ES2089532T3 - Dispositivo para reducir las sensaciones percibidas durante la administracion iontoforetica de farmacos. - Google Patents

Dispositivo para reducir las sensaciones percibidas durante la administracion iontoforetica de farmacos.

Info

Publication number
ES2089532T3
ES2089532T3 ES92910799T ES92910799T ES2089532T3 ES 2089532 T3 ES2089532 T3 ES 2089532T3 ES 92910799 T ES92910799 T ES 92910799T ES 92910799 T ES92910799 T ES 92910799T ES 2089532 T3 ES2089532 T3 ES 2089532T3
Authority
ES
Spain
Prior art keywords
drugs
reduce
sensation
iontophoretic administration
feelings during
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92910799T
Other languages
English (en)
Inventor
J Bradley Phipps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2089532T3 publication Critical patent/ES2089532T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBEN DISPOSITIVOS (20) PARA ADMINISTRAR AGENTES TERAPEUTICOS MEDIANTE IONTOFORESIS, CON SENSACION DISMINUIDA O MITIGADA. LOS DISPOSITIVOS ACTUAN GENERALMENTE MEDIANTE LA ADMINISTRACION DE UN AGENTE TERAPEUTICO, POR IONTOFORESIS, EN PRESENCIA DE UNA CANTIDAD DE UN ION POLIVALENTE QUE REDUCE LA SENSACION INTENCIONALMENTE AÑADIDA. IONES MULTIVALENTES PREFERENTES UTILES PARA MITIGAR LA SENSACION SON CALCIO, MAGNESIO, FOSFATO Y CINC.
ES92910799T 1991-04-02 1992-03-30 Dispositivo para reducir las sensaciones percibidas durante la administracion iontoforetica de farmacos. Expired - Lifetime ES2089532T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/679,425 US5221254A (en) 1991-04-02 1991-04-02 Method for reducing sensation in iontophoretic drug delivery

Publications (1)

Publication Number Publication Date
ES2089532T3 true ES2089532T3 (es) 1996-10-01

Family

ID=24726864

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92910799T Expired - Lifetime ES2089532T3 (es) 1991-04-02 1992-03-30 Dispositivo para reducir las sensaciones percibidas durante la administracion iontoforetica de farmacos.

Country Status (12)

Country Link
US (2) US5221254A (es)
EP (1) EP0578773B1 (es)
JP (1) JP3343348B2 (es)
AT (1) ATE140630T1 (es)
AU (1) AU1773792A (es)
DE (1) DE69212468T2 (es)
ES (1) ES2089532T3 (es)
IE (1) IE921009A1 (es)
MX (1) MX9201439A (es)
PT (1) PT100323B (es)
WO (1) WO1992017239A1 (es)
ZA (1) ZA922298B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
SG50624A1 (en) * 1991-12-30 1998-07-20 Neurex Corp Methods of producing analgesia and enhancing opiate analgesia
CA2172991A1 (en) * 1993-09-30 1995-04-06 Burton H. Sage, Jr. Iontophoretic drug delivery system and method
US5540669A (en) * 1993-09-30 1996-07-30 Becton, Dickinson And Company Iontophoretic drug delivery system and method for using same
JP3549540B2 (ja) * 1994-03-30 2004-08-04 アルザ・コーポレーション 電気的移送式投与中の皮膚刺激状態の軽減
US5498235A (en) * 1994-09-30 1996-03-12 Becton Dickinson And Company Iontophoresis assembly including patch/controller attachment
US5861439A (en) * 1994-11-14 1999-01-19 Alza Corporation Method for enhanced electrotransport agent delivery
US5611594A (en) * 1995-04-13 1997-03-18 Findlay; Robert Portable folding chair
AU3404197A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
WO1998029157A2 (en) * 1996-12-26 1998-07-09 Elan International Services Limited Device for the delivery of a substance to a subject and improved electrode assembly
US6157858A (en) * 1996-12-26 2000-12-05 Elan Pharma International Limited Device for the delivery of a substance to a subject and improved electrode assembly
US6018679A (en) 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
JP3366548B2 (ja) * 1997-02-26 2003-01-14 久光製薬株式会社 イオントフォレーシス用デバイス構造体及びその製造方法
US6119036A (en) * 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
EP0898962A1 (en) * 1997-08-28 1999-03-03 Becton, Dickinson and Company Transdermal patches and methods for inactivating skin proteases
KR100315160B1 (ko) * 1998-01-09 2002-05-13 김충섭 피부수렴제가첨가된경피투여용약제조성물
ES2279633T3 (es) * 1998-08-31 2007-08-16 Travanti Pharma Inc Sistema de liberacion controlada de farmacos.
US6475514B1 (en) * 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6421561B1 (en) 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
US7458982B2 (en) * 2002-10-04 2008-12-02 Photokinetix, Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
JP5254616B2 (ja) 2004-09-13 2013-08-07 クロノ セラピューティクス、インコーポレイテッド 生物学的同調性（ｂｉｏｓｙｎｃｈｒｏｎｏｕｓ）経皮的薬物送達
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US20070042026A1 (en) * 2005-03-17 2007-02-22 Wille John J Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions
US8372040B2 (en) 2005-05-24 2013-02-12 Chrono Therapeutics, Inc. Portable drug delivery device including a detachable and replaceable administration or dosing element
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
EP2123259A1 (en) * 2007-01-16 2009-11-25 Hokkaido University Liposome preparation for iontophoresis having antioxidant component encapsulated therein
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
JP2010187707A (ja) * 2007-06-12 2010-09-02 Hokkaido Univ インスリンを封入したイオントフォレーシス用リポソーム製剤
EP2644228A1 (en) * 2007-06-27 2013-10-02 The General Hospital Corporation Method and apparatus for optical inhibition of photodynamic therapy
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
CN103118738B (zh) * 2010-09-21 2015-06-24 皇家飞利浦电子股份有限公司 电极设备
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
WO2018035443A1 (en) * 2016-08-19 2018-02-22 University Of Cincinnati Prolonged sweat stimulation
EP3565617A1 (en) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
EP3801732A4 (en) 2018-05-29 2022-04-27 Morningside Venture Investments Limited METHODS AND SYSTEMS FOR DRUG DELIVERY
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE399044A (es) * 1933-09-09
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4211222A (en) * 1976-08-25 1980-07-08 Robert Tapper Iontophoretic burn-protection method
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
JPS56501274A (es) * 1979-10-10 1981-09-10
US4415563A (en) * 1980-04-04 1983-11-15 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclononan-2-ones
US4424210A (en) * 1980-04-04 1984-01-03 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4382529A (en) * 1980-12-15 1983-05-10 Drdlik Frank J Sanitary dispensing closure
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
KR870700024A (ko) * 1984-07-12 1987-02-28 원본미기재 약, 비타민 또는 왁진의 근육내 주사용 제제
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
DE3507301A1 (de) * 1985-03-01 1986-09-04 Arbo GmbH Medizin-Technologie, 38100 Braunschweig Bioelektrische elektrode
AU582764B2 (en) * 1985-06-10 1989-04-13 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
FR2616333A1 (fr) * 1987-06-12 1988-12-16 Cird Procede d'ionophorese pour administrer une substance dissoute ou partiellement dissoute, par voie percutanee ou perungueale et dispositif correspondant
EP0318776A1 (en) * 1987-12-04 1989-06-07 Robert Tapper Method and apparatus for minimizing skin injury with electrode use
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US4992508A (en) * 1989-06-16 1991-02-12 Imaginative Research Associates, Inc. Aqueous dispersions of polyester and polyesteramides cross-linked with metallic ions and casts made therefrom
US5167616A (en) * 1989-12-14 1992-12-01 Alza Corporation Iontophoretic delivery method
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
US5246418A (en) * 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation

Also Published As

Publication number Publication date
JP3343348B2 (ja) 2002-11-11
US5403275A (en) 1995-04-04
WO1992017239A1 (en) 1992-10-15
ZA922298B (en) 1993-01-27
DE69212468D1 (de) 1996-08-29
ATE140630T1 (de) 1996-08-15
JPH06506616A (ja) 1994-07-28
DE69212468T2 (de) 1996-12-12
MX9201439A (es) 1992-10-01
AU1773792A (en) 1992-11-02
IE921009A1 (en) 1992-10-07
EP0578773A1 (en) 1994-01-19
PT100323A (pt) 1994-04-29
EP0578773B1 (en) 1996-07-24
US5221254A (en) 1993-06-22
PT100323B (pt) 1999-04-30

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