ES2083597T3 - Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado. - Google Patents

Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado.

Info

Publication number
ES2083597T3
ES2083597T3 ES91919614T ES91919614T ES2083597T3 ES 2083597 T3 ES2083597 T3 ES 2083597T3 ES 91919614 T ES91919614 T ES 91919614T ES 91919614 T ES91919614 T ES 91919614T ES 2083597 T3 ES2083597 T3 ES 2083597T3
Authority
ES
Spain
Prior art keywords
treatment
pharmaceutical preparation
coagulation time
prolonged coagulation
prolonged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91919614T
Other languages
English (en)
Inventor
Ole Nordfang
Ulla Hedner
Niels Peter Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of ES2083597T3 publication Critical patent/ES2083597T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

UNA PREPARACION FARMACEUTICA QUE, COMO COMPONENTE ACTIVO CONTIENE UN AGENTE QUE BLOQUEARA LA ACTIVIDAD EPI (INHIBIDOR DE EPI), ES UTIL EN EL TRATAMIENTO DE PACIENTES CON TIEMPO DE COAGULACION PROLONGADO.
ES91919614T 1990-10-31 1991-10-18 Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado. Expired - Lifetime ES2083597T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK261490A DK261490D0 (da) 1990-10-31 1990-10-31 New pharmaceutical compound

Publications (1)

Publication Number Publication Date
ES2083597T3 true ES2083597T3 (es) 1996-04-16

Family

ID=8113744

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91919614T Expired - Lifetime ES2083597T3 (es) 1990-10-31 1991-10-18 Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado.

Country Status (15)

Country Link
EP (1) EP0558529B1 (es)
JP (1) JPH06502171A (es)
AT (1) ATE132757T1 (es)
AU (1) AU657926B2 (es)
CA (1) CA2095356A1 (es)
CZ (1) CZ282497B6 (es)
DE (1) DE69116380T2 (es)
DK (2) DK261490D0 (es)
ES (1) ES2083597T3 (es)
GR (1) GR3019514T3 (es)
HU (1) HUT64236A (es)
RU (1) RU2127600C1 (es)
SK (1) SK282516B6 (es)
UA (1) UA35567C2 (es)
WO (1) WO1992007584A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030171292A1 (en) 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
AU636080B1 (en) * 1992-07-21 1993-04-08 Profy International Corporation Unitary loose sheet binder
RU2195676C2 (ru) * 1999-08-26 2002-12-27 Уральская государственная медицинская академия Способ комплексной оценки прогноза эффективности лечения диффузных заболеваний соединительной ткани низкомолекулярными антикоагулянтами
JP2004505016A (ja) * 2000-05-10 2004-02-19 ノボ　ノルディスク　アクティーゼルスカブ 第ＶＩＩａ因子及び第ＸＩＩＩ因子を含んで成る医薬組成物
US7015194B2 (en) 2000-05-10 2006-03-21 Novo Nordisk A/S Pharmaceutical composition comprising factor VIIa and anti-TFPI
EA200400548A1 (ru) 2001-10-15 2005-06-30 Чирон Корпорейшн Лечение тяжёлой пневмонии путём введения ингибитора пути тканевого фактора (tfpi)
EP1919499A2 (en) * 2005-07-29 2008-05-14 Universiteit van Maastricht Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor
BRPI0914916A2 (pt) 2008-06-30 2015-10-20 Novo Nordisk As anticorpos de interleucina-20 anti-humanos, assim como método de produção dos mesmos
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
KR101792032B1 (ko) * 2008-12-19 2017-11-02 백스터 인터내셔널 인코포레이티드 Ｔｆｐｉ 억제제 및 사용 방법
WO2010072691A1 (en) * 2008-12-22 2010-07-01 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
US8454956B2 (en) 2009-08-31 2013-06-04 National Cheng Kung University Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies
EP3409289B1 (en) * 2010-02-26 2020-09-30 Novo Nordisk A/S Stable antibody containing compositions
PT3345615T (pt) 2010-03-01 2020-01-17 Bayer Healthcare Llc Anticorpos monoclonais otimizados contra inibidor da via do fator tecidual (tfpi)
DK2547355T3 (en) 2010-03-19 2017-03-20 Baxalta GmbH TFPI INHIBITORS AND METHODS OF USE
RU2012153786A (ru) 2010-05-28 2014-07-10 Ново Нордиск А/С Стабильные многодозовые композиции, содержащие антитело и консервант
JP2013533871A (ja) 2010-06-30 2013-08-29 ノヴォ ノルディスク アー／エス 組織因子経路インヒビターに特異的に結合することが可能な抗体
US9228022B2 (en) 2010-06-30 2016-01-05 Novo Nordisk A/S Antibodies that are capable of specifically binding tissue factor pathway inhibitor
BR112014022435B1 (pt) 2012-03-21 2023-02-14 Takeda Pharmaceutical Company Limited Inibidores de tfpi e métodos de uso
WO2014015133A1 (en) 2012-07-19 2014-01-23 National Cheng Kung University Treatment of osteoarthritis using il-20 antagonists
US8603470B1 (en) 2012-08-07 2013-12-10 National Cheng Kung University Use of IL-20 antagonists for treating liver diseases
US8852588B2 (en) 2012-08-07 2014-10-07 National Cheng Kung University Treating allergic airway disorders using anti-IL-20 receptor antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
DE3237512A1 (de) * 1982-10-09 1984-04-12 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von antihaemophilem kryopraezipitat (ahk) und danach hergestelltes antihaemophiles kryopraezipitat
IL87172A (en) * 1987-07-23 1994-12-29 Univ Washington Method of isolating highly purified tissue factor inhibitor
IL87171A (en) * 1987-11-23 1995-08-31 Monsanto Co cDNA of human tissue factor inhibitor
IL89661A (en) 1988-03-17 1999-05-09 Novo Nordisk As Heparin binding proteins
DK148890D0 (da) * 1990-06-19 1990-06-19 Novo Nordisk As Farmaceutisk praeparat

Also Published As

Publication number Publication date
SK282516B6 (sk) 2002-10-08
CZ282497B6 (cs) 1997-07-16
WO1992007584A1 (en) 1992-05-14
HU9301253D0 (en) 1993-07-28
DK261490D0 (da) 1990-10-31
CZ78693A3 (en) 1993-12-15
DE69116380T2 (de) 1996-07-11
SK42893A3 (en) 1993-09-08
EP0558529B1 (en) 1996-01-10
GR3019514T3 (en) 1996-07-31
AU657926B2 (en) 1995-03-30
EP0558529A1 (en) 1993-09-08
UA35567C2 (uk) 2001-04-16
JPH06502171A (ja) 1994-03-10
DK0558529T3 (da) 1996-06-03
ATE132757T1 (de) 1996-01-15
HUT64236A (en) 1993-12-28
RU2127600C1 (ru) 1999-03-20
AU8871191A (en) 1992-05-26
DE69116380D1 (de) 1996-02-22
CA2095356A1 (en) 1992-05-01

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