ES2095852T3 - Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c. - Google Patents

Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Info

Publication number
ES2095852T3
ES2095852T3 ES90124241T ES90124241T ES2095852T3 ES 2095852 T3 ES2095852 T3 ES 2095852T3 ES 90124241 T ES90124241 T ES 90124241T ES 90124241 T ES90124241 T ES 90124241T ES 2095852 T3 ES2095852 T3 ES 2095852T3
Authority
ES
Spain
Prior art keywords
detection
hcv
hepatitis
virus
antibodies against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90124241T
Other languages
English (en)
Inventor
Robert J Deleys
Dirk Pollet
Geert Maertens
Heuverswyn Hugo Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26125651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2095852(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Application granted granted Critical
Publication of ES2095852T3 publication Critical patent/ES2095852T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

ESTA INVENCION SE REFIERE A UNAS SECUENCIAS PEPTIDAS QUE TIENEN LAS SECUENCIAS DE AMINOACIDOS DADAS EN EL LISTADO DE SECUENCIAS (SECUENCIA ID NO. 1 AL 20), QUE SON CAPACES DE MIMICICAR LAS PROTEINAS CODIFICADAS POR HCV PARA SU UTILIZACION COMO REACTIVOS PARA EL FILTRADO DE LA SANGRE Y PRODUCTOS SANGUINEOS PARA SU EXPOSICION ANTERIOR AL HCV. LOS PEPTIDOS TIENEN AL MENOS 5 AMINOACIDOS DE LONGITUD Y PUEDEN SER UTILIZADOS EN DISTINTOS ENSAYOS ESPECIFICOS PARA LA DETECCION DE ANTICUERPOS DE HCV, PARA LA DETECCION DE ANTIGENOS HCV O COMO INMUNOGENOS.
ES90124241T 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c. Expired - Lifetime ES2095852T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG1996005024A SG47062A1 (en) 1990-12-14 1990-12-14 Synthetic antigens for the detection of antibodies to hepatitis virus
EP90124241A EP0489968B1 (en) 1990-12-14 1990-12-14 Synthetic antigens for the detection of antibodies to hepatitis C virus

Publications (1)

Publication Number Publication Date
ES2095852T3 true ES2095852T3 (es) 1997-03-01

Family

ID=26125651

Family Applications (3)

Application Number Title Priority Date Filing Date
ES96201157T Expired - Lifetime ES2138784T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
ES90124241T Expired - Lifetime ES2095852T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
ES94108611T Expired - Lifetime ES2101388T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES96201157T Expired - Lifetime ES2138784T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES94108611T Expired - Lifetime ES2101388T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.

Country Status (18)

Country Link
US (1) US5922532A (es)
EP (3) EP0754704B1 (es)
JP (1) JP2995216B2 (es)
KR (3) KR0181344B1 (es)
AT (3) ATE185350T1 (es)
AU (1) AU652013B2 (es)
BR (1) BR9106220A (es)
CY (2) CY2043A (es)
DE (2) DE69029092T2 (es)
DK (3) DK0489968T3 (es)
ES (3) ES2138784T3 (es)
GR (3) GR3022089T3 (es)
HK (1) HK57597A (es)
HU (1) HU218357B (es)
IL (1) IL100158A (es)
NZ (1) NZ240964A (es)
SG (1) SG47062A1 (es)
WO (1) WO1992010514A2 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
ATE206717T1 (de) * 1990-11-03 2001-10-15 Dade Behring Marburg Gmbh Hcv-spezifische peptide, mittel dazu und ihre verwendung
US5910404A (en) * 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
WO1992012992A2 (en) * 1991-01-14 1992-08-06 James N. Gamble Institute Of Medical Research Basic structural immunogenic polypeptides having epitopes for hcv, antibodies, polynucleotide sequences, vaccines and methods
WO1993000365A2 (en) * 1991-06-24 1993-01-07 Chiron Corporation Hepatitis c virus (hcv) polypeptides
DE4209215A1 (de) 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
US5811246A (en) * 1991-12-17 1998-09-22 The Research Foundation Of State University Of New York Process for immobilization onto the surfaces of ELISA plates of a compound carrier complex and for immunization
ZA928954B (en) * 1991-12-24 1993-05-19 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-A, non-B virus.
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6165730A (en) * 1992-03-06 2000-12-26 N.V. Innogenetics S.A. Hepatitis C virus peptides obtained from the NS4 coding region and their use in diagnostic assays
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
CN1053196C (zh) * 1992-07-16 2000-06-07 株式会社先端生命科学研究所 用于丙型肝炎病毒分类的抗原肽, 含有所述肽的药盒及用所述肽进行分类的方法
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
EP0651807B1 (en) 1993-04-27 2007-09-12 N.V. Innogenetics S.A. New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
IT1270941B (it) * 1993-05-12 1997-05-26 Sorin Biomedica Spa Peptidi di hcv e loro usi.
US7070790B1 (en) * 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
KR19990008122A (ko) * 1995-04-28 1999-01-25 곤도도시유키 항원 펩타이드 화합물 및 면역학적 측정방법
FR2775690B1 (fr) * 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
WO1999058561A1 (fr) * 1998-05-14 1999-11-18 Pasteur Merieux Serums & Vaccins Mimotopes du virus de l'hepatite c
US7052830B1 (en) * 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
ES2248357T3 (es) * 2000-07-07 2006-03-16 Medmira Inc. Composicion de antigeno mosaico de vhc.
AUPQ899400A0 (en) * 2000-07-26 2000-08-17 Csl Limited A method of stabilisation and compositions for use therein
EP1978365B1 (en) 2007-03-16 2010-08-25 Sysmex Corporation Reagent kit and method for measuring HCV antibody
JP4975601B2 (ja) * 2007-03-16 2012-07-11 シスメックス株式会社 Ｈｃｖ抗体測定用試薬キット及びｈｃｖ抗体測定方法
JP4975600B2 (ja) * 2007-03-16 2012-07-11 シスメックス株式会社 Ｈｃｖ抗体測定用試薬キット及びｈｃｖ抗体測定方法
ES2303496B1 (es) * 2008-02-21 2009-07-07 Fundacion Para El Estudio De Las Hepatitis Virales Metodo analitico perfeccionado para la deteccion de hepatitis c oculta, aplicaciones del mismo y su correspondiente kit de diagnostico.
US20100104555A1 (en) * 2008-10-24 2010-04-29 The Scripps Research Institute HCV neutralizing epitopes
FR2987836A1 (fr) * 2012-03-09 2013-09-13 Biomerieux Sa Peptides d'interference et procede de detection de microorganismes
CN114858907B (zh) * 2021-02-04 2025-02-18 北京毅新博创生物科技有限公司 用于诊断新冠病毒感染的质谱模型的构建方法

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JP2702911B2 (ja) * 1985-09-11 1998-01-26 ユナイテツド・バイオメデイカル・インコ−ポレ−テツド 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
US4749259A (en) * 1987-05-15 1988-06-07 Hughes Aircraft Company Liquid crystal image projection with multicolor prepolarizing system
NZ227011A (en) * 1987-11-18 1992-03-26 Chiron Corp Non-a, non-b-hepatitis (hepatitis c) antigens, proteins, nucleotide sequences, vaccines and kits
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
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HU217025B (hu) * 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben
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AU635124B2 (en) * 1990-04-16 1993-03-11 United Biomedical Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and prevention thereof as vaccines
WO1992001714A1 (fr) * 1990-07-24 1992-02-06 Yamanouchi Pharmaceutical Co., Ltd. Antigene du virus de l'hepatite non a, non b
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
JP3114731B2 (ja) * 1990-08-14 2000-12-04 国立感染症研究所長 Ｃ型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法
ATE346302T1 (de) * 1990-08-25 2006-12-15 Bioprocess Pty Ltd Nicht-a, nicht-b hepatitis virus antigen, und diagnostische verfahren.
JP2949822B2 (ja) * 1990-10-03 1999-09-20 住友化学工業株式会社 熱可塑性樹脂組成物
ATE206717T1 (de) * 1990-11-03 2001-10-15 Dade Behring Marburg Gmbh Hcv-spezifische peptide, mittel dazu und ihre verwendung
CA2055149A1 (en) * 1990-11-08 1992-05-09 Hiroaki Okamoto Non-a, non-b hepatitis virus related antigen, antibody, detection systems, polynucleotides and polypeptides
KR920703640A (ko) * 1990-11-29 1992-12-18 테루카츄 아리마 비a비b형 간염 바이러스 항원 단백질
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ZA927243B (en) * 1991-10-07 1994-01-26 Akzo Nv Non-A, Non-B peptides
US6165730A (en) * 1992-03-06 2000-12-26 N.V. Innogenetics S.A. Hepatitis C virus peptides obtained from the NS4 coding region and their use in diagnostic assays

Also Published As

Publication number Publication date
HUT65930A (en) 1994-07-28
BR9106220A (pt) 1993-03-30
DK0644202T3 (da) 1997-09-15
WO1992010514A2 (en) 1992-06-25
HU9202645D0 (en) 1993-01-28
AU9068991A (en) 1992-07-08
NZ240964A (en) 1992-10-28
ATE185350T1 (de) 1999-10-15
JPH05503722A (ja) 1993-06-17
EP0489968B1 (en) 1996-11-06
EP0754704A3 (en) 1997-05-28
JP2995216B2 (ja) 1999-12-27
HU218357B (hu) 2000-08-28
EP0489968A1 (en) 1992-06-17
KR0181343B1 (ko) 1999-04-01
ES2138784T3 (es) 2000-01-16
GR3023664T3 (en) 1997-09-30
DE69030124T2 (de) 1997-09-18
EP0644202B1 (en) 1997-03-05
GR3022089T3 (en) 1997-03-31
EP0644202A1 (en) 1995-03-22
DK0754704T3 (da) 2000-04-03
AU652013B2 (en) 1994-08-11
CY2043A (en) 1998-02-20
HK57597A (en) 1997-05-09
DE69029092D1 (de) 1996-12-12
ES2101388T3 (es) 1997-07-01
CY2053B1 (en) 1998-04-30
KR920703632A (ko) 1992-12-18
WO1992010514A3 (en) 1992-08-20
ATE144993T1 (de) 1996-11-15
EP0754704B1 (en) 1999-10-06
DK0489968T3 (da) 1997-03-24
IL100158A (en) 1998-02-22
ATE149522T1 (de) 1997-03-15
US5922532A (en) 1999-07-13
DE69030124D1 (de) 1997-04-10
EP0754704A2 (en) 1997-01-22
KR0181345B1 (ko) 1999-04-01
KR0181344B1 (ko) 1999-04-01
DE69029092T2 (de) 1997-04-17
SG47062A1 (en) 1998-03-20
GR3032150T3 (en) 2000-04-27

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