ES2086644T3 - Preparado anovulatorio para la contracepcion hormonal. - Google Patents
Preparado anovulatorio para la contracepcion hormonal.Info
- Publication number
- ES2086644T3 ES2086644T3 ES92250018T ES92250018T ES2086644T3 ES 2086644 T3 ES2086644 T3 ES 2086644T3 ES 92250018 T ES92250018 T ES 92250018T ES 92250018 T ES92250018 T ES 92250018T ES 2086644 T3 ES2086644 T3 ES 2086644T3
- Authority
- ES
- Spain
- Prior art keywords
- hormonal
- component
- preparation
- units
- anovulatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003054 hormonal effect Effects 0.000 title abstract 8
- 230000002513 anti-ovulatory effect Effects 0.000 title 1
- 230000016087 ovulation Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
EL MEDIO QUE IMPIDE LA OVULACION QUE SIRVE PARA LA CONTRACEPCION HORMONAL DISPONE DE DOS COMPONENTES HORMONALES QUE SE ADMINISTRAN DE FORMA ORAL Y QUE ESTAN COLOCADOS EN UNA CAJA QUE LOS MANTIENE SEPARADOS. EL PRIMER COMPONENTE ES UN PREPARADO OSTROGENAL QUE INFLUYE EXCLUSIVAMENTE EN LA DISTORSION DE LA MADUREZ DEL FOLICULO. EL SEGUNDO COMPONENTE CONTIENE UNA COMBINACION DEL PREPARADO OSTROGENAL Y DE OTRO PREPARADO QUE DOSIFICA LA OVULACION. ESTOS COMPONENTES SE CARACTERIZAN PORQUE EL NUMERO TOTAL DE LAS UNIDADES HORMONALES ES IGUAL QUE EL DEL PERIODO. EL PRIMER COMPONENTE HORMONAL TIENE DE 5 A 14 UNIDADES Y EL SEGUNDO COMPONENTE HORMONAL TIENE DE 23 A 14 UNIDADES. EL NUMERO DE UNIDADES DIARIAS DEL PRIMER COMPONENTE HORMONAL ES MENOR QUE EL NUMERO DE UNIDADES DIARIAS QUE EL SEGUNDO COMPONENTE HORMONAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4104385A DE4104385C1 (es) | 1991-02-09 | 1991-02-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2086644T3 true ES2086644T3 (es) | 1996-07-01 |
| ES2086644T5 ES2086644T5 (es) | 2002-11-16 |
Family
ID=6424973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92250018T Expired - Lifetime ES2086644T5 (es) | 1991-02-09 | 1992-01-22 | Preparado anovulatorio para la contracepcion hormonal. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5280023A (es) |
| EP (1) | EP0499348B2 (es) |
| JP (1) | JP2852985B2 (es) |
| AT (1) | ATE136781T1 (es) |
| AU (2) | AU669327B2 (es) |
| BR (1) | BR9204121A (es) |
| CA (1) | CA2079002C (es) |
| DE (2) | DE4104385C1 (es) |
| DK (1) | DK0499348T4 (es) |
| ES (1) | ES2086644T5 (es) |
| FI (1) | FI98888C (es) |
| GR (1) | GR3019833T3 (es) |
| HU (1) | HU218663B (es) |
| NO (1) | NO179696C (es) |
| RU (1) | RU2091069C1 (es) |
| WO (1) | WO1992013539A1 (es) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4224534A1 (de) * | 1992-07-24 | 1994-01-27 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
| DE4313926A1 (de) * | 1993-04-28 | 1994-11-03 | Jenapharm Gmbh | Pharmazeutisches Mehrphasenpräparat zur hormonalen Kontrazeption |
| US6407082B1 (en) * | 1996-09-13 | 2002-06-18 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a vitamin D compound |
| DE4321957C2 (de) * | 1993-07-01 | 1995-09-28 | Marika Dr Med Ehrlich | Verwendung eines hormonalen Mittels zur Therapie der Akne |
| DE4344405C2 (de) * | 1993-12-24 | 1995-12-07 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption |
| DE4405591C1 (de) * | 1994-02-22 | 1995-07-20 | Hesch Rolf Dieter Prof Dr Med | Mittel zur postmenopausalen Hormonsubstitution |
| DE4411585A1 (de) * | 1994-03-30 | 1995-10-05 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
| DE4429374C1 (de) | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| DE19504227C2 (de) * | 1995-02-09 | 1999-04-29 | Klaus Dr Med Umbreit | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
| DE19513662A1 (de) * | 1995-04-08 | 1996-10-10 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
| US20050032756A1 (en) * | 1995-10-28 | 2005-02-10 | Michael Dittgen | Multistage preparation for contraception based on natural estrogens |
| DE19540253C2 (de) * | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
| US5747480A (en) * | 1996-05-08 | 1998-05-05 | American Home Products Corporation | Oral contraceptive |
| WO1998004267A1 (en) * | 1996-07-26 | 1998-02-05 | American Home Products Corporation | Progestin/estrogen oral contraceptive |
| US6451778B1 (en) | 1996-07-26 | 2002-09-17 | Wyeth | Oral contraceptive |
| US5888543A (en) * | 1996-07-26 | 1999-03-30 | American Home Products Corporation | Oral contraceptives |
| US5858405A (en) * | 1996-07-26 | 1999-01-12 | American Home Products Corporation | Oral contraceptive |
| US6479475B1 (en) | 1996-07-26 | 2002-11-12 | Wyeth | Oral contraceptive |
| US6765002B2 (en) | 2000-03-21 | 2004-07-20 | Gustavo Rodriguez | Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium |
| US6511970B1 (en) | 1996-09-13 | 2003-01-28 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium |
| US6028064A (en) | 1996-09-13 | 2000-02-22 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of progestin products |
| US6034074A (en) | 1996-09-13 | 2000-03-07 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a Vitamin D compound |
| JP2001513566A (ja) * | 1997-08-27 | 2001-09-04 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 経口避妊における、エストロゲンと子宮内膜節約性プロゲスチンおよび子宮内膜萎縮性プロゲスチンとの組み合わせ物 |
| US6251956B1 (en) | 1998-08-20 | 2001-06-26 | Ortho Pharmaceutical Corporation | Combination progestin oral contraceptive regimen |
| US6855703B1 (en) | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
| US7459445B2 (en) * | 2000-03-10 | 2008-12-02 | Duramed Pharmaceuticals, Inc. | Estrogenic compounds and topical pharmaceutical formulations of the same |
| US6660726B2 (en) | 2000-03-10 | 2003-12-09 | Endeavor Pharmaceuticals | Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same |
| US7989436B2 (en) * | 2003-07-23 | 2011-08-02 | Duramed Pharmaceuticals, Inc. | Estrogenic compounds and pharmaceutical formulations comprising the same |
| US20050113351A1 (en) * | 2000-03-21 | 2005-05-26 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
| US20040176336A1 (en) * | 2000-03-21 | 2004-09-09 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
| US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
| NZ591627A (en) | 2001-12-05 | 2012-09-28 | Teva Womens Health Inc | Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology |
| US6992075B2 (en) | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
| CA2521471A1 (en) * | 2003-04-11 | 2004-10-28 | Barr Laboratories, Inc. | Methods of administering estrogens and progestins |
| NZ545130A (en) * | 2003-07-16 | 2009-03-31 | Duramed Pharmaceuticals Inc | Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration |
| DE102004019743B4 (de) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| DE102004026671A1 (de) | 2004-05-28 | 2005-12-15 | Grünenthal GmbH | Darreichungsform zur hormonalen Kontrazeption |
| DE102004026669A1 (de) * | 2004-05-28 | 2005-12-15 | Grünenthal GmbH | Verwendung einer Kombination aus Ethinylestradiol und Chlormadinonacetat zur Herstellung eines Arzneimittels |
| DE102004026670A1 (de) * | 2004-05-28 | 2005-12-15 | Grünenthal GmbH | Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat |
| US20070111975A1 (en) * | 2004-10-07 | 2007-05-17 | Duramed Pharmaceuticals, Inc. | Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens |
| US20060100566A1 (en) * | 2004-11-05 | 2006-05-11 | Women's Medical Research Group, Llc | Apparatus and method for the treatment of dysmenorrhea |
| EP1853272A1 (en) * | 2005-02-03 | 2007-11-14 | Duramed Pharmaceuticals, Inc. | Compositions of unconjugated estrogens and methods for their use |
| US7704984B2 (en) | 2005-04-22 | 2010-04-27 | Warner Chilcott Company, Llc | Extended estrogen dosing contraceptive regimen |
| US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6615481A (es) † | 1966-11-02 | 1968-05-03 | ||
| US3639600A (en) † | 1969-08-28 | 1972-02-01 | Upjohn Co | Process of establishing cyclicity in a human female |
| US3733407A (en) * | 1971-08-25 | 1973-05-15 | Syntex Corp | Menopause treatment |
| DE2431704A1 (de) * | 1974-07-02 | 1976-01-22 | Asche Ag | Stufenkombinationspraeparate per kontrazeption |
| DE2645307A1 (de) * | 1976-10-05 | 1978-04-06 | Schering Ag | Neue mittel und neue methoden zur behandlung klimakterischer ausfallerscheinungen |
| NL8001593A (nl) * | 1980-03-18 | 1981-10-16 | Akzo Nv | Meerfasisch combinatiepreparaat voor orale anticonceptie. |
| US4921843A (en) * | 1988-10-20 | 1990-05-01 | Pasquale Samuel A | Contraception system and method |
| AU630334B2 (en) * | 1987-09-24 | 1992-10-29 | Jencap Research Ltd. | Hormone preparations for hormone replacement therapy and contraceptive method |
| EP0368373A1 (en) * | 1988-10-13 | 1990-05-16 | Akzo Nobel N.V. | Multi-phase contraceptive preparation |
-
1991
- 1991-02-09 DE DE4104385A patent/DE4104385C1/de not_active Expired - Lifetime
-
1992
- 1992-01-22 AT AT92250018T patent/ATE136781T1/de not_active IP Right Cessation
- 1992-01-22 DE DE59205986T patent/DE59205986D1/de not_active Expired - Fee Related
- 1992-01-22 EP EP92250018A patent/EP0499348B2/de not_active Expired - Lifetime
- 1992-01-22 DK DK92250018T patent/DK0499348T4/da active
- 1992-01-22 ES ES92250018T patent/ES2086644T5/es not_active Expired - Lifetime
- 1992-02-06 JP JP4021079A patent/JP2852985B2/ja not_active Expired - Lifetime
- 1992-02-07 WO PCT/DE1992/000081 patent/WO1992013539A1/de not_active Ceased
- 1992-02-07 CA CA002079002A patent/CA2079002C/en not_active Expired - Fee Related
- 1992-02-07 RU SU925053226A patent/RU2091069C1/ru active
- 1992-02-07 BR BR929204121A patent/BR9204121A/pt not_active Application Discontinuation
- 1992-02-07 HU HU9203197A patent/HU218663B/hu not_active IP Right Cessation
- 1992-02-07 AU AU11910/92A patent/AU669327B2/en not_active Ceased
- 1992-02-10 US US07/833,294 patent/US5280023A/en not_active Expired - Fee Related
- 1992-10-05 NO NO923874A patent/NO179696C/no not_active IP Right Cessation
- 1992-10-07 FI FI924519A patent/FI98888C/fi active
-
1993
- 1993-10-06 US US08/132,287 patent/US5510341A/en not_active Expired - Fee Related
-
1996
- 1996-04-09 AU AU50538/96A patent/AU692376B2/en not_active Ceased
- 1996-05-06 GR GR960401208T patent/GR3019833T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO923874D0 (no) | 1992-10-05 |
| EP0499348B2 (de) | 2002-03-27 |
| DK0499348T4 (da) | 2002-06-10 |
| EP0499348B1 (de) | 1996-04-17 |
| CA2079002A1 (en) | 1992-08-10 |
| ATE136781T1 (de) | 1996-05-15 |
| FI924519L (fi) | 1992-10-07 |
| US5510341A (en) | 1996-04-23 |
| ES2086644T5 (es) | 2002-11-16 |
| RU2091069C1 (ru) | 1997-09-27 |
| CA2079002C (en) | 1998-07-28 |
| AU692376B2 (en) | 1998-06-04 |
| EP0499348A1 (de) | 1992-08-19 |
| DE59205986D1 (de) | 1996-05-23 |
| JP2852985B2 (ja) | 1999-02-03 |
| US5280023A (en) | 1994-01-18 |
| NO923874L (no) | 1992-10-05 |
| HU9203197D0 (en) | 1992-12-28 |
| AU669327B2 (en) | 1996-06-06 |
| JPH0558909A (ja) | 1993-03-09 |
| WO1992013539A1 (de) | 1992-08-20 |
| FI98888C (fi) | 1997-09-10 |
| GR3019833T3 (en) | 1996-08-31 |
| NO179696C (no) | 1996-12-04 |
| FI98888B (fi) | 1997-05-30 |
| HU218663B (hu) | 2000-10-28 |
| HUT64229A (en) | 1993-12-28 |
| AU5053896A (en) | 1996-06-27 |
| AU1191092A (en) | 1992-09-07 |
| DE4104385C1 (es) | 1992-08-13 |
| BR9204121A (pt) | 1993-06-08 |
| FI924519A0 (fi) | 1992-10-07 |
| NO179696B (no) | 1996-08-26 |
| DK0499348T3 (da) | 1996-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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