ES2086409T3 - Imidazolinas sustituidas en posicion 2 y preparacion y uso de las mismas. - Google Patents

Imidazolinas sustituidas en posicion 2 y preparacion y uso de las mismas.

Info

Publication number
ES2086409T3
ES2086409T3 ES90912283T ES90912283T ES2086409T3 ES 2086409 T3 ES2086409 T3 ES 2086409T3 ES 90912283 T ES90912283 T ES 90912283T ES 90912283 T ES90912283 T ES 90912283T ES 2086409 T3 ES2086409 T3 ES 2086409T3
Authority
ES
Spain
Prior art keywords
preparation
same
substituted imidazolines
imidazolines
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90912283T
Other languages
English (en)
Inventor
Poul Borrevang
Henrik Sune Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of ES2086409T3 publication Critical patent/ES2086409T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lubricants (AREA)
  • Nonmetallic Welding Materials (AREA)
  • External Artificial Organs (AREA)
  • Fertilizers (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVAS 2-IMIDAZOLINAS SUSTITUIDAS (I) QUE TIENEN UN EFECTO REDUCTOR DE LA GLUCOSA DE LA SANGRE EN MAMIFEROS, A SU PREPARACION, A LAS COMPOSICIONES FARMACEUTICAS QUE LAS CONTIENEN Y A SU USO.
ES90912283T 1989-07-12 1990-07-12 Imidazolinas sustituidas en posicion 2 y preparacion y uso de las mismas. Expired - Lifetime ES2086409T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK344489A DK344489D0 (da) 1989-07-12 1989-07-12 Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Publications (1)

Publication Number Publication Date
ES2086409T3 true ES2086409T3 (es) 1996-07-01

Family

ID=8122944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90912283T Expired - Lifetime ES2086409T3 (es) 1989-07-12 1990-07-12 Imidazolinas sustituidas en posicion 2 y preparacion y uso de las mismas.

Country Status (22)

Country Link
US (1) US5262430A (es)
EP (1) EP0482108B1 (es)
JP (1) JPH04506968A (es)
KR (1) KR927003578A (es)
CN (1) CN1049343A (es)
AT (1) ATE135703T1 (es)
AU (1) AU637393B2 (es)
CA (1) CA2064095A1 (es)
DD (1) DD296489A5 (es)
DE (1) DE69026087T2 (es)
DK (2) DK344489D0 (es)
ES (1) ES2086409T3 (es)
FI (1) FI920118A7 (es)
GR (1) GR1000716B (es)
IE (1) IE74210B1 (es)
IL (1) IL95046A (es)
NO (1) NO920143L (es)
NZ (1) NZ234451A (es)
PT (1) PT94685B (es)
WO (1) WO1991000862A1 (es)
YU (1) YU136390A (es)
ZA (1) ZA905422B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201709A1 (de) * 1992-01-23 1993-07-29 Bayer Ag (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide
US5750543A (en) * 1996-02-01 1998-05-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
US20090162342A1 (en) * 2001-06-07 2009-06-25 Sanomune Inc. Therapeutic uses of glandular kallikrein
ES2340180T3 (es) * 2004-06-01 2010-05-31 F.Hoffmann-La Roche Ag 3-amino-1-arilpropil-indoles como inhibidores de reabsorcion de monoaminas.
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
EP2854841B1 (en) 2012-06-04 2017-02-22 Diamedica Inc. Human tissue kallikrein 1 glycosylation isoforms
CN110446501A (zh) 2017-03-09 2019-11-12 代阿麦迪卡股份有限公司 组织激肽释放酶1的剂型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
ZW13782A1 (en) * 1981-07-28 1982-10-06 Reckitt & Colmann Prod Ltd Imidazoline derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
EP0482108B1 (en) 1996-03-20
EP0482108A1 (en) 1992-04-29
US5262430A (en) 1993-11-16
GR900100535A (en) 1991-12-10
KR927003578A (ko) 1992-12-18
PT94685A (pt) 1991-03-20
DE69026087T2 (de) 1996-08-29
PT94685B (pt) 1997-04-30
NO920143D0 (no) 1992-01-10
NO920143L (no) 1992-03-04
IL95046A0 (en) 1991-06-10
IL95046A (en) 1995-03-15
IE902546A1 (en) 1991-02-27
WO1991000862A1 (en) 1991-01-24
CN1049343A (zh) 1991-02-20
AU6164490A (en) 1991-02-06
FI920118A0 (fi) 1992-01-10
ZA905422B (en) 1991-03-27
ATE135703T1 (de) 1996-04-15
FI920118A7 (fi) 1992-01-10
IE74210B1 (en) 1997-07-16
JPH04506968A (ja) 1992-12-03
YU136390A (sh) 1993-10-20
NZ234451A (en) 1991-08-27
GR1000716B (el) 1992-11-23
DE69026087D1 (de) 1996-04-25
DD296489A5 (de) 1991-12-05
CA2064095A1 (en) 1991-01-13
AU637393B2 (en) 1993-05-27
DK0482108T3 (da) 1996-07-22
DK344489D0 (da) 1989-07-12

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