ES2095658T3 - Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion. - Google Patents

Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion.

Info

Publication number
ES2095658T3
ES2095658T3 ES93916292T ES93916292T ES2095658T3 ES 2095658 T3 ES2095658 T3 ES 2095658T3 ES 93916292 T ES93916292 T ES 93916292T ES 93916292 T ES93916292 T ES 93916292T ES 2095658 T3 ES2095658 T3 ES 2095658T3
Authority
ES
Spain
Prior art keywords
active substance
composition
pct
preparation
controlled release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93916292T
Other languages
English (en)
Inventor
Arie Cornelis Besemer
Coenraad Ferdinand Lerk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Application granted granted Critical
Publication of ES2095658T3 publication Critical patent/ES2095658T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

UNA COMPOSICION PARA LA LIBERACION RETARDADA DE UNA SUSTANCIA ACTIVA, TAL COMO UN MEDICAMENTO, EN DONDE LA SUSTANCIA ACTIVA SE ENCUENTRA INCORPORADA EN UNA MATRIZ POLISACARIDA FORMADA POR UN GLUCANO DE CADENA RECTA ESENCIALMENTE CRISTALINO, EN PARTICULAR UN (ALFA)-GLUCANO QUE TIENE UNA ESTRUCTURA HELICOIDAL, TAL COMO UNA AMILODEXTRINA O UNA TRACCION QUE TIENE UNA ESTRUCTURA HELICOIDAL OBTENIDA DE UNA AMILOSA V. LA COMPOSICION PUEDE CONTENER UNA CIERTA CANTIDAD DE UNA SUSTANCIA ACTIVA DE ENTRE UN 1,0 Y UN 80% EN PESO Y LA SUSTANCIA ACTIVA PUEDE TENER, DEPENDIENDO DE LA HIDROFILICIDAD, UN PESO MOLECULAR DE HASTA 500 O 1500 DALTONS. LA SUSTANCIA ACTIVA SE LIBERA DE LA COMPOSICION A UNA VELOCIDAD CONSTANTE.
ES93916292T 1992-07-03 1993-07-02 Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion. Expired - Lifetime ES2095658T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9201195A NL9201195A (nl) 1992-07-03 1992-07-03 Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat.

Publications (1)

Publication Number Publication Date
ES2095658T3 true ES2095658T3 (es) 1997-02-16

Family

ID=19861014

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93916292T Expired - Lifetime ES2095658T3 (es) 1992-07-03 1993-07-02 Composicion para la liberacion controlada de una substancia activa y metodo para la preparacion de tal composicion.

Country Status (12)

Country Link
US (1) US5585114A (es)
EP (1) EP0648116B1 (es)
JP (1) JPH07508533A (es)
AT (1) ATE143801T1 (es)
AU (1) AU678166B2 (es)
CA (1) CA2139494A1 (es)
DE (1) DE69305346T2 (es)
DK (1) DK0648116T3 (es)
ES (1) ES2095658T3 (es)
GR (1) GR3022195T3 (es)
NL (1) NL9201195A (es)
WO (1) WO1994001092A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9401572A (nl) * 1994-09-27 1996-05-01 Avebe Coop Verkoop Prod Zetmeelprodukten als tabletteerhulpstof, werkwijze voor het bereiden daarvan alsmede werkwijze voor het maken van tabletten.
FR2743496B1 (fr) * 1996-01-15 1998-04-10 Univ Rennes Composite macroporeux support de substance(s) medicamenteuse(s) utilisable comme materiau de reconstitution osseuse et procede d'elaboration
GB9605857D0 (en) * 1996-03-20 1996-05-22 Tester Richard F Polysaccharides as chemical release systems
US5879707A (en) * 1996-10-30 1999-03-09 Universite De Montreal Substituted amylose as a matrix for sustained drug release
CA2211778A1 (en) * 1997-08-14 1999-02-14 Francois Carriere Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents
WO1999030691A2 (en) * 1997-12-18 1999-06-24 Ato B.V. Composition for the controlled release of active compounds
AP1748A (en) 2001-03-13 2007-06-11 Penwest Pharmaceuticals Co Chronotherapeutic dosage forms.
JP3742335B2 (ja) * 2001-12-20 2006-02-01 富士通株式会社 入出力バッファ回路
US7081261B2 (en) * 2002-05-14 2006-07-25 National Starch And Chemical Investment Holding Corporation Resistant starch prepared by isoamylase debranching of low amylose starch
US6929817B2 (en) * 2002-05-14 2005-08-16 National Starch & Chemical Investment Holding Corporation Slowly digestible starch product
US6890571B2 (en) * 2002-05-14 2005-05-10 National Starch And Chemical Investment Holding Corporation Slowly digestible starch product
US20040185097A1 (en) * 2003-01-31 2004-09-23 Glenmark Pharmaceuticals Ltd. Controlled release modifying complex and pharmaceutical compositions thereof
US9101155B2 (en) 2003-07-11 2015-08-11 Asahi Kasei Chemicals Corporation Functional starch powder
US20070071810A1 (en) * 2003-08-26 2007-03-29 Kenichi Kudo Additive for tablets
US8389008B2 (en) 2003-09-19 2013-03-05 Penwest Pharmaceuticals Co. Delayed release dosage forms
KR101377553B1 (ko) 2005-12-09 2014-03-25 에스체아 히기에너 프로덕츠 악티에볼라그 흡수 제품
WO2010048389A2 (en) * 2008-10-23 2010-04-29 Henkel Corporation Pharmaceutical pellets comprising modified starch and therapeutic applications therefor
US20130172411A1 (en) * 2010-03-22 2013-07-04 Cadila Healthcare Limited Stable pharmaceutical compositions comprising fesoterodine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3493652A (en) * 1962-09-14 1970-02-03 Charles W Hartman Controlled release medicament
GB1072795A (en) * 1963-08-28 1967-06-21 Eastman Kodak Co Solid composition containing fat-soluble vitamins and processes for making it
US3490742A (en) * 1966-01-14 1970-01-20 Staley Mfg Co A E Compressed tablets
EP0169893A4 (en) * 1984-01-31 1987-01-22 Scm Corp CAPSULE MATRIX COMPOSITION AND THIS INCLUDED ENCODED PRODUCT.
IT1191674B (it) * 1986-03-07 1988-03-23 Eurand Spa Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale
JPH0747539B2 (ja) * 1986-10-22 1995-05-24 東京田辺製薬株式会社 胆汁酸固形製剤
DE3721574A1 (de) * 1987-06-30 1989-01-12 Kettelhack Riker Pharma Gmbh Arzneimittel in form von pellets mit enzymatisch kontrollierter arzneistoff-freisetzung
GB8812490D0 (en) * 1988-05-26 1988-06-29 Agricultural & Food Res Delayed release formulations
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds

Also Published As

Publication number Publication date
GR3022195T3 (en) 1997-03-31
AU4589393A (en) 1994-01-31
JPH07508533A (ja) 1995-09-21
EP0648116A1 (en) 1995-04-19
CA2139494A1 (en) 1994-01-20
DE69305346D1 (de) 1996-11-14
AU678166B2 (en) 1997-05-22
ATE143801T1 (de) 1996-10-15
DE69305346T2 (de) 1997-04-30
EP0648116B1 (en) 1996-10-09
US5585114A (en) 1996-12-17
DK0648116T3 (da) 1997-03-24
NL9201195A (nl) 1994-02-01
WO1994001092A1 (en) 1994-01-20

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