ES2095658T3 - Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion. - Google Patents
Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion.Info
- Publication number
- ES2095658T3 ES2095658T3 ES93916292T ES93916292T ES2095658T3 ES 2095658 T3 ES2095658 T3 ES 2095658T3 ES 93916292 T ES93916292 T ES 93916292T ES 93916292 T ES93916292 T ES 93916292T ES 2095658 T3 ES2095658 T3 ES 2095658T3
- Authority
- ES
- Spain
- Prior art keywords
- active substance
- composition
- pct
- preparation
- controlled release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title abstract 6
- 238000013270 controlled release Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229920000310 Alpha glucan Polymers 0.000 abstract 1
- 229920000856 Amylose Polymers 0.000 abstract 1
- 229920001503 Glucan Polymers 0.000 abstract 1
- GUBGYTABKSRVRQ-ASMJPISFSA-N alpha-maltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-ASMJPISFSA-N 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
UNA COMPOSICION PARA LA LIBERACION RETARDADA DE UNA SUSTANCIA ACTIVA, TAL COMO UN MEDICAMENTO, EN DONDE LA SUSTANCIA ACTIVA SE ENCUENTRA INCORPORADA EN UNA MATRIZ POLISACARIDA FORMADA POR UN GLUCANO DE CADENA RECTA ESENCIALMENTE CRISTALINO, EN PARTICULAR UN (ALFA)-GLUCANO QUE TIENE UNA ESTRUCTURA HELICOIDAL, TAL COMO UNA AMILODEXTRINA O UNA TRACCION QUE TIENE UNA ESTRUCTURA HELICOIDAL OBTENIDA DE UNA AMILOSA V. LA COMPOSICION PUEDE CONTENER UNA CIERTA CANTIDAD DE UNA SUSTANCIA ACTIVA DE ENTRE UN 1,0 Y UN 80% EN PESO Y LA SUSTANCIA ACTIVA PUEDE TENER, DEPENDIENDO DE LA HIDROFILICIDAD, UN PESO MOLECULAR DE HASTA 500 O 1500 DALTONS. LA SUSTANCIA ACTIVA SE LIBERA DE LA COMPOSICION A UNA VELOCIDAD CONSTANTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9201195A NL9201195A (nl) | 1992-07-03 | 1992-07-03 | Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2095658T3 true ES2095658T3 (es) | 1997-02-16 |
Family
ID=19861014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93916292T Expired - Lifetime ES2095658T3 (es) | 1992-07-03 | 1993-07-02 | Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5585114A (es) |
| EP (1) | EP0648116B1 (es) |
| JP (1) | JPH07508533A (es) |
| AT (1) | ATE143801T1 (es) |
| AU (1) | AU678166B2 (es) |
| CA (1) | CA2139494A1 (es) |
| DE (1) | DE69305346T2 (es) |
| DK (1) | DK0648116T3 (es) |
| ES (1) | ES2095658T3 (es) |
| GR (1) | GR3022195T3 (es) |
| NL (1) | NL9201195A (es) |
| WO (1) | WO1994001092A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL9401572A (nl) * | 1994-09-27 | 1996-05-01 | Avebe Coop Verkoop Prod | Zetmeelprodukten als tabletteerhulpstof, werkwijze voor het bereiden daarvan alsmede werkwijze voor het maken van tabletten. |
| FR2743496B1 (fr) * | 1996-01-15 | 1998-04-10 | Univ Rennes | Composite macroporeux support de substance(s) medicamenteuse(s) utilisable comme materiau de reconstitution osseuse et procede d'elaboration |
| GB9605857D0 (en) * | 1996-03-20 | 1996-05-22 | Tester Richard F | Polysaccharides as chemical release systems |
| US5879707A (en) * | 1996-10-30 | 1999-03-09 | Universite De Montreal | Substituted amylose as a matrix for sustained drug release |
| CA2211778A1 (en) * | 1997-08-14 | 1999-02-14 | Francois Carriere | Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents |
| WO1999030691A2 (en) * | 1997-12-18 | 1999-06-24 | Ato B.V. | Composition for the controlled release of active compounds |
| EA008224B1 (ru) | 2001-03-13 | 2007-04-27 | Пенвест Фармасьютикалз Ко. | Хронотерапевтические дозированные формы |
| JP3742335B2 (ja) * | 2001-12-20 | 2006-02-01 | 富士通株式会社 | 入出力バッファ回路 |
| US7081261B2 (en) * | 2002-05-14 | 2006-07-25 | National Starch And Chemical Investment Holding Corporation | Resistant starch prepared by isoamylase debranching of low amylose starch |
| US6890571B2 (en) * | 2002-05-14 | 2005-05-10 | National Starch And Chemical Investment Holding Corporation | Slowly digestible starch product |
| US6929817B2 (en) * | 2002-05-14 | 2005-08-16 | National Starch & Chemical Investment Holding Corporation | Slowly digestible starch product |
| US20040185097A1 (en) * | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
| JP4959191B2 (ja) | 2003-07-11 | 2012-06-20 | 旭化成ケミカルズ株式会社 | 機能性澱粉粉末 |
| US20070071810A1 (en) * | 2003-08-26 | 2007-03-29 | Kenichi Kudo | Additive for tablets |
| EA200600598A1 (ru) | 2003-09-19 | 2006-08-25 | Пенвест Фармасьютикалз Ко. | Лекарственные формы замедленного высвобождения |
| BRPI0520734A2 (pt) | 2005-12-09 | 2009-05-26 | Sca Hygiene Prod Ab | produto absorvente |
| RU2519715C2 (ru) * | 2008-10-23 | 2014-06-20 | Хенкель Корпорейшн | Фармацевтические гранулы, содержащие модифицированный крахмал, и их терапевтические применения |
| US20130172411A1 (en) * | 2010-03-22 | 2013-07-04 | Cadila Healthcare Limited | Stable pharmaceutical compositions comprising fesoterodine |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3493652A (en) * | 1962-09-14 | 1970-02-03 | Charles W Hartman | Controlled release medicament |
| GB1072795A (en) * | 1963-08-28 | 1967-06-21 | Eastman Kodak Co | Solid composition containing fat-soluble vitamins and processes for making it |
| US3490742A (en) * | 1966-01-14 | 1970-01-20 | Staley Mfg Co A E | Compressed tablets |
| EP0169893A4 (en) * | 1984-01-31 | 1987-01-22 | Scm Corp | CAPSULE MATRIX COMPOSITION AND THIS INCLUDED ENCODED PRODUCT. |
| IT1191674B (it) * | 1986-03-07 | 1988-03-23 | Eurand Spa | Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale |
| JPH0747539B2 (ja) * | 1986-10-22 | 1995-05-24 | 東京田辺製薬株式会社 | 胆汁酸固形製剤 |
| DE3721574A1 (de) * | 1987-06-30 | 1989-01-12 | Kettelhack Riker Pharma Gmbh | Arzneimittel in form von pellets mit enzymatisch kontrollierter arzneistoff-freisetzung |
| GB8812490D0 (en) * | 1988-05-26 | 1988-06-29 | Agricultural & Food Res | Delayed release formulations |
| CA2041774C (en) * | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Use of cross-linked amylose as a matrix for the slow release of biologically active compounds |
-
1992
- 1992-07-03 NL NL9201195A patent/NL9201195A/nl not_active Application Discontinuation
-
1993
- 1993-07-02 DE DE69305346T patent/DE69305346T2/de not_active Expired - Fee Related
- 1993-07-02 CA CA002139494A patent/CA2139494A1/en not_active Abandoned
- 1993-07-02 WO PCT/NL1993/000140 patent/WO1994001092A1/en not_active Ceased
- 1993-07-02 US US08/356,256 patent/US5585114A/en not_active Expired - Fee Related
- 1993-07-02 DK DK93916292.1T patent/DK0648116T3/da active
- 1993-07-02 AT AT93916292T patent/ATE143801T1/de not_active IP Right Cessation
- 1993-07-02 EP EP93916292A patent/EP0648116B1/en not_active Expired - Lifetime
- 1993-07-02 JP JP6503185A patent/JPH07508533A/ja active Pending
- 1993-07-02 AU AU45893/93A patent/AU678166B2/en not_active Ceased
- 1993-07-02 ES ES93916292T patent/ES2095658T3/es not_active Expired - Lifetime
-
1996
- 1996-12-30 GR GR960403674T patent/GR3022195T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL9201195A (nl) | 1994-02-01 |
| JPH07508533A (ja) | 1995-09-21 |
| CA2139494A1 (en) | 1994-01-20 |
| WO1994001092A1 (en) | 1994-01-20 |
| DE69305346D1 (de) | 1996-11-14 |
| AU678166B2 (en) | 1997-05-22 |
| DK0648116T3 (da) | 1997-03-24 |
| US5585114A (en) | 1996-12-17 |
| ATE143801T1 (de) | 1996-10-15 |
| EP0648116B1 (en) | 1996-10-09 |
| GR3022195T3 (en) | 1997-03-31 |
| AU4589393A (en) | 1994-01-31 |
| DE69305346T2 (de) | 1997-04-30 |
| EP0648116A1 (en) | 1995-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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