ES2089009T3 - Aparato y metodos para ensayar la susceptibilidad antimicrobiana de microorganismos. - Google Patents

Aparato y metodos para ensayar la susceptibilidad antimicrobiana de microorganismos.

Info

Publication number
ES2089009T3
ES2089009T3 ES90902964T ES90902964T ES2089009T3 ES 2089009 T3 ES2089009 T3 ES 2089009T3 ES 90902964 T ES90902964 T ES 90902964T ES 90902964 T ES90902964 T ES 90902964T ES 2089009 T3 ES2089009 T3 ES 2089009T3
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ES
Spain
Prior art keywords
test
growth
well
volume
control well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90902964T
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English (en)
Other versions
ES2089009T5 (es
Inventor
Michael V Lancaster
Rebecca D Fields
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alamar Biosciences Laboratory Inc
Original Assignee
Alamar Biosciences Laboratory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23151214&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2089009(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alamar Biosciences Laboratory Inc filed Critical Alamar Biosciences Laboratory Inc
Publication of ES2089009T3 publication Critical patent/ES2089009T3/es
Application granted granted Critical
Publication of ES2089009T5 publication Critical patent/ES2089009T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

METODO Y APARATO PARA PROBAR LA SUSCEPTIBILIDAD CUALITATIVA DE UN MICROORGANISMO A LA INHIBICION DE CRECIMIENTO POR UN PRODUCTO ANTIMICROBIANO UTILIZANDO UN PANEL DE PRUEBAS (100-1). LOS MODULOS DE PRUEBA (107, 108, 109) ESTAN EN UN POZO DE CONTROL DE CRECIMIENTO NEGATIVA (101), UN POZO DE CONTROL DE CRECIMIENTO POSITIVA (102) Y UN POZO DE PRUEBA (103). LOS MODULOS DE PRUEBA TIENEN UN VOLUMEN SOLIDO SECO DE UN SUBGRUPO DE LOS CONSTITUYENTES DE UN GRUPO DE COMPUESTOS QUIMICOS DE PRUEBA QUE CONTIENEN RESAZURINA Y UN MEDIO DE CRECIMIENTO. EL MODULO DE PRUEBA (109) QUE SE ENCUENTRA EN EL POZO DE PRUEBA TIENE ADEMAS UN VOLUMEN DE PRODUCTO ANTIMICROBIANO. EL MODULO DE PRUEBA (107) QUE SE ENCUENTRA EN EL POZO DE CONTROL DE CRECIMIENTO NEGATIVA SE REHIDRATA CON UN VOLUMEN DE LIQUIDO ESTERIL (110) QUE CONTIENE EL RESTO DE TODOS LOS COMPONENTES QUIMICOS DE PRUEBA QUE NO SE ENCUENTRAN EN EL MODULO DE PRUEBA. LOS MODULOS DE PRUEBA (108, 109) QUE SE ENCUENTRAN EN EL POZO DE CONTROL DE CRECIMIENTO POSITIVA Y EN EL POZO DE PRUEBA SE VUELVEN A HIDRATAR CON UN VOLUMEN DE INOCULO LIQUIDO (112, 113) QUE CONTIENE EL RESTO DE LOS CONSTITUYENTES JUNTO CON UNA CONCENTRACION DE MICROORGANISMOS . EL PANEL DE PRUEBA (100-1) ES INCUBADO Y LEIDO A CONTINUACION UTILIZANDO UN PROTOCOLO DE LECTURA DE LUZ VISIBLE O UN PROTOCOLO DE LECTURA DE EXCITACION FLUORESCENTE PARA DETERMINAR EL CRECIMIENTO O NO CRECIMIENTO QUE TIENE LUGAR EN LOS POZOS. EL PROTOCOLO DE LECTURA DE LUZ VISIBLE DETERMINA EL CRECIMIENTO DEL ORGANISMO ANTE LA PRESENCIA DE UN CAMBIO DE COLOR DE AZUL A ROJO. LOS MODULOS DE PRUEBA SON PREFERIBLEMENTE , DISCOS DE PAPEL CON REACTIVOS DE PRUEBA ABSORBIDOS EN SU INTERIOR Y LA CONCENTRACION DEL PRODUCTO ANTIMICROBIANO IMPRESO SOBRE EL.
ES90902964T 1989-01-17 1990-01-16 Aparato y metodos para ensayar la susceptibilidad antimicrobiana de microorganismos. Expired - Lifetime ES2089009T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29859989A 1989-01-17 1989-01-17
US298599 1989-01-17

Publications (2)

Publication Number Publication Date
ES2089009T3 true ES2089009T3 (es) 1996-10-01
ES2089009T5 ES2089009T5 (es) 2008-05-16

Family

ID=23151214

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90902964T Expired - Lifetime ES2089009T5 (es) 1989-01-17 1990-01-16 Aparato y metodos para ensayar la susceptibilidad antimicrobiana de microorganismos.

Country Status (8)

Country Link
EP (1) EP0454784B2 (es)
JP (2) JPH04502707A (es)
AT (1) ATE136939T1 (es)
AU (1) AU5040990A (es)
CA (1) CA2044265C (es)
DE (1) DE69026602T3 (es)
ES (1) ES2089009T5 (es)
WO (1) WO1990008196A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992012257A1 (en) * 1990-12-28 1992-07-23 Baxter Diagnostics Inc. Method and composition for determining antimicrobial susceptibility of the majority of clinically significant gram positive organisms
AU4756393A (en) * 1992-09-30 1994-04-14 Becton Dickinson & Company Method of critical speciman resistance testing
DE4316394C1 (de) * 1993-05-17 1994-06-23 Biotest Ag Verfahren zum optischen Nachweis von Mikroorganismen, ihrer Identifizierung und der Empfindlichkeitstestung gegen Antibiotika unter Verwendung eines Redoxindikatorsystems, umfassend Methylenblau und Resazurin
US5863751A (en) * 1996-09-30 1999-01-26 Becton Dickinson And Company Addition of lactose or other sugars in correcting false susceptibility results for resistant microorganisms in antimicrobial susceptibility tests
JP2000116399A (ja) * 1998-10-14 2000-04-25 Eiken Chem Co Ltd 薬剤感受性菌・薬剤耐性菌鑑別用分画培地および鑑別方法
WO2000067037A2 (en) * 1999-04-29 2000-11-09 Dade Microscan Inc. A combined rapid anti-microbial susceptibility assay and microorganism identification system
US6440689B1 (en) * 1999-12-30 2002-08-27 Ondeo Nalco Company Measurement of microbiological activity in an opaque medium
JP4936637B2 (ja) * 2001-08-15 2012-05-23 ナルコ カンパニー 不透明媒質中の微生物活性の測定
AU2006238861A1 (en) * 2005-04-22 2006-11-02 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Multiple-valent opsonophagocytic assay selection panel arrays and uses therefor
US20090142796A1 (en) * 2007-12-04 2009-06-04 Becton, Dickinson And Company Detection of Inducible Resistance to Macrolide-Lincosamide-Streptogramin b
JP2010057390A (ja) * 2008-09-02 2010-03-18 Nikken Seibutsu Igaku Kenkyusho:Kk 検査用具
CN102010886B (zh) * 2010-06-02 2016-08-17 湖南省天骑医学新技术股份有限公司 结核分枝杆菌药敏试验方法及指示剂的应用及固体培养基
JP6619544B2 (ja) 2014-03-19 2019-12-11 株式会社日立ハイテクノロジーズ 検査装置
JP2017527288A (ja) * 2014-09-04 2017-09-21 セラノス, インコーポレイテッドTheranos, Inc. 病原体及び抗菌薬耐性試験
BR112018071543A2 (pt) 2016-04-22 2019-02-26 SeLux Diagnostics, Inc. execução do teste de suscetibilidade antimicrobiana e sistemas e métodos relacionados
WO2018119439A1 (en) * 2016-12-23 2018-06-28 SeLux Diagnostics, Inc. Methods for improved rapid antimicrobial susceptibility testing
WO2019237047A1 (en) * 2018-06-08 2019-12-12 SeLux Diagnostics, Inc. Antimicrobial cartridges and processes for multiplexed antimicrobial susceptibility testing
JP6636109B2 (ja) * 2018-09-11 2020-01-29 株式会社日立ハイテクノロジーズ 検査装置
GB201819187D0 (en) * 2018-11-26 2019-01-09 Univ Manchester Assay
TWI778569B (zh) 2021-04-06 2022-09-21 醫流體股份有限公司 陣列式微流體晶片及抗生素感受性測試的操作方法
CN115178309B (zh) * 2021-04-06 2024-08-09 医流体股份有限公司 阵列式微流体芯片及抗生素感受性测试的操作方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997404A (en) * 1974-06-07 1976-12-14 Johnston Laboratories, Inc. Method and apparatus for characterizing biologically active agents
US4090920A (en) * 1976-02-19 1978-05-23 Fisher Scientific Company Disposable antibiotic susceptability test package
US4385115A (en) * 1980-10-22 1983-05-24 Hoffmann-La Roche Inc. Diagnostics testing devices and processes
US4416995A (en) * 1981-09-10 1983-11-22 Bronx-Lebanon Hospital Center Method and apparatus for determining bacterial sensitivity

Also Published As

Publication number Publication date
EP0454784B2 (en) 2008-01-16
DE69026602T2 (de) 1997-01-09
EP0454784A1 (en) 1991-11-06
EP0454784B1 (en) 1996-04-17
JP3741598B2 (ja) 2006-02-01
CA2044265C (en) 2002-03-26
JP2001112498A (ja) 2001-04-24
DE69026602D1 (de) 1996-05-23
CA2044265A1 (en) 1990-07-18
DE69026602T3 (de) 2008-07-17
WO1990008196A1 (en) 1990-07-26
ES2089009T5 (es) 2008-05-16
ATE136939T1 (de) 1996-05-15
EP0454784A4 (en) 1992-09-09
JPH04502707A (ja) 1992-05-21
AU5040990A (en) 1990-08-13

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