ES2093601T3 - Inmunoensayo de polarizacion de fluorescencia para tetrahidrocannabinoides. - Google Patents

Inmunoensayo de polarizacion de fluorescencia para tetrahidrocannabinoides.

Info

Publication number
ES2093601T3
ES2093601T3 ES88101777T ES88101777T ES2093601T3 ES 2093601 T3 ES2093601 T3 ES 2093601T3 ES 88101777 T ES88101777 T ES 88101777T ES 88101777 T ES88101777 T ES 88101777T ES 2093601 T3 ES2093601 T3 ES 2093601T3
Authority
ES
Spain
Prior art keywords
fluorescence polarization
thc
tetrahydrocannabinoids
immuno assay
polarization immuno
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88101777T
Other languages
English (en)
Inventor
Nai-Yi Wang
Robert Edward Dubler
Frank Schneider Ungemach
Roland Lawrence Walters
Susan Anne Thacker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2093601T3 publication Critical patent/ES2093601T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Liquid Crystal (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA PRESENTACION SE REFIERE A UN METODO Y REACTIVOS PARA DETERMINAR TETRAHIDROCANABINOIDES (THC) Y METABOLITOS DE THC EN UN FLUIDO BIOLOGICO TAL COMO LA ORINA. EN PARTICULAR, ESTA PRESENTACION SE REFIERE A UN PROCEDIMIENTO DE INMUNOENSAYO DE POLARIZACION DE FLUORESCENCIA PARA DETERMINAR LA PRESENCIA DE THC Y A UNA NUEVA CLASE DE COMPUESTOS MARCADORES EMPLEADOS COMO RECTIVOS EN DICHOS PROCEDIMIENTOS. EL PROCEDIMIENTO PRESENTA TAMBIEN UN NUEVO REACTIVO DE LAVADO PARA UN ENSAYO DE POLARIZACION DE FLUORESCENCIA DE THC.
ES88101777T 1987-02-17 1988-02-08 Inmunoensayo de polarizacion de fluorescencia para tetrahidrocannabinoides. Expired - Lifetime ES2093601T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1495087A 1987-02-17 1987-02-17

Publications (1)

Publication Number Publication Date
ES2093601T3 true ES2093601T3 (es) 1997-01-01

Family

ID=21768734

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101777T Expired - Lifetime ES2093601T3 (es) 1987-02-17 1988-02-08 Inmunoensayo de polarizacion de fluorescencia para tetrahidrocannabinoides.

Country Status (5)

Country Link
EP (1) EP0279308B1 (es)
JP (1) JP2812945B2 (es)
CA (1) CA1333904C (es)
DE (1) DE3855490T2 (es)
ES (1) ES2093601T3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5144030A (en) * 1987-02-17 1992-09-01 Abbott Laboratories Fluorescene polarization immunoassay for tetrahydrocannabinoids
DE69030829T2 (de) * 1989-03-10 1998-01-15 Hoffmann La Roche Reagenzien zum Nachweis von Drogen
EP0392332A3 (de) * 1989-04-12 1992-01-08 F. Hoffmann-La Roche Ag Fluoreszenzpolarisationsimmunoassay und Reagentien dafür
US5237057A (en) * 1992-04-06 1993-08-17 Biosite Diagnostics, Inc. Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
US5817766A (en) * 1995-04-05 1998-10-06 Roche Diagnostic Systems, Inc. Reagents for a cannabinoid immunoassay
CN102621297A (zh) * 2012-03-12 2012-08-01 南开大学 一种沙拉沙星的荧光偏振免疫分析检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097586A (en) 1970-06-11 1978-06-27 Biological Developments, Inc. Immunochemical assay method
US4489165A (en) * 1983-01-24 1984-12-18 Becton Dickinson And Company Chromogenic tracers for use in an assay
EP0218010A3 (en) * 1985-07-10 1988-01-07 Abbott Laboratories Ligand detection method and substituted carboxyfluorescein tracers therefor

Also Published As

Publication number Publication date
JPS63216880A (ja) 1988-09-09
DE3855490D1 (de) 1996-10-02
EP0279308A3 (en) 1990-10-17
JP2812945B2 (ja) 1998-10-22
DE3855490T2 (de) 1997-03-27
CA1333904C (en) 1995-01-10
EP0279308A2 (en) 1988-08-24
EP0279308B1 (en) 1996-08-28

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