ES2083371T3 - Procedimiento para la identificacion de arnm cortado y empalmado. - Google Patents

Procedimiento para la identificacion de arnm cortado y empalmado.

Info

Publication number
ES2083371T3
ES2083371T3 ES89120548T ES89120548T ES2083371T3 ES 2083371 T3 ES2083371 T3 ES 2083371T3 ES 89120548 T ES89120548 T ES 89120548T ES 89120548 T ES89120548 T ES 89120548T ES 2083371 T3 ES2083371 T3 ES 2083371T3
Authority
ES
Spain
Prior art keywords
arnm
spined
identification
procedure
cut
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89120548T
Other languages
English (en)
Inventor
Peter Dr Cerutti
Jeannette Dr Whitcomb
Jacob Dr Zijlstra
Villiers Ethel-Michelle Dr De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2083371T3 publication Critical patent/ES2083371T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

EL INVENTO SE REFIERE A LA COMPROBACION DIRECTA DE VIRUS DNA PAPILOMA HUMANO. LA REACCION EN CADENA A PARTIR DE POLIMERASA CORTAMENTE DESARROLLADA SE MODIFICA PARA MEJORAR SENSIBILIDAD Y ESPECIFICIDAD. MEDIANTE LA SELECCION DE OLIGONUCLEOSIDO PRIMARIOS Y TEMPERATURAS DE REACCION PUEDEN IDENTIFICARSE INDIVIDUALMENTE GENES HPV BAJO CELULAS DNA COMUNES Y AMPLIFICARSE, YA QUE ES POSIBLE UNA COMPROBACION NO ISOTOPICA. PERMITE EL EMPLEO DE TRANSCRIPCION REVERSIBLE LA AMPLIFICIACION PUNTUAL DE MRNA EMPALMADA Y LA MODIFICACION DE LESIONES.
ES89120548T 1988-11-11 1989-11-07 Procedimiento para la identificacion de arnm cortado y empalmado. Expired - Lifetime ES2083371T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3838269A DE3838269A1 (de) 1988-11-11 1988-11-11 Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen

Publications (1)

Publication Number Publication Date
ES2083371T3 true ES2083371T3 (es) 1996-04-16

Family

ID=6366963

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89120548T Expired - Lifetime ES2083371T3 (es) 1988-11-11 1989-11-07 Procedimiento para la identificacion de arnm cortado y empalmado.

Country Status (10)

Country Link
US (1) US5750334A (es)
EP (1) EP0373352B1 (es)
JP (1) JP3375623B2 (es)
AT (1) ATE133715T1 (es)
AU (1) AU627517B2 (es)
CA (1) CA2002776C (es)
DE (2) DE3838269A1 (es)
DK (1) DK175222B1 (es)
ES (1) ES2083371T3 (es)
FI (1) FI100474B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
AU6966991A (en) * 1989-12-01 1991-06-26 Gene-Trak Systems Detection of hpv transcripts
WO1991008313A1 (en) * 1989-12-04 1991-06-13 Isis Pharmaceuticals, Inc. Antisense oligonucleotide inhibition of papillomavirus
GB9015845D0 (en) * 1990-07-19 1990-09-05 Emery Vincent C Diagnostic method
CA2065719A1 (en) * 1991-04-30 1992-10-31 John B. Findlay Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
CA2139623A1 (en) * 1993-05-06 1994-11-24 Baxter Diagnostics Inc. Human papillomavirus detection assay
SG63589A1 (en) * 1993-05-14 1999-03-30 Johnson & Johnson Clin Diag Diagnostic compositions elements methods and test kits for amplification and detection of two or more dna's using primers having matched melting temperatures
DE4431174A1 (de) * 1994-09-01 1996-03-07 Deutsches Krebsforsch Nachweisverfahren für tumorspezifische mRNA
DE19506561C1 (de) * 1995-02-24 1996-10-10 Deutsches Krebsforsch Verfahren zur Früherkennung von HPV-assoziierten Karzinomen bzw. von hochgradigen, durch HPV-verursachten Dysplasien
US5882857A (en) * 1995-06-07 1999-03-16 Behringwerke Ag Internal positive controls for nucleic acid amplification
DE19526717A1 (de) * 1995-07-21 1997-01-23 Florian Dr Med Heirler Verfahren zur Diagnose des Zervixkarzinoms
WO1997018334A2 (en) * 1995-11-15 1997-05-22 Gen-Probe Incorporated Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits
JP2002541822A (ja) 1999-04-14 2002-12-10 エム ユー エス シー ファンデーション フォー リサーチ ディベロップメント 組織特異的および病原体特異的毒性物質ならびにリボザイム
WO2001059124A1 (en) * 2000-02-09 2001-08-16 Sapporo Immuno Diagnostic Laboratory Microplate fluorescent screening method for detecting gene anomaly allowing convenient and less expensive treatment of specimens on mass scale
WO2001075174A2 (en) * 2000-04-03 2001-10-11 Cytyc Corporation Detection and typing of human papillomavirus using pna probes
US6936443B2 (en) * 2000-04-03 2005-08-30 Cytyc Corporation Detection and typing of human papillomavirus using PNA probes
IL162722A0 (en) * 2002-01-07 2005-11-20 Norchip As Method for detecting human papillomarirus mrna
GB0200258D0 (en) * 2002-01-07 2002-02-20 Norchip As Detection of human papillomavirus
GB0404315D0 (en) * 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus
DE102004022350A1 (de) * 2004-04-29 2005-11-17 Genid Gmbh Diagnose von Infektionserkrankungen
DE602005022759D1 (de) 2004-12-08 2010-09-16 Gen Probe Inc Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus
US7524631B2 (en) * 2005-02-02 2009-04-28 Patterson Bruce K HPV E6, E7 mRNA assay and methods of use thereof
US20070031826A1 (en) * 2005-08-05 2007-02-08 My Gene Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof
US9376727B2 (en) 2010-05-25 2016-06-28 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically truncated probes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
JP2633275B2 (ja) * 1986-03-21 1997-07-23 アンステイテユ・パストウール 乳頭腫ウイルス（ｈｐｖ）―３３のゲノムに由来するｄｎａ又はそのｄｎａ断片
DE3625257A1 (de) * 1986-07-23 1988-02-04 Behringwerke Ag Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
US5783412A (en) * 1987-02-26 1998-07-21 Biosearch International Pty. Ltd. Method of detection of carcinogenic human papillomavirus
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
US5182377A (en) * 1988-09-09 1993-01-26 Hoffmann-La Roche Inc. Probes for detection of human papillomavirus

Also Published As

Publication number Publication date
JPH02187000A (ja) 1990-07-23
DK564089A (da) 1990-05-12
DK564089D0 (da) 1989-11-10
CA2002776A1 (en) 1990-05-11
US5750334A (en) 1998-05-12
EP0373352A2 (de) 1990-06-20
ATE133715T1 (de) 1996-02-15
EP0373352B1 (de) 1996-01-31
DE58909587D1 (de) 1996-03-14
DE3838269A1 (de) 1990-05-17
AU4460489A (en) 1990-05-17
DK175222B1 (da) 2004-07-12
FI100474B (fi) 1997-12-15
JP3375623B2 (ja) 2003-02-10
FI895341A0 (fi) 1989-11-09
AU627517B2 (en) 1992-08-27
CA2002776C (en) 2000-04-11
EP0373352A3 (de) 1991-05-15

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