ES2084867T3 - Comprimido de aspirina de matriz tamponada. - Google Patents

Comprimido de aspirina de matriz tamponada.

Info

Publication number
ES2084867T3
ES2084867T3 ES92107674T ES92107674T ES2084867T3 ES 2084867 T3 ES2084867 T3 ES 2084867T3 ES 92107674 T ES92107674 T ES 92107674T ES 92107674 T ES92107674 T ES 92107674T ES 2084867 T3 ES2084867 T3 ES 2084867T3
Authority
ES
Spain
Prior art keywords
tabled
matrix
tablet
aspirin tablet
aspirin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92107674T
Other languages
English (en)
Inventor
Cynthia M Blase
Garnet E Peck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of ES2084867T3 publication Critical patent/ES2084867T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

UNA TABLETA DE ASPIRINA TAMPONADA COMPUESTA DE UNA MEZCLA UNIFORME DE ASPIRINA CUBIERTA DE POLIMERO DE BASE ACUOSA, UN SISTEMA TAMPONADOR Y UN MATERIAL MATRIZ HIDROFILICO FORMADOR DE GEL. EL SISTEMA TAMPONADOR Y EL MATERIAL MATRIZ PROPORCIONAN UN MICROENTORNO EN UNA DISOLUCION IN VITRO DE PH ALREDEDOR DE 5. LA TABLETA NO REQUIERE EL USO DE VARIAS CAPAS Y PUEDE SER PREPARADA MEDIANTE COMPRESION DIRECTA CON UN EQUIPO CONVENCIONAL.
ES92107674T 1991-05-20 1992-05-07 Comprimido de aspirina de matriz tamponada. Expired - Lifetime ES2084867T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70250491A 1991-05-20 1991-05-20

Publications (1)

Publication Number Publication Date
ES2084867T3 true ES2084867T3 (es) 1996-05-16

Family

ID=24821482

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92107674T Expired - Lifetime ES2084867T3 (es) 1991-05-20 1992-05-07 Comprimido de aspirina de matriz tamponada.

Country Status (11)

Country Link
US (1) US5576024A (es)
EP (1) EP0514711B1 (es)
JP (1) JP3150763B2 (es)
KR (1) KR100225017B1 (es)
AT (1) ATE135222T1 (es)
AU (1) AU636538B2 (es)
CA (1) CA2067975C (es)
DE (1) DE69208934T2 (es)
DK (1) DK0514711T3 (es)
ES (1) ES2084867T3 (es)
GR (1) GR3019826T3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238697B1 (en) 1998-12-21 2001-05-29 Pharmalogix, Inc. Methods and formulations for making bupropion hydrochloride tablets using direct compression
US20020022058A1 (en) * 2000-07-08 2002-02-21 Lovercheck Dale R. Unit dose of material in system and method
FR2881957B1 (fr) 2005-02-16 2008-08-08 Solvay Comprimes comprenant une substance biologiquement active et un excipient

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341416A (en) * 1963-12-11 1967-09-12 Ncr Co Encapsulation of aspirin in ethylcellulose and its product
US3946110A (en) * 1974-05-30 1976-03-23 Peter, Strong Research And Development Company, Inc. Medicinal compositions and methods of preparing the same
US4153677A (en) * 1978-05-18 1979-05-08 Sterling Drug Inc. Controlled-release composition
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
LU85943A1 (fr) * 1985-06-12 1987-01-13 Galephar Comprimes pharmaceutiques permettant l'administration aisee de pellets, leur preparation et leur utilisation
US4857337A (en) * 1988-05-24 1989-08-15 American Home Products Corp. (Del) Enteric coated aspirin tablets
US4869984A (en) * 1988-12-21 1989-09-26 Eastman Kodak Company Electrophotographic elements containing certain naphthoquinone derivatives as electron-transport agents
US4970081A (en) * 1989-01-03 1990-11-13 Sterling Drug Inc. Controlled-release, low-dose aspirin formulation and method of treating vascular occlusive disease therewith

Also Published As

Publication number Publication date
AU636538B2 (en) 1993-04-29
DK0514711T3 (da) 1996-08-12
KR100225017B1 (ko) 1999-10-15
DE69208934T2 (de) 1996-07-25
EP0514711B1 (en) 1996-03-13
KR920021136A (ko) 1992-12-18
DE69208934D1 (de) 1996-04-18
JP3150763B2 (ja) 2001-03-26
US5576024A (en) 1996-11-19
GR3019826T3 (en) 1996-08-31
CA2067975A1 (en) 1992-11-21
EP0514711A1 (en) 1992-11-25
AU1639092A (en) 1992-12-10
JPH05170652A (ja) 1993-07-09
CA2067975C (en) 2003-01-14
ATE135222T1 (de) 1996-03-15

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