ES2085573T3 - Procedimiento de produccion del antibiotico a82810 a partir de actinomadura fibrosa sp. nov. nrrl 18348 y actinomadura sp. nrrl 18880. - Google Patents

Procedimiento de produccion del antibiotico a82810 a partir de actinomadura fibrosa sp. nov. nrrl 18348 y actinomadura sp. nrrl 18880.

Info

Publication number
ES2085573T3
ES2085573T3 ES92308280T ES92308280T ES2085573T3 ES 2085573 T3 ES2085573 T3 ES 2085573T3 ES 92308280 T ES92308280 T ES 92308280T ES 92308280 T ES92308280 T ES 92308280T ES 2085573 T3 ES2085573 T3 ES 2085573T3
Authority
ES
Spain
Prior art keywords
nrrl
actinomadura
nov
antibiotic
fibrosa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92308280T
Other languages
English (en)
Inventor
Laverne Dwaine Boeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2085573T3 publication Critical patent/ES2085573T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/825—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE PRESENTA UN PROCESO MEJORADO PARA PRODUCIR UN ANTIBIOTICO DE POLIETER REPRESENTADO POR A82810 QUE COMPRENDE: (1) EL CULTIVO DE "ACTINOMADURA FIBROSA" SP. NOV. NRRL 18348 O "ACTINOMADURA" SP. NRRL 18880, (2) EL SUMINISTRO DE CASEINA HIDROLIZADA ACIDA EN UNAS PROPORCIONES DE ENTRE 2.50 Y 7.50 GM/L/DIA, (3) EL SUMINISTRO DE GLUCOSA EN UNAS PROPORCIONES DE ENTRE 2.50 Y 7.50 GM/L/DIA, Y (4) EL SUMINISTRO DE PROPIONATO EN UNAS PROPORCIONES DE ENTRE 0.50 Y 1.5 GM/L/DIA AL MEDIO DE CULTIVO APROPIADO DURANTE LA FERMENTACION.
ES92308280T 1991-09-16 1992-09-11 Procedimiento de produccion del antibiotico a82810 a partir de actinomadura fibrosa sp. nov. nrrl 18348 y actinomadura sp. nrrl 18880. Expired - Lifetime ES2085573T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/760,640 US5278053A (en) 1991-09-16 1991-09-16 Method of producing a polyether antibiotic from actinomadura fibrosa sp. nov. NRRL 18348 and actinomadura sp. NRRL 18880

Publications (1)

Publication Number Publication Date
ES2085573T3 true ES2085573T3 (es) 1996-06-01

Family

ID=25059723

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92308280T Expired - Lifetime ES2085573T3 (es) 1991-09-16 1992-09-11 Procedimiento de produccion del antibiotico a82810 a partir de actinomadura fibrosa sp. nov. nrrl 18348 y actinomadura sp. nrrl 18880.

Country Status (6)

Country Link
US (1) US5278053A (es)
EP (1) EP0537897B1 (es)
JP (1) JPH05244973A (es)
CA (1) CA2077837A1 (es)
DE (1) DE69209610T2 (es)
ES (1) ES2085573T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970010603B1 (ko) * 1993-09-17 1997-06-28 신원철 신규 항진균성 항생물질과 이를 생산하는 신규 바실러스 속(Bacillus sp.) 미생물 및 이를 이용한 신규 항진균성 항생물질의 제조방법
US7270947B2 (en) * 2003-01-14 2007-09-18 Cognis Corporation Method for controlling biooxidation reactions
JP5578649B2 (ja) * 2009-11-06 2014-08-27 浩治 宮野内 アクチノマデュラ属に属する新規微生物、その微生物が産生する新規化合物、及びその化合物を有効成分とする医薬
AR097805A1 (es) 2013-03-15 2016-04-20 Alder Biopharmaceuticals Inc Células de cambio de temperatura para la expresión de alto rendimiento de polipéptidos en levadura y otros transformados

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU516543B2 (en) * 1977-05-31 1981-06-11 Kaken Chemical Co. Ltd. Polyether type antibiotics
HU203789B (en) * 1988-02-08 1991-09-30 Pfizer Process for producing polycyclic acidic ether-type antibiotica of anticoccidial and growth-stimulating activity
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
RU1825377C (ru) * 1988-05-02 1993-06-30 Эли Лилли Энд Компани Способ получени антибиотика А 82810 или его производных, и штамм АстINомаDURа FIвRоSа - продуцент антибиотика А 82810
US5098834A (en) * 1988-05-02 1992-03-24 Eli Lilly And Company Process for producing antibiotic A8210 which comprises cultivating Actinomadura Fibrosa sp nov. NRRL 18348, or an A82810-producing mutant thereof

Also Published As

Publication number Publication date
US5278053A (en) 1994-01-11
CA2077837A1 (en) 1993-03-17
JPH05244973A (ja) 1993-09-24
EP0537897B1 (en) 1996-04-03
DE69209610T2 (de) 1996-09-05
EP0537897A1 (en) 1993-04-21
DE69209610D1 (de) 1996-05-09

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