ES2093965T3 - Dispositivo tipo reactor de volumen variable y procedimiento de cultivo de material celular. - Google Patents

Dispositivo tipo reactor de volumen variable y procedimiento de cultivo de material celular.

Info

Publication number
ES2093965T3
ES2093965T3 ES93910090T ES93910090T ES2093965T3 ES 2093965 T3 ES2093965 T3 ES 2093965T3 ES 93910090 T ES93910090 T ES 93910090T ES 93910090 T ES93910090 T ES 93910090T ES 2093965 T3 ES2093965 T3 ES 2093965T3
Authority
ES
Spain
Prior art keywords
variable volume
reactor type
type device
cell material
enclosure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93910090T
Other languages
English (en)
Inventor
Michel Boulay
Alain Deloire
Marie-Claude Mauro
Alain Meybeck
Guy Pierre
Jean-No L Rabaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LVMH Recherche GIE
Original Assignee
LVMH Recherche GIE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LVMH Recherche GIE filed Critical LVMH Recherche GIE
Application granted granted Critical
Publication of ES2093965T3 publication Critical patent/ES2093965T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26—Conditioning fluids entering or exiting the reaction vessel

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

DISPOSITIVO DEL TIPO REACTOR DESTINADO A PONER EN CONTACTO PARTICULAS SOLIDAS CON UN LIQUIDO. EL DISPOSITIVO COMPRENDE: UN RECINTO (5) DELIMITADO POR PAREDES, DESTINADO A LLENARSE DE DICHO LIQUIDO Y A CONTENER DICHAS PARTICULAS SOLIDAS EN CONTACTO CON EL LIQUIDO, MEDIOS DE ALIMENTACION DE EVACUACION DEL LIQUIDO (3A,3B) DEL RECINTO, CARACTERIZADO PORQUE AL MENOS UNA DE DICHAS PAREDES (1) DEL RECINTO PUEDE MOVERSE DE MODO QUE EL RECINTO TIENE UN VOLUMEN VARIABLE. EL PRESENTE INVENTO SE REFIERE ASIMISMO A PROCEDIMIENTOS DE REACCION O CULTIVO CON AYUDA DEL DISPOSITIVO.
ES93910090T 1992-05-06 1993-05-06 Dispositivo tipo reactor de volumen variable y procedimiento de cultivo de material celular. Expired - Lifetime ES2093965T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9205579A FR2690926B1 (fr) 1992-05-06 1992-05-06 Dispositif du type reacteur a volume variable et procede de culture cellulaire.

Publications (1)

Publication Number Publication Date
ES2093965T3 true ES2093965T3 (es) 1997-01-01

Family

ID=9429586

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93910090T Expired - Lifetime ES2093965T3 (es) 1992-05-06 1993-05-06 Dispositivo tipo reactor de volumen variable y procedimiento de cultivo de material celular.

Country Status (9)

Country Link
US (1) US5707868A (es)
EP (1) EP0640124B1 (es)
JP (1) JPH07506250A (es)
AU (1) AU4074193A (es)
CA (1) CA2135184A1 (es)
DE (1) DE69305163T2 (es)
ES (1) ES2093965T3 (es)
FR (1) FR2690926B1 (es)
WO (1) WO1993022420A1 (es)

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WO1998029730A1 (en) * 1996-12-31 1998-07-09 Rorer Pharmaceutical Products Inc. Method and apparatus for selective depletion of biological particles
US6168944B1 (en) * 1997-01-31 2001-01-02 Schering Corporation Methods for cultivating cells and propagating viruses
US6146891A (en) 1997-01-31 2000-11-14 Schering Corporation Methods for cultivating cells and propagating viruses
US6290910B1 (en) * 1999-03-03 2001-09-18 University Of North Florida Continuously variable volume chamber for flow injection analysis
DE19920811B4 (de) * 1999-05-06 2004-08-19 Micronas Gmbh Vorrichtung zur Durchführung von Untersuchungen an Zellkulturen
US7795012B2 (en) 1999-05-06 2010-09-14 Micronas Gmbh Device for performing analysis on cell cultures
FR2803852B1 (fr) 2000-01-17 2004-11-05 Farzin Sarem Dispositif de culture cellulaire et tissulaire a circulation de fluide de culture controlee
CA2458941A1 (en) * 2001-08-30 2003-03-13 Arbomedics Gmbh Method and device for the in vitro cultivation of cells
EP1465979A4 (en) * 2001-12-21 2007-11-14 Organogenesis Inc CHAMBER WITH ADJUSTABLE VOLUME FOR CELL CULTURE AND ORGAN SUPPORT
CN1300297C (zh) * 2002-09-20 2007-02-14 华东理工大学 一种用于动物细胞扩大接种的消化反应器
DE10322054B4 (de) * 2003-05-15 2015-06-18 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur Kultivierung von Zellen
US7455814B2 (en) * 2004-04-23 2008-11-25 Giblin Leonard J Metered dispenser and aspirator device
DE102004024833A1 (de) * 2004-05-19 2005-12-29 Universität Rostock Vorrichtung zur Regelung des Füllstands von Medium in einem Kulturgefäß
TWI302569B (en) * 2004-12-31 2008-11-01 Ind Tech Res Inst Bioreactor system
US8372632B2 (en) * 2006-06-14 2013-02-12 Malcolm Glen Kertz Method and apparatus for CO2 sequestration
US8415142B2 (en) * 2006-06-14 2013-04-09 Malcolm Glen Kertz Method and apparatus for CO2 sequestration
WO2008089510A1 (en) * 2007-01-22 2008-07-31 Ian Malcolm Wright A variable volume bioreactor
GB2450761B (en) * 2007-07-06 2010-08-04 Univ London Multi-functional chamber for housing a biological component
KR101061424B1 (ko) 2009-07-15 2011-09-01 수성건설 주식회사 미생물 배양장치
AU2011250989B2 (en) * 2010-05-12 2015-05-07 Scinus Cell Expansion B.V. Cell-culture-bag
JP5922373B2 (ja) * 2011-10-31 2016-05-24 日機装株式会社 血液吸着器の製造方法及び製造装置
WO2014074772A1 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Mixotrophic, phototrophic, and heterotrophic combination methods and systems
WO2014074770A2 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Balanced mixotrophy methods
SG11201504219QA (en) * 2012-12-11 2015-06-29 Pall Technology Uk Ltd Recipient for cell cultivation
FR3000743B1 (fr) 2013-01-07 2016-02-05 Arkema France Procede de metathese croisee
ES2911309T3 (es) * 2014-04-28 2022-05-18 Fraunhofer Ges Forschung Sistemas de fermentación
JP6457338B2 (ja) * 2015-05-28 2019-01-23 株式会社日立製作所 液体還流容器、細胞濃縮装置及び細胞濃縮システム
JP6268342B2 (ja) * 2016-04-27 2018-01-31 株式会社ジェイテックコーポレーション 大量細胞培養システム及びそれに用いる回転細胞培養装置
US12344829B2 (en) * 2016-10-28 2025-07-01 Global Life Sciences Solutions Usa Llc Bioreactor tray
GB201811402D0 (en) * 2018-07-12 2018-08-29 Alconbury Weston Ltd Liquid process assembly
TWI732357B (zh) * 2018-12-27 2021-07-01 財團法人工業技術研究院 細胞培養裝置及方法
CN121925475A (zh) * 2023-09-29 2026-04-24 康宁股份有限公司 组合式悬浮和贴壁细胞生物反应器系统及相关方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3027305A (en) * 1959-01-16 1962-03-27 Robert R Freeman Apparatus for the cultivation of microorganisms
DE1517814B2 (de) * 1966-09-02 1976-11-18 Intermag Getränke-Technik AG, Aarau (Schweiz) Verfahren und vorrichtung zur kontinuierlichen behandlung von fluessigkeiten mit enzymproduzierenden mikroorganismen
DE2514638A1 (de) * 1975-04-03 1976-10-14 Fresenius Inst Verfahren und vorrichtung zur durchfuehrung enzymkatalysierter redoxreaktionen
SU544676A1 (ru) * 1975-07-15 1977-01-30 Проточна камера дл культивировани биообъектов
US4286061A (en) * 1978-09-05 1981-08-25 Corning Glass Works Method for continuous culturing of microbes
FR2507496A1 (fr) * 1981-06-12 1982-12-17 Dumont Engineering Et Cie Sa Appareil destine notamment a l'hydrolyse et a la filtration ainsi que ses utilisations
FR2519651A1 (fr) * 1982-01-14 1983-07-18 Milois Jean Fermenteur petit modele de production de gaz vegetal pour fumiers et matieres analogues
DE3327541A1 (de) * 1983-07-30 1985-02-14 Wilhelm 4284 Heiden Wissusek Verfahren und vorrichtung zur gewinnung von biogas
JPH0697991B2 (ja) * 1986-07-31 1994-12-07 エイブル株式会社 多孔性素材を用いる化学反応方法及び装置
JPS63133978A (ja) * 1986-11-26 1988-06-06 Rikagaku Kenkyusho 細胞培養装置
JPH0697985B2 (ja) * 1987-12-28 1994-12-07 雪印乳業株式会社 流動槽付反応器
JPH0695929B2 (ja) * 1988-05-25 1994-11-30 日本碍子株式会社 酵素固定化バイオリアクター
US5260211A (en) * 1989-12-07 1993-11-09 Snow Brand Milk Products Co., Ltd. Process for cultivating adhesive cells in a packed bed of solid cell matrix
DE4027290C2 (de) * 1990-08-29 1995-03-23 Forschungszentrum Juelich Gmbh Verfahren zur Gewinnung von Enzymen aus enzymhaltigen Suspensionen

Also Published As

Publication number Publication date
DE69305163D1 (de) 1996-11-07
AU4074193A (en) 1993-11-29
JPH07506250A (ja) 1995-07-13
DE69305163T2 (de) 1997-04-03
EP0640124B1 (fr) 1996-10-02
FR2690926B1 (fr) 1995-08-04
CA2135184A1 (fr) 1993-11-11
WO1993022420A1 (fr) 1993-11-11
FR2690926A1 (fr) 1993-11-12
EP0640124A1 (fr) 1995-03-01
US5707868A (en) 1998-01-13

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