ES2085908T3 - Antigenos de la glucoproteina transmembranica de cubierta de un retrovirus humano del tipo hiv-2 (antigenos que presentan entre ellos un parentesco inmunologico). - Google Patents

Antigenos de la glucoproteina transmembranica de cubierta de un retrovirus humano del tipo hiv-2 (antigenos que presentan entre ellos un parentesco inmunologico).

Info

Publication number
ES2085908T3
ES2085908T3 ES90908240T ES90908240T ES2085908T3 ES 2085908 T3 ES2085908 T3 ES 2085908T3 ES 90908240 T ES90908240 T ES 90908240T ES 90908240 T ES90908240 T ES 90908240T ES 2085908 T3 ES2085908 T3 ES 2085908T3
Authority
ES
Spain
Prior art keywords
antigens
glycoprotein
type
hiv
transmembranic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90908240T
Other languages
English (en)
Inventor
Ara Hovanessian
Maire-Anne Rey
Anne Laurent
Bernard Krust
Luc Montagnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8906322A external-priority patent/FR2646854A1/fr
Priority claimed from US07/356,459 external-priority patent/US5208321A/en
Application filed by Institut Pasteur filed Critical Institut Pasteur
Application granted granted Critical
Publication of ES2085908T3 publication Critical patent/ES2085908T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UNA GLYCOPROTEINA ANTIGENICA GP 80 CARACTERIZADA POR LAS SIGUIENTES PROPIEDADES: TIENE UN PESO MOLECULAR (PM) DE CERCA DE 80 KDA, SE LA RECONOCE POR LOS ANTICUERPOS POLYCLONALES DIRIGIDOS CONTRA LA GLYCOPROTEINA GP300, COMPRENDE EN ASOCIACION BAJO LA FORMA DE DIMERE, DOS ENTIDADES DE LA GLYCOPROTEINA TRANSMEMBRANADA DE ENVOLTURA GP36, CODIFICADA POR GENOME DE UN RETROVIRUS HUMANO DEL TIPO HIV-2, SUSCEPTIBLE DE PROVOCAR EL SLA O EL SIDA EN EL HOMBRE, O TODA LA GLYCOPROTEINA DE PESO MOLECULAR DEL MISMO ORDEN DE TAMAÑO, CAPAZ DE FORMAR UN COMPLEJO INMUNOLOGICO DEL TIPO ANTIGENO-ANTICUERPO, CON ANTICUERPOS DIRIGIDOS CONTRA LA CITADA GP80. LA INVENCION HACE ALUSION IGUALMENTE A LOS ANTICUERPOS DIRIGIDOS CONTRA ESTA GLYCOPROTEINA. SU APLICACION SE REFIERE TAMBIEN AL DIAGNOSTICO Y A LA VACUNA.
ES90908240T 1989-05-12 1990-05-11 Antigenos de la glucoproteina transmembranica de cubierta de un retrovirus humano del tipo hiv-2 (antigenos que presentan entre ellos un parentesco inmunologico). Expired - Lifetime ES2085908T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8906322A FR2646854A1 (fr) 1989-05-12 1989-05-12 Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique
US07/356,459 US5208321A (en) 1988-06-09 1989-05-25 HIV-2 transmembrane glycoprotein homodimer (GP 80)

Publications (1)

Publication Number Publication Date
ES2085908T3 true ES2085908T3 (es) 1996-06-16

Family

ID=26227325

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90908240T Expired - Lifetime ES2085908T3 (es) 1989-05-12 1990-05-11 Antigenos de la glucoproteina transmembranica de cubierta de un retrovirus humano del tipo hiv-2 (antigenos que presentan entre ellos un parentesco inmunologico).

Country Status (11)

Country Link
EP (1) EP0424519B1 (es)
JP (5) JP3534746B2 (es)
AT (1) ATE136789T1 (es)
CA (1) CA2032505C (es)
DE (1) DE69026569T2 (es)
DK (1) DK0424519T3 (es)
ES (1) ES2085908T3 (es)
HK (1) HK219796A (es)
OA (1) OA09634A (es)
SG (1) SG48125A1 (es)
WO (1) WO1990013314A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256561A (en) * 1991-12-20 1993-10-26 Abbott Laboratories Monoclonal antibody to HIV-2 and uses thereof
FR2692898B1 (fr) * 1992-06-30 1995-06-02 Centre Nat Rech Scient Procédé d'obtention de protéines membranaires, et utilisation de ces protéines dans un but de diagnostic ou de vaccination.
JP2013040148A (ja) * 2011-08-19 2013-02-28 Asahi Kasei Corp シアリルオリゴ糖ペプチド固定化ビーズ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0239425B1 (fr) * 1986-01-22 1989-11-02 Institut Pasteur Rétrovirus du type HIV-2 susceptible de provoquer le SIDA, et ses constituants antigéniques et nucléiques
EP0269520A3 (fr) * 1986-11-21 1988-08-24 Institut Pasteur Rétrovirus du type HIV-2 susceptible de provoquer le sida, et ses constituants antigéniques et nucléiques
JP2948823B2 (ja) * 1987-01-16 1999-09-13 アンステイテユ・パストウール ヒト免疫不全レトロウィルス（ｈｉｖ）関連抗原性ペプチド、そのウィルス感染の検出及びワクチンへの使用
FR2620030B1 (fr) * 1987-09-07 1990-03-23 Transgene Sa Vecteur d'expression des proteines du virus hiv-2, un agent causal du sida, culture cellulaire infectee ou transformee par ce vecteur, proteines obtenues, vaccin et anticorps obtenus

Also Published As

Publication number Publication date
DE69026569T2 (de) 1996-09-05
JP2003146999A (ja) 2003-05-21
SG48125A1 (en) 1998-04-17
EP0424519B1 (fr) 1996-04-17
OA09634A (fr) 1993-04-30
DE69026569D1 (de) 1996-05-23
JP2008156350A (ja) 2008-07-10
CA2032505A1 (fr) 1990-11-13
WO1990013314A3 (fr) 1990-12-27
WO1990013314A2 (fr) 1990-11-15
DK0424519T3 (da) 1996-05-13
JP3833681B2 (ja) 2006-10-18
JPH03506042A (ja) 1991-12-26
JP2005170949A (ja) 2005-06-30
JP3534746B2 (ja) 2004-06-07
HK219796A (en) 1997-01-03
CA2032505C (fr) 2001-07-10
JP4174591B2 (ja) 2008-11-05
EP0424519A1 (fr) 1991-05-02
JP2006213702A (ja) 2006-08-17
ATE136789T1 (de) 1996-05-15
JP4423374B2 (ja) 2010-03-03

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