ES2090465T3 - Reactivo de dextrano multivalente para su empleo en ensayos por precipitacion. - Google Patents

Reactivo de dextrano multivalente para su empleo en ensayos por precipitacion.

Info

Publication number
ES2090465T3
ES2090465T3 ES92120471T ES92120471T ES2090465T3 ES 2090465 T3 ES2090465 T3 ES 2090465T3 ES 92120471 T ES92120471 T ES 92120471T ES 92120471 T ES92120471 T ES 92120471T ES 2090465 T3 ES2090465 T3 ES 2090465T3
Authority
ES
Spain
Prior art keywords
substance
precipitation tests
multivalent
dextran reagent
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92120471T
Other languages
English (en)
Inventor
Johann Dr Karl
Josef Maier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2090465T3 publication Critical patent/ES2090465T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

EL OBJETO DE LA INVENCION ES UN REACTIVO DE DEXTRANO POLIVALENTE, PARA SU UTILIZACION EN PRUEBAS DE PRECIPITACION, PARA LA DETERMINACION DE UNA SUSTANCIA APTA PARA UNIRSE ESPECIFICAMENTE, CONSISTENTE EN DEXTRANO, EN EL QUE VARIAS MOLECULAS DE UN RECEPTOR R1, QUE ES APTO PARA UNIRSE ESPECIFICAMENTE CON LA SUSTANCIA A DETERMINAR, ESTA UNIDO A O PUEDE SER UNIDO A LA SUSTANCIA APTA PARA UNIRSE ESPECIFICAMENTE O A UN ANALOGO A ESTA SUSTANCIA.
ES92120471T 1991-12-05 1992-12-01 Reactivo de dextrano multivalente para su empleo en ensayos por precipitacion. Expired - Lifetime ES2090465T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4140142A DE4140142A1 (de) 1991-12-05 1991-12-05 Multivalentes dextranreagenz zum einsatz in praezipitationstests

Publications (1)

Publication Number Publication Date
ES2090465T3 true ES2090465T3 (es) 1996-10-16

Family

ID=6446361

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92120471T Expired - Lifetime ES2090465T3 (es) 1991-12-05 1992-12-01 Reactivo de dextrano multivalente para su empleo en ensayos por precipitacion.

Country Status (8)

Country Link
US (1) US5627078A (es)
EP (1) EP0545350B1 (es)
JP (1) JP2703163B2 (es)
AT (1) ATE140081T1 (es)
CA (1) CA2084492C (es)
DE (2) DE4140142A1 (es)
ES (1) ES2090465T3 (es)
ZA (1) ZA929417B (es)

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US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
US5929049A (en) * 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
US6271044B1 (en) * 1998-05-06 2001-08-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method and kit for detecting an analyte
US6306273B1 (en) * 1999-04-13 2001-10-23 Aclara Biosciences, Inc. Methods and compositions for conducting processes in microfluidic devices
WO2001014592A2 (en) 1999-08-25 2001-03-01 Clarity Biosciences, Inc. Identifying organisms by detecting intronic nucleic acid or encoded proteins
US9701754B1 (en) 2002-10-23 2017-07-11 City Of Hope Covalent disulfide-linked diabodies and uses thereof
US7083936B2 (en) * 2003-08-01 2006-08-01 Beckman Coulter, Inc. Aminodextran compositions and conjugates and method of making and using them
EP2674757A3 (en) * 2005-11-12 2014-03-05 Platform Diagnostics Limited Agglutination assay
CA2646329C (en) * 2006-03-20 2018-07-03 The Regents Of The University Of California Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
WO2009032949A2 (en) 2007-09-04 2009-03-12 The Regents Of The University Of California High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
CA2700410C (en) * 2007-10-03 2020-10-06 Cornell University Treatment of proliferative disorders using antibodies to psma
ES2712732T3 (es) 2009-02-17 2019-05-14 Cornell Res Foundation Inc Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
AU2010325969B2 (en) 2009-12-02 2016-10-20 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen
JP6234817B2 (ja) * 2010-09-23 2017-11-22 バイオセプト， インコーポレイテッド シグナル増幅のための方法と試薬
EP2657681A1 (en) 2012-04-26 2013-10-30 Roche Diagnostics GmbH Improvement of the sensitivity and the dynamic range of photometric assays by generating multiple calibration curves
US11254744B2 (en) 2015-08-07 2022-02-22 Imaginab, Inc. Antigen binding constructs to target molecules
US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies
WO2020068541A1 (en) * 2018-09-25 2020-04-02 Siemens Healthcare Diagnostics Inc. Methods and compositions for removing biotin interference from assays using molecular traps
CN113866406B (zh) * 2021-10-18 2022-09-27 深圳上泰生物工程有限公司 一种特异性检测糖缺失性转铁蛋白的试剂盒

Family Cites Families (28)

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NZ183970A (en) * 1976-05-03 1979-06-08 Beckman Instruments Inc Composite for use in immunoassay; derivatized polysaccharide matrix covalently coupled to an antibody by a bifunctional coupling agent; immunoassay procedure
US4615986A (en) * 1979-03-05 1986-10-07 Syntex (U.S.A.) Inc. Method for competitive protein binding assays inhibiting non-specific interference
NL8102178A (nl) * 1981-05-02 1982-12-01 Stichting Centraal Lab Werkwijze voor het aantonen van tegen bepaalde antigenen gerichte antistoffen, alsmede inrichting en reagentia voor het uitvoeren van deze werkwijze.
JPS58500874A (ja) * 1981-06-02 1983-05-26 エレクトロ−ヌ−　クレオニツクス、インコ−ポレ−テツド 免疫沈殿分析
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
US4582810A (en) * 1983-09-30 1986-04-15 Becton, Dickinson And Company Immuno-agglutination particle suspensions
US4713350A (en) * 1983-10-24 1987-12-15 Technicon Instruments Corporation Hydrophilic assay reagent containing one member of specific binding pair
US4530400A (en) * 1983-12-27 1985-07-23 Union Oil Company Of California Process for enhanced oil recovery employing synthetic sulfonates and petroleum sulfonate blends
US4749647A (en) * 1984-06-22 1988-06-07 Genetic Systems Corporation Polymerization-induced separation assay using recognition pairs
US4657853A (en) * 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
JPS6179164A (ja) * 1984-09-26 1986-04-22 Amano Pharmaceut Co Ltd 抗原抗体反応の短縮方法
US4772550A (en) * 1986-02-10 1988-09-20 Miles Inc. Heterogeneous specific binding assay employing an aggregatable binding reagent
US5057313A (en) * 1986-02-25 1991-10-15 The Center For Molecular Medicine And Immunology Diagnostic and therapeutic antibody conjugates
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
FR2601455B1 (fr) * 1986-07-11 1989-08-04 Stallergenes Lab Nouveaux reactifs biologiques en phase solide et leur procede d'obtention
US4975532A (en) * 1986-11-28 1990-12-04 Sclavo, Inc. Method to derivatize dextran
US4968742A (en) * 1987-11-09 1990-11-06 Miles Inc. Preparation of ligand-polymer conjugate having a controlled number of introduced ligands
US5268306A (en) * 1988-02-29 1993-12-07 Boehringer Mannheim Gmbh Preparation of a solid phase matrix containing a bound specific binding pair
US5180815A (en) * 1988-04-13 1993-01-19 Fuji Photo Film Co., Ltd. Modified protein for carrying hapten
US5167925A (en) * 1988-06-08 1992-12-01 North Carolina State University Precipitation of multivalent antiligands with affinity surfactants
US4925648A (en) * 1988-07-29 1990-05-15 Immunomedics, Inc. Detection and treatment of infectious and inflammatory lesions
WO1990006763A1 (en) * 1988-12-05 1990-06-28 The Trustees Of Columbia University In The City Of New York Novel derivatives of cyclosporine a, antibodies directed thereto and uses thereof
US5045480A (en) * 1989-02-09 1991-09-03 Miles Inc. Gel particles having hapten moieties bound thereto as immunoassay reagent
JP2619549B2 (ja) * 1989-06-29 1997-06-11 日本商事株式会社 抗原の定量法およびそれに用いる固相
DE4034509A1 (de) * 1990-10-30 1992-05-07 Boehringer Mannheim Gmbh Immunologisches praezipitationsverfahren zur bestimmung eines bindefaehigen analyten sowie reagenz zur durchfuehrung dieses verfahrens
US5248772A (en) * 1992-01-29 1993-09-28 Coulter Corporation Formation of colloidal metal dispersions using aminodextrans as reductants and protective agents

Also Published As

Publication number Publication date
EP0545350B1 (de) 1996-07-03
JP2703163B2 (ja) 1998-01-26
US5627078A (en) 1997-05-06
CA2084492A1 (en) 1993-06-06
EP0545350A1 (de) 1993-06-09
JPH05249117A (ja) 1993-09-28
CA2084492C (en) 2001-02-27
DE4140142A1 (de) 1993-06-09
ATE140081T1 (de) 1996-07-15
ZA929417B (en) 1994-06-06
DE59206700D1 (de) 1996-08-08

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