empleo para preparar medicamentos.
DE68921180D1 (de) Apparat für die Verabreichung von Medikamenten für die Veterinärmedizin.
ES2184121T3 (es) Formulacion para el tratamiento y/o profilaxis de la demencia.
NL7903434A (nl) Derivaten van benzoylfenoxyalkaancarbonzuren met anti- lipemische en anticholesterolemische werking, alsmede farmaceutische preparaten die zo'n verbinding bevatten.
NL193316B (nl) Onverzadigde cycloalifatische verbindingen, en cosmetische en farmaceutische preparaten, die deze onverzadigde cycloalifatische verbindingen bevatten.
ATE87211T1 (de) Heilpflanzengemisch fuer die behandlung von depressionen.
DK67493D0 (da) Biologisk aktivt produkt og fremgangsmaade til fremstilling deraf samt farmaceutiske og kosmetiske praeparater indeholdende produktet
IT8720708A0 (it) Sistema terapeutico per la cessione controllata di farmaci.
MX9203800A (es) Sistemas de droga de baja toxicidad-lipido.
TH13992A (th) การใช้ไลโซไซม์ ไดเมอร์ แบบใหม่และสารผสมที่มีไลโซไซม์ไดเมอร์
IT1255678B (it) Composizioni farmaceutiche per la somministrazione di paratormone, suoi frammenti biologicamente attivi o peptidi correlati per via rettale.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 563731

Country of ref document: ES