ES2090150T3 - Nuevos compuestos de imidazol, procedimiento para su preparacion, medicamentos a base de estos compuestos, asi como algunos productos intermedios. - Google Patents

Nuevos compuestos de imidazol, procedimiento para su preparacion, medicamentos a base de estos compuestos, asi como algunos productos intermedios.

Info

Publication number
ES2090150T3
ES2090150T3 ES91101497T ES91101497T ES2090150T3 ES 2090150 T3 ES2090150 T3 ES 2090150T3 ES 91101497 T ES91101497 T ES 91101497T ES 91101497 T ES91101497 T ES 91101497T ES 2090150 T3 ES2090150 T3 ES 2090150T3
Authority
ES
Spain
Prior art keywords
compounds
procedure
intermediate products
preparation
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91101497T
Other languages
English (en)
Inventor
Rolf Dr Graeve
Ismahan Dr Okyayuz-Baklouti
Dirk Dr Seiffge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2090150T3 publication Critical patent/ES2090150T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

COMPUESTOS DE IMIDAZOL DE FORMULA I EN LA QUE R ELEVADO A 1 = ALQUILO; R (AL CUADRADO) Y R ELEVADO A 3 = H, HALOGENO O ALQUILO; X = OH O UN RESTO AMIDA CON DETERMINADOS SUSTITUYENTES. PROCEDIMIENTO PARA SU FABRICACION Y MEDICAMENTOS BASADOS EN ESTOS COMPUESTOS, ESPECIALMENTE PARA LA PROFILAXIS Y EL TRATAMIENTO DE TRASTORNOS CIRCULATORIOS, ESPECIALMENTE DE LA MICROCIRCULACION Y ENFERMEDADES DERIVADAS DE ELLO. TAMBIEN ALGUNOS PRODUCTOS INTERMEDIOS NUEVOS QUE SE UTILIZAN PARA LA FABRICACION DE COMPUESTOS DE LA FORMULA I, TALES COMO EL CLORURO DEL ACIDO 1-METIL-IMIDAZOLSULFONICO, EL DEL 1,2 -DIMETIL-IMIDAZOL-SULFONICO Y EL DEL 1-ETIL-4-IMIDAZOLSULFONICO.
ES91101497T 1990-02-10 1991-02-05 Nuevos compuestos de imidazol, procedimiento para su preparacion, medicamentos a base de estos compuestos, asi como algunos productos intermedios. Expired - Lifetime ES2090150T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4004061A DE4004061A1 (de) 1990-02-10 1990-02-10 Neue imidazolverbindungen, verfahren zu deren herstellung, arzneimittel auf basis dieser verbindungen sowie einige zwischenprodukte

Publications (1)

Publication Number Publication Date
ES2090150T3 true ES2090150T3 (es) 1996-10-16

Family

ID=6399847

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91101497T Expired - Lifetime ES2090150T3 (es) 1990-02-10 1991-02-05 Nuevos compuestos de imidazol, procedimiento para su preparacion, medicamentos a base de estos compuestos, asi como algunos productos intermedios.

Country Status (23)

Country Link
US (2) US5232922A (es)
EP (1) EP0442348B1 (es)
JP (1) JP3026847B2 (es)
KR (1) KR910015547A (es)
CN (1) CN1053919A (es)
AT (1) ATE140452T1 (es)
AU (1) AU634342B2 (es)
BR (1) BR9100520A (es)
CA (1) CA2035988A1 (es)
CS (1) CS30991A2 (es)
DE (2) DE4004061A1 (es)
DK (1) DK0442348T3 (es)
ES (1) ES2090150T3 (es)
FI (1) FI910602L (es)
GR (1) GR3020570T3 (es)
HU (1) HU207997B (es)
IE (1) IE910427A1 (es)
IL (1) IL97195A0 (es)
MX (1) MX24463A (es)
NO (1) NO910496L (es)
NZ (1) NZ237049A (es)
PT (1) PT96710A (es)
ZA (1) ZA91948B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2338930A1 (en) 1998-07-31 2000-02-10 Hamideh Zarrinmayeh Heterocyclic sulphonamide derivatives
EP1866298A2 (en) * 2005-03-31 2007-12-19 Takeda San Diego, Inc. Hydroxysteroid dehydrogenase inhibitors
BR102016023153A2 (pt) * 2016-10-04 2018-05-02 Fundação Butantan Composição, uso, e, método para tratar doenças neurodegenerativas
WO2018069237A1 (de) * 2016-10-12 2018-04-19 Basf Se Betain (b) und verfahren zu dessen herstellung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2603649A (en) * 1950-04-04 1952-07-15 American Cyanamid Co Heterocyclic sulfonamides and method of preparing the same
US3932444A (en) * 1972-04-28 1976-01-13 E. I. Du Pont De Nemours & Co. 4-Imidazolylsulfonylimidazoles
ATE35265T1 (de) * 1982-05-28 1988-07-15 Ciba Geigy Ag Neue sulfonyl(thio)harnstoffe, verfahren zu deren herstellung und deren verwendung als herbizide und/oder wachstumsregulatoren.
DE3379462D1 (de) * 1982-06-01 1989-04-27 Du Pont Herbicidal imidazole, pyrazole, thiazole and isothiazole derivatives
DE3369984D1 (en) * 1982-07-12 1987-04-09 Searle & Co 1-(1h-imidazolyl), 1-n-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them
CA1222752A (en) * 1983-05-18 1987-06-09 Beat Bohner Sulfonylureas and sulfonylthioureas, the preparation thereof, and method of use thereof as herbicides and/or growth regulators
DE3504677A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4830660A (en) * 1986-06-19 1989-05-16 Nissan Chemical Industries, Ltd. Imidazolesulfonamide derivatives and herbicides
CA1339133C (en) * 1987-03-13 1997-07-29 Rikuo Nasu Imidazole compounds and biocidal composition comprising the same for controlling harmful organisms
EP0284277A1 (en) * 1987-03-21 1988-09-28 AgrEvo UK Limited Cyanoimidazole fungicides

Also Published As

Publication number Publication date
AU7084891A (en) 1991-08-15
DE4004061A1 (de) 1991-08-14
HU207997B (en) 1993-07-28
ATE140452T1 (de) 1996-08-15
DE59107999D1 (de) 1996-08-22
PT96710A (pt) 1991-10-31
US5356922A (en) 1994-10-18
FI910602A0 (fi) 1991-02-07
US5232922A (en) 1993-08-03
EP0442348A2 (de) 1991-08-21
NO910496L (no) 1991-08-12
MX24463A (es) 1993-06-01
EP0442348B1 (de) 1996-07-17
JPH04316561A (ja) 1992-11-06
KR910015547A (ko) 1991-09-30
JP3026847B2 (ja) 2000-03-27
CA2035988A1 (en) 1991-08-11
FI910602A7 (fi) 1991-08-11
DK0442348T3 (da) 1996-11-11
FI910602L (fi) 1991-08-11
ZA91948B (en) 1991-10-30
HU910415D0 (en) 1991-08-28
HUT56549A (en) 1991-09-30
AU634342B2 (en) 1993-02-18
CN1053919A (zh) 1991-08-21
CS30991A2 (en) 1991-09-15
IL97195A0 (en) 1992-05-25
NO910496D0 (no) 1991-02-08
BR9100520A (pt) 1991-10-29
NZ237049A (en) 1992-10-28
IE910427A1 (en) 1991-08-14
GR3020570T3 (en) 1996-10-31
EP0442348A3 (en) 1992-03-04

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