ES2095843T3 - Conversion fotoquimica de cefalosporinas, 1-carba(destia)cefalosporinas y 1-oxa(1-destia)cefalosporinas. - Google Patents

Conversion fotoquimica de cefalosporinas, 1-carba(destia)cefalosporinas y 1-oxa(1-destia)cefalosporinas.

Info

Publication number
ES2095843T3
ES2095843T3 ES89312828T ES89312828T ES2095843T3 ES 2095843 T3 ES2095843 T3 ES 2095843T3 ES 89312828 T ES89312828 T ES 89312828T ES 89312828 T ES89312828 T ES 89312828T ES 2095843 T3 ES2095843 T3 ES 2095843T3
Authority
ES
Spain
Prior art keywords
cephalosporins
destia
carba
oxa
dethia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89312828T
Other languages
English (en)
Inventor
Larry Wayne Hertel
John Michael Morin Jr
Robert Theodore Vasileff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2095843T3 publication Critical patent/ES2095843T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
    • B01J19/122—Incoherent waves
    • B01J19/123—Ultraviolet light
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D463/08—Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Electromagnetism (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

UN PROCESO PARA LA CONVERSION FOTOQUIMICA DE 3-EXOMETILENO CEFAMS (O 1-CABA(1-DETIA) CEFAMS O 1-OXA(1DETIA)CEFAMS) DEL CORRESPONDIENTE 3-ALQUIL-3-CEFEM (O 1CARBA (1 DETIA) CEFEM O 1-OXA (1-DETIA)-CEFEM) ES PROVISTO. TAMBIEN SON PROVISTOS 3-CEFAMS UTILES COMO INTERMEDIARIOS DE LOS COMPUESTOS 3-CEFEMS.
ES89312828T 1989-03-15 1989-12-08 Conversion fotoquimica de cefalosporinas, 1-carba(destia)cefalosporinas y 1-oxa(1-destia)cefalosporinas. Expired - Lifetime ES2095843T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,169 US4888100A (en) 1989-03-15 1989-03-15 Photochemical conversion of cephalosporins, 1-carba(1-dethia)cephalosporins and 1-oxa(1-dethia)cephalosporins

Publications (1)

Publication Number Publication Date
ES2095843T3 true ES2095843T3 (es) 1997-03-01

Family

ID=23262398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89312828T Expired - Lifetime ES2095843T3 (es) 1989-03-15 1989-12-08 Conversion fotoquimica de cefalosporinas, 1-carba(destia)cefalosporinas y 1-oxa(1-destia)cefalosporinas.

Country Status (12)

Country Link
US (1) US4888100A (es)
EP (1) EP0387448B1 (es)
JP (1) JPH02268188A (es)
KR (1) KR900014402A (es)
AT (1) ATE147389T1 (es)
CA (1) CA2005166A1 (es)
DE (1) DE68927636T2 (es)
ES (1) ES2095843T3 (es)
GR (1) GR3022830T3 (es)
HU (1) HU206360B (es)
IL (1) IL92623A (es)
MX (1) MX18633A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60187689A (ja) * 1984-03-06 1985-09-25 Otsuka Chem Co Ltd ３−エキソメチレンセフアム誘導体の製造法

Also Published As

Publication number Publication date
DE68927636D1 (de) 1997-02-20
IL92623A (en) 1994-07-31
EP0387448A2 (en) 1990-09-19
DE68927636T2 (de) 1997-05-28
EP0387448A3 (en) 1992-01-22
MX18633A (es) 1993-11-01
CA2005166A1 (en) 1990-09-15
US4888100A (en) 1989-12-19
IL92623A0 (en) 1990-08-31
JPH02268188A (ja) 1990-11-01
ATE147389T1 (de) 1997-01-15
HU206360B (en) 1992-10-28
GR3022830T3 (en) 1997-06-30
HUT53647A (en) 1990-11-28
KR900014402A (ko) 1990-10-23
EP0387448B1 (en) 1997-01-08
HU896486D0 (en) 1990-02-28

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