ES2082220T3 - Preparacion de acidos acil-aminometano-fosfonicos y de acidos acil-aminometil-fosfinicos. - Google Patents
Preparacion de acidos acil-aminometano-fosfonicos y de acidos acil-aminometil-fosfinicos.Info
- Publication number
- ES2082220T3 ES2082220T3 ES91914144T ES91914144T ES2082220T3 ES 2082220 T3 ES2082220 T3 ES 2082220T3 ES 91914144 T ES91914144 T ES 91914144T ES 91914144 T ES91914144 T ES 91914144T ES 2082220 T3 ES2082220 T3 ES 2082220T3
- Authority
- ES
- Spain
- Prior art keywords
- acids
- acil
- formula
- preparation
- aminomethane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002253 acid Substances 0.000 title abstract 6
- 150000007513 acids Chemical class 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 5
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
EL ACIDO ACILAMINO METANO FOSFONICO Y LOS ACIDOS ACILAMINO METANO FOSFINICOS DE LA FORMULA (I): R2-CO-NH-CH2-P(O)(OH)R1, EN LA QUE R1 SIGNIFICA HIDROXI, ALQUILO C1-C4 O FENILO Y R2 SIGNIFICA H, ALQUILO C1-C6, BENCILO O FENILO, QUE ESTA INSUSTITUIDO O SUSTITUIDO POR UNO O MAS RESIDUOS ESCOGIDOS DEL GRUPO COMPUESTO DE ALQUILO C1-C4, ALCOXI C1-C4 Y HALOGENO, SON PRODUCTOS INTERMEDIOS UTILES EN LA PREPARACION DE COMPUESTOS ACTIVOS BIOLOGICAMENTE. PUEDEN SER PREPARADOS POR REACCION DE UN COMPUESTO DE LA FORMULA (II): R2-CO-NH-CH2-OH CON COMPUESTOS DE LA FORMULA (III): H-P(O)(OH)R1, EN PRESENCIA DE POR LO MENOS CANTIDADES EQUIMOLARES DE ANHIDRIDO ACETICO REFERIDAS AL COMPUESTO DE LA FORMULA (II). LOS COMPUESTOS DE LA FORMULA (I) EN LA R1 NO ES HIDROXI SON NUEVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4026026A DE4026026A1 (de) | 1990-08-17 | 1990-08-17 | Acylaminomethyl-phosphinsaeuren und verfahren zur herstellung von acylaminomethanphosphonsaeuren und acylaminomethyl-phosphinsaeuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2082220T3 true ES2082220T3 (es) | 1996-03-16 |
Family
ID=6412398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91914144T Expired - Lifetime ES2082220T3 (es) | 1990-08-17 | 1991-08-07 | Preparacion de acidos acil-aminometano-fosfonicos y de acidos acil-aminometil-fosfinicos. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5432291A (es) |
| EP (1) | EP0543850B1 (es) |
| JP (1) | JP3236612B2 (es) |
| CN (1) | CN1028995C (es) |
| AT (1) | ATE131485T1 (es) |
| AU (1) | AU8310091A (es) |
| CA (1) | CA2089652C (es) |
| DE (2) | DE4026026A1 (es) |
| DK (1) | DK0543850T3 (es) |
| ES (1) | ES2082220T3 (es) |
| IE (1) | IE912919A1 (es) |
| IL (1) | IL99202A (es) |
| PT (1) | PT98699B (es) |
| WO (1) | WO1992003450A1 (es) |
| ZA (1) | ZA916503B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2168273T3 (es) * | 1992-04-23 | 2002-06-16 | Sloan Kettering Inst Cancer | Ligando para el receptor c-kit y metodos de uso del mismo. |
| JP3438228B2 (ja) | 1998-03-19 | 2003-08-18 | 松下電器産業株式会社 | アンテナ装置およびそれを用いた移動体通信機器 |
| RU2674021C9 (ru) | 2012-07-17 | 2019-01-24 | МОНСАНТО ТЕКНОЛОДЖИ ЭлЭлСи | Способ синтеза n-(фосфонометил)глицина |
| EP2875038A1 (en) | 2012-07-17 | 2015-05-27 | Straitmark Holding AG | Method for the synthesis of n-phosphonomethyliminodiacetic acid |
| RU2694047C2 (ru) | 2012-07-17 | 2019-07-09 | МОНСАНТО ТЕКНОЛОДЖИ ЭлЭлСи | Способ синтеза аминоалкиленфосфоновой кислоты |
| IN2015DN01081A (es) | 2012-07-17 | 2015-06-26 | Straitmark Holding Ag |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2328358A (en) | 1941-01-23 | 1943-08-31 | Du Pont | Organic compound and process for preparing the same |
| DE3824961A1 (de) | 1988-07-22 | 1990-01-25 | Basf Ag | Verfahren zur herstellung von bis(aminomethyl)-phosphinsaeure oder deren sauren oder basischen salzen |
| HU203360B (en) * | 1988-11-25 | 1991-07-29 | Monsanto Co | Process for producing n-acylamino methylphosphonates |
-
1990
- 1990-08-17 DE DE4026026A patent/DE4026026A1/de not_active Withdrawn
-
1991
- 1991-08-07 ES ES91914144T patent/ES2082220T3/es not_active Expired - Lifetime
- 1991-08-07 AT AT91914144T patent/ATE131485T1/de not_active IP Right Cessation
- 1991-08-07 DE DE59107093T patent/DE59107093D1/de not_active Expired - Fee Related
- 1991-08-07 CA CA002089652A patent/CA2089652C/en not_active Expired - Fee Related
- 1991-08-07 WO PCT/EP1991/001495 patent/WO1992003450A1/de not_active Ceased
- 1991-08-07 JP JP51316891A patent/JP3236612B2/ja not_active Expired - Fee Related
- 1991-08-07 DK DK91914144.0T patent/DK0543850T3/da active
- 1991-08-07 EP EP91914144A patent/EP0543850B1/de not_active Expired - Lifetime
- 1991-08-07 AU AU83100/91A patent/AU8310091A/en not_active Abandoned
- 1991-08-15 IL IL9920291A patent/IL99202A/en not_active IP Right Cessation
- 1991-08-16 CN CN91105717A patent/CN1028995C/zh not_active Expired - Fee Related
- 1991-08-16 PT PT98699A patent/PT98699B/pt not_active IP Right Cessation
- 1991-08-16 ZA ZA916503A patent/ZA916503B/xx unknown
- 1991-08-16 IE IE291991A patent/IE912919A1/en unknown
-
1993
- 1993-02-11 US US07/969,167 patent/US5432291A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU8310091A (en) | 1992-03-17 |
| EP0543850B1 (de) | 1995-12-13 |
| EP0543850A1 (de) | 1993-06-02 |
| JPH06501925A (ja) | 1994-03-03 |
| IE912919A1 (en) | 1992-02-26 |
| IL99202A0 (en) | 1992-07-15 |
| WO1992003450A1 (de) | 1992-03-05 |
| ZA916503B (en) | 1992-04-29 |
| DK0543850T3 (da) | 1996-03-11 |
| JP3236612B2 (ja) | 2001-12-10 |
| CA2089652C (en) | 2001-09-18 |
| CN1059147A (zh) | 1992-03-04 |
| CN1028995C (zh) | 1995-06-21 |
| CA2089652A1 (en) | 1992-02-18 |
| US5432291A (en) | 1995-07-11 |
| PT98699B (pt) | 1999-01-29 |
| IL99202A (en) | 1995-10-31 |
| DE4026026A1 (de) | 1992-02-20 |
| ATE131485T1 (de) | 1995-12-15 |
| DE59107093D1 (de) | 1996-01-25 |
| PT98699A (pt) | 1992-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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