ES2093740T3 - Formas de dosificacion solidas y estabilizadas de composiciones a base de salicilato de colina metal carboximetilcelulosa. - Google Patents

Formas de dosificacion solidas y estabilizadas de composiciones a base de salicilato de colina metal carboximetilcelulosa.

Info

Publication number
ES2093740T3
ES2093740T3 ES92110049T ES92110049T ES2093740T3 ES 2093740 T3 ES2093740 T3 ES 2093740T3 ES 92110049 T ES92110049 T ES 92110049T ES 92110049 T ES92110049 T ES 92110049T ES 2093740 T3 ES2093740 T3 ES 2093740T3
Authority
ES
Spain
Prior art keywords
salicylate
dosage forms
solid
compositions based
metal carboxymethylcellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92110049T
Other languages
English (en)
Other versions
ES2093740T4 (es
Inventor
Benjamin Oshlack
Frank C Pedi Jr
Joseph Zirlis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of ES2093740T3 publication Critical patent/ES2093740T3/es
Publication of ES2093740T4 publication Critical patent/ES2093740T4/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA ESTABILIDAD DE COMPOSICIONES DE CARBOXIMETILCELULOSA DE SALICILATO DE METAL DE SALICILATO SE MEJORA INCORPORANDO EN ELLAS UNA CELULOSA MICROCRISTALINA. LA CELULOSA MICROCRISTALINA SE ENLAZA AL RESTO DE LA COMPOSICION A BASE DE PUENTES LIQUIDOS Y SE ENCUENTRA PREFERENTEMENTE PRESENTE EN UNA CANTIDAD DE UN 2,5 A UN 25% EN PESO APROXIMADAMENTE. LA CELULOSA MICROCRISTALINA AUMENTA LA ESTABILIDAD DE LA COMPOSICION Y POR TANTO MEJORA EL ASPECTO DE LAS DOSIS SOLIDAS DE LA MISMA COMO POR EJEMPLO, PASTILLAS, CAPSULAS, SUPOSITORIOS Y GRANULOS.
ES92110049T 1991-06-17 1992-06-15 Formas de dosificacion solidas y estabilizadas de composiciones a base de salicilato de colina metal carboximetilcelulosa. Expired - Lifetime ES2093740T4 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/716,547 US5217965A (en) 1991-06-17 1991-06-17 Stabilized solid dosage forms of choline metal carboxymethylcellulose salicylate compositions

Publications (2)

Publication Number Publication Date
ES2093740T3 true ES2093740T3 (es) 1997-01-01
ES2093740T4 ES2093740T4 (es) 1997-03-16

Family

ID=24878446

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92110049T Expired - Lifetime ES2093740T4 (es) 1991-06-17 1992-06-15 Formas de dosificacion solidas y estabilizadas de composiciones a base de salicilato de colina metal carboximetilcelulosa.

Country Status (11)

Country Link
US (1) US5217965A (es)
EP (1) EP0519371B1 (es)
AT (1) ATE141795T1 (es)
AU (1) AU645205B2 (es)
CA (1) CA2071262C (es)
DE (1) DE69213113T2 (es)
DK (1) DK0519371T3 (es)
ES (1) ES2093740T4 (es)
GR (1) GR3021831T3 (es)
IE (1) IE921943A1 (es)
ZA (1) ZA924002B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US9744191B2 (en) 2012-03-19 2017-08-29 Yale University Antimicrobial compositions and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636200A (en) * 1969-06-09 1972-01-18 Hoffmann La Roche Pharmaceutical suspension
CA1070299A (en) * 1976-01-21 1980-01-22 Ernest J. Sasmor Stabilized solid form choline salicylate compositions
US4067974A (en) * 1976-01-21 1978-01-10 The Purdue Frederick Company Stabilized solid form choline salicylate compositions
US4747881A (en) * 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US5043168A (en) * 1990-04-26 1991-08-27 Sidmak Laboratories, Inc. Solid choline magnesium salicylate composition and method of preparing same

Also Published As

Publication number Publication date
DK0519371T3 (da) 1996-09-16
EP0519371B1 (en) 1996-08-28
GR3021831T3 (en) 1997-02-28
DE69213113T2 (de) 1997-03-13
ATE141795T1 (de) 1996-09-15
ES2093740T4 (es) 1997-03-16
CA2071262A1 (en) 1992-12-18
EP0519371A1 (en) 1992-12-23
DE69213113D1 (de) 1996-10-02
US5217965A (en) 1993-06-08
ZA924002B (en) 1993-02-24
IE921943A1 (en) 1992-12-30
AU645205B2 (en) 1994-01-06
CA2071262C (en) 1998-02-03
AU1730992A (en) 1992-12-24

Similar Documents

Publication Publication Date Title
SE8303531D0 (sv) Farmaceutisk komposition
KR950703952A (ko) 부분 경화된 식물성 오일이 코팅된 시메티딘 과립(Cimetidine Granules Coated with a Partially Hydrogenated Vegetable Oil)
HN1997000118A (es) 1,3, oxa thiolane nucleoside compuestos y composiciones
DE69003655D1 (de) Erythrit enthaltende kaugummizusammensetzung.
LV10954A (lv) Benzimidazola atvasinajumi to iegusanas panemiens un tos saturosa farmaceitiska kompozicija
BR8904205A (pt) Composicao de resina poliacetal resistente as intemperies
PT975348E (pt) Composicoes de tibolona estabilizadas
DK0390435T3 (da) Blanding indeholdende en forbindelse fra vitamin B gruppen, og fremstilling deraf
JPS5420126A (en) Pharmaceutical composition
ES2093740T3 (es) Formas de dosificacion solidas y estabilizadas de composiciones a base de salicilato de colina metal carboximetilcelulosa.
ATE23438T1 (de) Neue arzneimittelpraeparation fuer glykosidhydrolasen-inhibitoren.
ATE166588T1 (de) Quellmittelzusammensetzung
GB1525971A (en) Deodorant composition
JPS5318655A (en) Chlorine-containing resin composition
SE8704240L (sv) Analgetiska preparat
ES2110538T3 (es) Masa de moldeo termoplastica a base de betun.
JPS5324032A (en) Sublimable composition
JPS552645A (en) Material for solid ointment
SE7409378L (es)
JPS53133240A (en) Fluorescent coating composition
JPS5397044A (en) Stabilized synthetic resin composition
JPS5335752A (en) Halonge-containing resin composition indluding weak-smelling stalilizer
JPS5293406A (en) Grease composition
JPS53143647A (en) Hologen-containing resin composition
JPS54125205A (en) Coal-heavy oil mixture fuel composition

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 519371

Country of ref document: ES