ES2086800T3 - Procedimiento para la preparacion de 6-hidroxi-2,5,7,8-tetraalquil-2-(4-aminofenoximetil)cromanos. - Google Patents

Procedimiento para la preparacion de 6-hidroxi-2,5,7,8-tetraalquil-2-(4-aminofenoximetil)cromanos.

Info

Publication number
ES2086800T3
ES2086800T3 ES93102566T ES93102566T ES2086800T3 ES 2086800 T3 ES2086800 T3 ES 2086800T3 ES 93102566 T ES93102566 T ES 93102566T ES 93102566 T ES93102566 T ES 93102566T ES 2086800 T3 ES2086800 T3 ES 2086800T3
Authority
ES
Spain
Prior art keywords
preparation
aminophenoximetil
chromanes
tetraalkyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93102566T
Other languages
English (en)
Inventor
Josef Dr Heveling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Sankyo Co Ltd
Original Assignee
Lonza AG
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG, Sankyo Co Ltd filed Critical Lonza AG
Application granted granted Critical
Publication of ES2086800T3 publication Critical patent/ES2086800T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)

Abstract

SE DESCRIBE UN NUEVO PROCESO PARA LA FABRICACION DE AMINO CROMANOS DE LA FORMULA GENERAL DONDE UN NITROCROMANO DE LA FORMULA GENERAL SE HIDROGENA CON HIDROGENO EN PRESENCIA DE UN CATALIZADOR DE HIDROGENACION, CON REDUCCION DEL AMINOCROMANO (III) RESULTANTE CON OXIDO DE ZIRCONIO/ISOPROPANOL PARA LA OBTENCION DE AMINOCROMENO (IV). LOS AMINOCROMANOS SON PRODUCTOS INTERMEDIOS DE VALOR COMPLETO PARA LA FABRICACION DE COMPUESTOS FARMACEUTICOS REDUCTORES DE LIPIDOS.
ES93102566T 1992-02-21 1993-02-18 Procedimiento para la preparacion de 6-hidroxi-2,5,7,8-tetraalquil-2-(4-aminofenoximetil)cromanos. Expired - Lifetime ES2086800T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH53292 1992-02-21

Publications (1)

Publication Number Publication Date
ES2086800T3 true ES2086800T3 (es) 1996-07-01

Family

ID=4189171

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93102566T Expired - Lifetime ES2086800T3 (es) 1992-02-21 1993-02-18 Procedimiento para la preparacion de 6-hidroxi-2,5,7,8-tetraalquil-2-(4-aminofenoximetil)cromanos.

Country Status (11)

Country Link
US (1) US5310952A (es)
EP (1) EP0556830B1 (es)
JP (1) JPH05255301A (es)
KR (1) KR930017889A (es)
AT (1) ATE137232T1 (es)
CA (1) CA2089012A1 (es)
DE (1) DE59302306D1 (es)
DK (1) DK0556830T3 (es)
ES (1) ES2086800T3 (es)
GR (1) GR3019766T3 (es)
TW (1) TW223070B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457124A (en) * 1993-12-07 1995-10-10 Hoffmann-La Roche Inc. Carboxylic acid Leukotriene B4 antagonists
WO2000008009A1 (en) * 1998-08-04 2000-02-17 Sankyo Company, Limited Process for the preparation of 2-(aminophenoxymethyl) chromans
US7608395B2 (en) * 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
KR100784850B1 (ko) * 2006-10-19 2007-12-14 충북대학교 산학협력단 크로만-2-카복실산 아릴아마이드 유도체, 그 제조방법 및이를 포함하는 ＮＦ-κＢ 저해제
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
DK173350B1 (da) * 1985-02-26 2000-08-07 Sankyo Co Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
ATE96127T1 (de) * 1989-05-02 1993-11-15 Lonza Ag Sinterfaehiges zirkonoxidpulver und verfahren zu seiner herstellung.

Also Published As

Publication number Publication date
EP0556830B1 (de) 1996-04-24
DE59302306D1 (de) 1996-05-30
US5310952A (en) 1994-05-10
GR3019766T3 (en) 1996-07-31
ATE137232T1 (de) 1996-05-15
EP0556830A1 (de) 1993-08-25
JPH05255301A (ja) 1993-10-05
TW223070B (es) 1994-05-01
KR930017889A (ko) 1993-09-20
DK0556830T3 (da) 1996-05-13
CA2089012A1 (en) 1993-08-22

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